ID   A0A2A2JTW5_9BILA        Unreviewed;       729 AA.
AC   A0A2A2JTW5;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   RecName: Full=STAS domain-containing protein {ECO:0000259|PROSITE:PS50801};
GN   ORFNames=WR25_22295 {ECO:0000313|EMBL:PAV65113.1};
OS   Diploscapter pachys.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Diploscapter.
OX   NCBI_TaxID=2018661 {ECO:0000313|EMBL:PAV65113.1, ECO:0000313|Proteomes:UP000218231};
RN   [1] {ECO:0000313|EMBL:PAV65113.1, ECO:0000313|Proteomes:UP000218231}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PF1309 {ECO:0000313|EMBL:PAV65113.1};
RA   Fradin H., Zegar C., Gutwein M., Lucas J., Kovtun M., Corcoran D.,
RA   Baugh L.R., Kiontke K., Gunsalus K., Fitch D.H., Piano F.;
RT   "Genome architecture and evolution of a unichromosomal asexual nematode.";
RL   Curr. Biol. 0:0-0(2017).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC       ECO:0000256|RuleBase:RU362052}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU362052}.
CC   -!- SIMILARITY: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
CC       {ECO:0000256|RuleBase:RU362052}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|RuleBase:RU362052}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PAV65113.1}.
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DR   EMBL; LIAE01010221; PAV65113.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2A2JTW5; -.
DR   STRING; 2018661.A0A2A2JTW5; -.
DR   Proteomes; UP000218231; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008509; F:monoatomic anion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0098661; P:inorganic anion transmembrane transport; IEA:UniProtKB-UniRule.
DR   CDD; cd07042; STAS_SulP_like_sulfate_transporter; 1.
DR   Gene3D; 3.30.750.24; STAS domain; 1.
DR   InterPro; IPR011547; SLC26A/SulP_dom.
DR   InterPro; IPR001902; SLC26A/SulP_fam.
DR   InterPro; IPR002645; STAS_dom.
DR   InterPro; IPR036513; STAS_dom_sf.
DR   NCBIfam; TIGR00815; sulP; 1.
DR   PANTHER; PTHR11814:SF233; ANION TRANSPORTER SULP-4; 1.
DR   PANTHER; PTHR11814; SULFATE TRANSPORTER; 1.
DR   Pfam; PF01740; STAS; 1.
DR   Pfam; PF00916; Sulfate_transp; 1.
DR   SUPFAM; SSF52091; SpoIIaa-like; 1.
DR   PROSITE; PS50801; STAS; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362052};
KW   Reference proteome {ECO:0000313|Proteomes:UP000218231};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU362052};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU362052}; Transport {ECO:0000256|RuleBase:RU362052}.
FT   TRANSMEM        281..303
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362052"
FT   TRANSMEM        315..334
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362052"
FT   TRANSMEM        370..393
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362052"
FT   TRANSMEM        442..458
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362052"
FT   TRANSMEM        470..488
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362052"
FT   TRANSMEM        500..528
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362052"
FT   DOMAIN          556..693
FT                   /note="STAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50801"
FT   REGION          1..39
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        16..39
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   729 AA;  81372 MW;  A4B5BDED667AE545 CRC64;
     MIPSDDKICL GSPSDEECSP SEQLPQHLNS LPSLSSRNPM NQDEFDKRFD YLGPPHEDNL
     EIVKRKLHKR FIRPCSSPNA FFKTLIGFIP ILSWLPKYKW RKDIVPDCIG GFTNGILNVP
     QSIAYASLAN VPSQVGLLTS LFPSISYMMF GTSRHCSIGP FAIVAFIVGQ AIEKFQPGAD
     DALMQYNGTI LDYSYTSTQI ASAMCLQVGV IQLIAVLSGI QFVTAYLSDE IVAGFTTAAS
     LQVMATQFRD LTGAKFEKRV KQDEFMKIFI TLWDVVRSIS TWNICSVILS LSTIAFLVLG
     KYVLDRRLRG LCRSFRIIIP YELIAAIVGI LISYNLDLNR RYGTKIVGDV PTGIPLPSLP
     PKELILNWDL FQQSLTVSII VMAVHLSLAK MFSKQFKYQV DTKQEFYALG AGSLLSSLFP
     VFPNSCSLTR TMLNVNAGSR TQMSTVFSSS ILLVLILYGS RWLGPLPRSI VAATIFVALL
     SAFSKFRQLI DLWRVSKIDF LIWIVAFVAT LVGGVLNGLM AAIGFALFTT VVRSQMPASH
     ILANIPGSMD FRDSQRFKEI CFINDICVIR FDSPLLFMNL ERFQKIIERV VTSWDYKGKT
     GSDECLVKRK SMYGLPNSST RYLIIDCSAF SYVDRMGVNC LKDVHLDMVQ NGVTVWFAGA
     RANLRELFDV CGFYNDVPKS SFYPTIYDAV YFAQQAKNSE GLNHGRCFSL NVGYTNLASS
     SSSSMEHIV
//