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Database: UniProt
Entry: A0A2A2JMI1_9BILA
LinkDB: A0A2A2JMI1_9BILA
Original site: A0A2A2JMI1_9BILA 
ID   A0A2A2JMI1_9BILA        Unreviewed;      3676 AA.
AC   A0A2A2JMI1;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   07-NOV-2018, entry version 4.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:PAV62898.1};
GN   ORFNames=WR25_23787 {ECO:0000313|EMBL:PAV62898.1};
OS   Diploscapter pachys.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Diploscapter.
OX   NCBI_TaxID=2018661 {ECO:0000313|EMBL:PAV62898.1, ECO:0000313|Proteomes:UP000218231};
RN   [1] {ECO:0000313|EMBL:PAV62898.1, ECO:0000313|Proteomes:UP000218231}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PF1309 {ECO:0000313|EMBL:PAV62898.1};
RA   Fradin H., Zegar C., Gutwein M., Lucas J., Kovtun M., Corcoran D.,
RA   Baugh L.R., Kiontke K., Gunsalus K., Fitch D.H., Piano F.;
RT   "Genome architecture and evolution of a unichromosomal asexual
RT   nematode.";
RL   Curr. Biol. 0:0-0(2017).
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:PAV62898.1}.
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DR   EMBL; LIAE01010340; PAV62898.1; -; Genomic_DNA.
DR   Proteomes; UP000218231; Unassembled WGS sequence.
DR   GO; GO:0005623; C:cell; IEA:GOC.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0005219; F:ryanodine-sensitive calcium-release channel activity; IEA:InterPro.
DR   CDD; cd12877; SPRY1_RyR; 1.
DR   CDD; cd12878; SPRY2_RyR; 1.
DR   CDD; cd12879; SPRY3_RyR; 1.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR036300; MIR_dom_sf.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR013333; Ryan_recept.
DR   InterPro; IPR003032; Ryanodine_rcpt.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR035910; RyR/IP3R_RIH_dom_sf.
DR   InterPro; IPR035761; SPRY1_RyR.
DR   InterPro; IPR035764; SPRY2_RyR.
DR   InterPro; IPR035762; SPRY3_RyR.
DR   InterPro; IPR003877; SPRY_dom.
DR   PANTHER; PTHR13715; PTHR13715; 3.
DR   Pfam; PF08709; Ins145_P3_rec; 2.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF01365; RYDR_ITPR; 2.
DR   Pfam; PF02026; RyR; 4.
DR   Pfam; PF00622; SPRY; 3.
DR   PRINTS; PR00795; RYANODINER.
DR   SMART; SM00472; MIR; 3.
DR   SMART; SM00449; SPRY; 3.
DR   SUPFAM; SSF100909; SSF100909; 1.
DR   SUPFAM; SSF49899; SSF49899; 2.
DR   SUPFAM; SSF82109; SSF82109; 1.
DR   PROSITE; PS50188; B302_SPRY; 3.
DR   PROSITE; PS50919; MIR; 4.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000218231};
KW   Reference proteome {ECO:0000313|Proteomes:UP000218231};
KW   Repeat {ECO:0000256|SAAS:SAAS00903904}.
