ID   A0A2A2JTG1_9BILA        Unreviewed;       859 AA.
AC   A0A2A2JTG1;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   24-JAN-2024, entry version 9.
DE   RecName: Full=SSD domain-containing protein {ECO:0000259|PROSITE:PS50156};
GN   ORFNames=WR25_10558 {ECO:0000313|EMBL:PAV64930.1};
OS   Diploscapter pachys.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Diploscapter.
OX   NCBI_TaxID=2018661 {ECO:0000313|EMBL:PAV64930.1, ECO:0000313|Proteomes:UP000218231};
RN   [1] {ECO:0000313|EMBL:PAV64930.1, ECO:0000313|Proteomes:UP000218231}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PF1309 {ECO:0000313|EMBL:PAV64930.1};
RA   Fradin H., Zegar C., Gutwein M., Lucas J., Kovtun M., Corcoran D.,
RA   Baugh L.R., Kiontke K., Gunsalus K., Fitch D.H., Piano F.;
RT   "Genome architecture and evolution of a unichromosomal asexual nematode.";
RL   Curr. Biol. 0:0-0(2017).
CC   -!- SIMILARITY: Belongs to the patched family.
CC       {ECO:0000256|ARBA:ARBA00005585}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PAV64930.1}.
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DR   EMBL; LIAE01010233; PAV64930.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2A2JTG1; -.
DR   Proteomes; UP000218231; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR003392; Ptc/Disp.
DR   InterPro; IPR000731; SSD.
DR   PANTHER; PTHR10796; PATCHED-RELATED; 1.
DR   PANTHER; PTHR10796:SF90; SSD DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF02460; Patched; 1.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   PROSITE; PS50156; SSD; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000218231};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        236..259
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        265..288
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        300..322
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        342..363
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        370..397
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        436..457
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        669..688
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        694..715
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        722..743
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        777..798
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        805..829
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          235..396
FT                   /note="SSD"
FT                   /evidence="ECO:0000259|PROSITE:PS50156"
SQ   SEQUENCE   859 AA;  97580 MW;  632B71313CE8ECBB CRC64;
     MYWMVLKDRI RDGYTPTNAP SRVETDIIRE FWNSSGDPMI TMMLLKARDK GSMHRPEYLD
     ESQRVIDFLY NNFTVEHKGV TLRFSEMCAP YCNMNKVLQL FKMGYDNELK RVTNGQSPST
     TNNLSYPVAS IGGISINLDR SFFGVRLQNK SLNATKDKGL PIEKRITNME HVELVLTLFR
     GDRENQLRDE QLSKWELAAY EWSIKTYKGN LVELQLVGTE ILDSEMMKDG KRMTPFFAAG
     FGFMITFVSV CVFLSAIYYD ALDRGKILVG IGAVTCPILA IVSTYGLISM LGLRINSFML
     VMPFLVMGIG VDSCFLMIHS WQRMSRNGYS VVERMGMVYE EVCPSITITS LTDFLSFAIG
     ALAPTPETRL FCLATSIAMA FTFILQLVFF GPILALATRF EHNDTKPRQA IGWRDKVDRV
     WQKILRIYCR LIGHRIFTIC IVSATCVYWY FGIIGLMNMK TRLDVAKILP KNSPLQQPNY
     ILTHIVWSEY HPVTVLINNP FDVTNRTQTN RFWELVDEFQ SMPNAKGPES SLIWLKDYIH
     FSYYGEPYDN ALKSVLSDWD FLLGDNEPNK PIDPFKANLT TTKLGQFLRS PFYEHWGPFM
     KVSNSSEGRL KIDRFWMTIA YQNTSSWETR IGLMEQWRSI VARYKDLNAT VWEPNGMFID
     QMLSLRSTAV QTGILTLLCM IVVCSIFIPN PCSVITASIA IASISLGVMG FLSWWHFDLD
     PVVMAAVLMS IGLSVDFIAH VSYHYQLTNK KVIVDGRVVK VPVKGPQEKL EHTMASVGWP
     MIQAGVSTIC CILPLLFLAS YSPSVFVAAI FLVVSWGMLH GLVILPSFLG SLPDCLTDAN
     CYRLFLSTSS EKSCRYAGR
//