ID A0A2A2JNE3_9BILA Unreviewed; 904 AA.
AC A0A2A2JNE3;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=RING-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012483};
DE EC=2.3.2.27 {ECO:0000256|ARBA:ARBA00012483};
GN ORFNames=WR25_17714 {ECO:0000313|EMBL:PAV63235.1};
OS Diploscapter pachys.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Diploscapter.
OX NCBI_TaxID=2018661 {ECO:0000313|EMBL:PAV63235.1, ECO:0000313|Proteomes:UP000218231};
RN [1] {ECO:0000313|EMBL:PAV63235.1, ECO:0000313|Proteomes:UP000218231}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PF1309 {ECO:0000313|EMBL:PAV63235.1};
RA Fradin H., Zegar C., Gutwein M., Lucas J., Kovtun M., Corcoran D.,
RA Baugh L.R., Kiontke K., Gunsalus K., Fitch D.H., Piano F.;
RT "Genome architecture and evolution of a unichromosomal asexual nematode.";
RL Curr. Biol. 0:0-0(2017).
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAV63235.1}.
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DR EMBL; LIAE01010322; PAV63235.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A2JNE3; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000218231; Unassembled WGS sequence.
DR GO; GO:0000151; C:ubiquitin ligase complex; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR043540; RING1/RING2.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR46076:SF3; E3 UBIQUITIN-PROTEIN LIGASE RING1; 1.
DR PANTHER; PTHR46076; E3 UBIQUITIN-PROTEIN LIGASE RING1 / RING 2 FAMILY MEMBER; 1.
DR Pfam; PF13923; zf-C3HC4_2; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000218231};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 54..94
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 136..362
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 374..426
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 481..575
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 610..631
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 707..726
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 136..151
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 157..190
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 226..245
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 261..283
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 284..362
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 374..391
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 392..407
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 412..426
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 503..530
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 531..548
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 549..568
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 617..631
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 904 AA; 100439 MW; 386B5766D14B9BF0 CRC64;
MSTEDPEEKE LPLNTAEGAE ITLTEYDKIR EPHPLLPPST SVRITPKMLS DLTCPICLDL
LSQTMATKEC LHRFCSECIT MALLRGNKEC PTCRKKLVSK RSLRPDPNFD LLINSIFPDR
SVFEKMQSSL WVTAASTESS TGSNSNDDSG ESIESESPDE EITRKRSRDE DSDDSDDDND
MKRLKIDEND EDEEPQQLST GENGDRPTLG TFLHESPSKL EQIGPRSEQN ESKETSSKYP
DCDMDDPDDI VANDGVTAEE LLSLDEYEEI ESDSDESEES NNDDDENSQK SEKGEVKKKR
NVKSIEEGEV VSDESGSEEN GKVEVERKDG KNAEEDDDSS DGWYTDHGTD DEDVDSTERN
SEWLEDIELA TKMELEKRLA KHHKKEGASE ETQKQTAGGS NGNAEKNAGN GEVKIEPNED
NESDTGYDEY VADHDLIEYS FGSIHPEQAL EDIIKAPSLY DAYVPIVYSS SRIIPTEGDF
DEAEELDDGV NGVITTGNEN GNEYGDGDEE NGGNSGDEEP EEPEHDAYEF VDETEEQRVN
EARHNENGHS SGEMSSNPNG QLSAQRDNDN DSENCDLDFY TEEELHEEIE ELNEAVAEIG
EDAVLDLKEE ENDEDSYTTS TFSSSGNTSL ENISDLSSEI ELPLDGKANE TEIAAGESSN
TDTQTSQVAT TSTATTSTNQ FIMNHQMLNR GITSPLFRYP FDTTRLSSGN ATGTPSTSLT
PAASSSSTQN SFISELGIAQ NLSHASLLGQ RLGLAMASSP NETTERISLK DVPTGSCKER
LQKWLADYPS SPLAPEENME ENLERSVEDE DALYAAMSDV DEIEIELLPA ACLTARDIPE
EMLTPRYIRA KHDTTMEHLS EYIHLRVMEE VQSNQFDFDA DPVPTIQRPE HFYVFVSHSM
NLFQ
//