FT   DOMAIN      138    182       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      191    246       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      252    309       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      317    375       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      555    776       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN      989   1187       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     1495   1708       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   COILED     3492   3512       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   3676 AA;  416015 MW;  E013F3633CB8D64E CRC64;
     MADKEETGAG EQDDVSFLRT GDIVCLSCVA SHNRDGVLGS ERVCLCTEGF GNRMCTLENV
     SDKDIPPDIA MCMLYIDNAL SMRALQEMMS ADTDHKAATS GAGGHKTLLY GHAVQLKHVQ
     REACWWTIHP ASKQRSEGEK VRVGDDVILV SVATERYLHM TFNKTYMVIA SFHQTLWNIQ
     SVSSGSIRTR NMGCLFGNDV LRLFHGNDEC LTIPENWSEH PQHNMVIYEG GPAVGQARSL
     WRLELIRVKW HGALVGWEQV FRIKHITSGR YLGVLENAVQ LYHKDKADFD LTAFVMCQNK
     DPKKQMLDEK EEEGMGTATI RYGETNAFIQ HVKTQLWLSY QTSEVTKKGL GKVEEKKAVA
     LKDGHMDDCY TFFMALEEES KSARVIRKCS SVLNRFLKGI DALQNEGSQA PDWIRVDLSE
     VLKLMEDLIE YFAQPTDDQD FEDRQNRLRA LRSRQDLFQE EGVLNMILDT IDKFSQMEAL
     PDFAGLIGED THQTWEDIST YLYLLVASMI KGNHYNCAQF AAAARLDWLF GRLSNPQSAE
     GILDVLYCVL TESPEALNMI NEGHIRSVIS LLEKVGRDPK VLDVLSSLCE GNGMAVRSSQ
     NLITQYLLPG RDLLLQTAMK DHVSSMMPNV LLGVVEGSAL FRRWYFEAEV EHIEQTTKQP
     PYLRVGWANS VGFKPFPGSG DKWGCNGAGD DYYSYGFDGK YMYFGGKGRQ VGLRMLQKGD
     IIGCALDLTI PEIRFSINGS TFPACFKNFN VDGYFFPVMS LSSKVSCRFI FGGDQGRLKY
     GPPQAFSPLV EAINGELQIN ECLSFGDLPK TIYCGPQTIF NNMEPFVPTP IDISSVTLPH
     HALDIQPKFA ENLHELWAQR KIELGWSYGE TRSEIHRKHQ FLNSFDKLPQ AEKQYNMNLA
     IDTMKAIEAL GYHLIVDNPP CRLRPVRLPQ QFQQSNGYKP QPLDTHEIIL PDSLNPLIEA
     LAKNTHNVWA KEKIRKGWTF GMSELVDKDQ KRSPHLVPYE QVATRIKETN RESAAECIRA
     LQLFGLFVEA PAHEHDEIAA KELKARRDNC RTYRAEATYA VTVGKWYFEF EVMTDGFMKI
     GWMDIASSPE QQIGMDDRSY AFDGYLGRKW HQGPEVYGKE WKIGDVIGCF LDLNDRTISF
     SLNGELLLDP SGSEMAFDNV MSGEGLVPAF TLGSGQRGKL NFGQQSNSLK YFTTCGLQEG
     YEPFCVNMYR SMPTWFAKDL AQFETIGANS CFEIGKIPAT GNSPPCLKLT QKASLTEGPS
     EKTKMEFTRL SLPVKCNDSF LRNKDKDALR RTMADYKPRN MSVASSQIRG PRIPKEFDDN
     SDKKSFLRSM MGESKGSHES DEEKSRGSGR SKAQHSFDEA PESTAISQRR RVLTLLSYGL
     SCDDSILTWL KIEDEDHNAW IEELRKSLLE LPHDERLAAE EQLRDMTMEK EKPKKGGLLS
     RLRDSSNTRK KEEKQRQAEK MSHMRKANSR SFDASTMDPP SQSTHHSREH KDVLASGDMP
     LSGPGRQLTI RKSSMKKKKS TKKGESVVVQ EKRSSLVPGG IVDPVAEAAK QESDAAALQA
