ID A0A2A2JPY4_9BILA Unreviewed; 274 AA.
AC A0A2A2JPY4;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE RecName: Full=VTT domain-containing protein {ECO:0000259|Pfam:PF09335};
GN ORFNames=WR25_11489 {ECO:0000313|EMBL:PAV63713.1};
OS Diploscapter pachys.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Diploscapter.
OX NCBI_TaxID=2018661 {ECO:0000313|EMBL:PAV63713.1, ECO:0000313|Proteomes:UP000218231};
RN [1] {ECO:0000313|EMBL:PAV63713.1, ECO:0000313|Proteomes:UP000218231}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PF1309 {ECO:0000313|EMBL:PAV63713.1};
RA Fradin H., Zegar C., Gutwein M., Lucas J., Kovtun M., Corcoran D.,
RA Baugh L.R., Kiontke K., Gunsalus K., Fitch D.H., Piano F.;
RT "Genome architecture and evolution of a unichromosomal asexual nematode.";
RL Curr. Biol. 0:0-0(2017).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the TMEM41 family.
CC {ECO:0000256|ARBA:ARBA00025797}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAV63713.1}.
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DR EMBL; LIAE01010297; PAV63713.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A2JPY4; -.
DR STRING; 2018661.A0A2A2JPY4; -.
DR Proteomes; UP000218231; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR045014; TM41A/B.
DR InterPro; IPR032816; VTT_dom.
DR PANTHER; PTHR43220; -; 1.
DR PANTHER; PTHR43220:SF18; TRANSMEMBRANE PROTEIN 41B; 1.
DR Pfam; PF09335; SNARE_assoc; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000218231};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 40..60
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 95..120
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 126..152
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 214..234
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 246..267
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 114..233
FT /note="VTT"
FT /evidence="ECO:0000259|Pfam:PF09335"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 18..32
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 274 AA; 31042 MW; 74AB662FECD2A143 CRC64;
MSSKAARSQN GKNAVVDEIQ PEKSESRQKG ESQEQSNRMY ILPLIFAGFI SCLLLVFLTF
PEVSESDRSQ LKLPRNIEDA KVLGRILSKY KNDNFYSVLL AVISVYITLQ SFAIPGSIFL
TILSGYLFPF PVAILLVCTC SAVGAAVCYL LSHLFGRQFV IRRFPDRIAY WQSQVAAHRD
HLLNYIIFLR VTPILPNWSI NILSPVLDVP LSPFFWGTFL GVAPPSFLYI QAGVTLEQMT
QTNVVWNWQS IFLLTFFAVI SLLPIYFKRK AKSE
//