     YADKVDEYYY GLRIFPGQDP ASVWVGWVTT QFHFYAPSFD GNAGVRKCRF AEVDHHGIIV
     DSIESRSCYM MNAAELLSNV PDASNTKVSG TLIGCIVDTS MGELTFQAAG QDTGLKFRLE
     PGAMLFPACF VIPTATEVVQ FELGRIKYTF PLSAAVFKSC RKSLVPFCPP RLTVEQLQPV
     YWARVPNETL RTTSLKLSDI RGWSVLCDDP VRIMAVYIPE KDQSFDILEM IEKGILLDFH
     RQTLNLYCKL ACHGNQKVAH ILCQHIDEDQ LMYAIKSHYL SGPLRQGFHD LIIAIHLQSH
     AAARLSMRKE YVIPLVPQLA IKNVFDPDTE TRYPQIMGDP LSMLSVMAAE PVKAQFNKDE
     ETKLLPPAFD FDGLKAHVME AMHTATRHAV MSCRDLIGGS NLTHFEPLLK LFDSLLVIGL
     IDDNELEMIL KLIHPIAFDE TYIQGGTKKG LTEIELAECV KIQFVSILDH IGDIQLRHRI
     ESLVSFTEGF VGELQQDQCR RYMEIKQTDM PPAEAAKKTK EFRCPPKEQM FRLLMCKVKE
     DKDPTYLEDD VESDTCPMAD NLQQQLRDFC ELLVEKLGNK DEVAECEEQL ALIEAEEGSW
     VDSLARLVVK VPPPIPQEDN QLQRRGTQSF RDMIVTMLRD WALNNFIESK ELIRSMFNLL
     LRQYSGVREI RDAMAQTYVL HDRNVLDVED FIVYLIQIRE LLTVQFEQAE EAILKRGLWK
     LMNNRIFFQH PDLMRLLSVH ENVMSIMMNI LTAQQGTVEH EGDEVKEKTP VKDASEMVVA
     CSRFLCYFCR TSRQNQKAMF EHLSFLLDNA NMLLVRPSLR GSVPLDVAYS SFMDNNELAL
     ALKEEELDKV AVYLSRCGLQ PNSELITKGY PDIGWDPVEG ERYIDFLRFC VWINGENVEE
     NANLVIRLLI RRPECLGIAL KGEGQGLYAA FKEAIMLSED ISALDSGVEH YMLKSGLLGE
     TPSYPSKETE GDDYIDLGAA TLDFYSSLVD LLAKCAPDPM AIQAGKGDSL RARAILRSLI
     SLEDLFQILS LRFTIPNLTL PSADVLRQRI AKQDKIKQNL VQTFAMVAKL AQSNQSQSMA
     HSHQNRPKSL TSSANKLPRL DESDCYGNNM EEYSSATTSL NENNEGDSES VTLKNQSMMA
     SQEVAPTKEK QPAILHRRSS KFSKTVDDNG PLPGLLPNHK GSVLLFLDRV YGIDTQDMLF
     QILEQSFLPD LRAATMMDSP RALESDTALA LNRYLCNSVL PLLTAHSHFF ADAEHHAALL
     DATLHAVYRM NRLKSLTKNQ RDAVSDFLVA ITRELPPGMM IKLLRKVIVD IKTMTDMNIL
     VPLRLLTLHY ERTGKYYGSG SNHYGVATET EKRLSMLLFY AIFDSLGNRA YDPELFGKAL
     PCMTAIGSAI SPDYSLTTGG EEVAKLNTAA EEGTWIPRPA DVSRCDLNRD FQSVVEQFAE
     HFHDSWASRK LEKGWMYGDS YSRLNLTHPR LKPFSQCRDY ERAFYKERCA ECLKALIAWG
     YHFEMADRDA ADRAHAARQS SGTNIQNFAP KPVDLSSMTL EKEMMTAAEK MAENSHLLWA
     RRVANEINQN GGHMPTQMVP WDLLTDFERR KDRFRAAEIL KFLQYNGYHV TPPTPEDSKS
     DRKNEGERSS VEKRFAYNLL EKLIQYLEQA SVKMRSYKPS QELTRRNSFR KEGQDVKFFE
     KVVLPLMHAY FNAHKNYFLE GSSIVQTGTA SNKEKEMVAN LFCRLAALLR IKNRAFGSVA
     KITVKCLQGL TQALDLRTLV KANSDIVRTS LLTFFNNCAE DLFAAVKELK ENGQYALIRG
     QNLKSWISLE FAHQMIIPVL TTMFNHLARN HFGTDLLLDD IQAACYKMLD SLYMVTGLIA
     TAAQRKSIGY ETDKHRPALG QCLSAFASCF PVAFLEPEFN KNNRYSVLAK TQDQSVQVQE
     MLQNLSTHIP HLDKLLNDVE QASANNVMYS DQPNIYDVDL PLLCSYLAHW YNLGPDGKRS
     SDEKDQRIGT QTTNVASDHI NRIFCSLLRM IKSHVGVDNA PWLCRVTFFA VQIIQNVTCD
     PVKDFTLPIA EKMRRLSEKT YKDEEHMRTH PDDADEGTVA EVIIFFFHFC QELLISGQRP
     FGPRHVRVLP YSHEIH
//
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