ID A0A2A2JU63_9BILA Unreviewed; 260 AA.
AC A0A2A2JU63;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 13.
DE RecName: Full=von Hippel-Lindau disease tumour suppressor beta domain-containing protein {ECO:0000259|Pfam:PF01847};
GN ORFNames=WR25_06639 {ECO:0000313|EMBL:PAV65235.1};
OS Diploscapter pachys.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Diploscapter.
OX NCBI_TaxID=2018661 {ECO:0000313|EMBL:PAV65235.1, ECO:0000313|Proteomes:UP000218231};
RN [1] {ECO:0000313|EMBL:PAV65235.1, ECO:0000313|Proteomes:UP000218231}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PF1309 {ECO:0000313|EMBL:PAV65235.1};
RA Fradin H., Zegar C., Gutwein M., Lucas J., Kovtun M., Corcoran D.,
RA Baugh L.R., Kiontke K., Gunsalus K., Fitch D.H., Piano F.;
RT "Genome architecture and evolution of a unichromosomal asexual nematode.";
RL Curr. Biol. 0:0-0(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAV65235.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LIAE01010215; PAV65235.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A2JU63; -.
DR STRING; 2018661.A0A2A2JU63; -.
DR Proteomes; UP000218231; Unassembled WGS sequence.
DR Gene3D; 2.60.40.780; von Hippel-Lindau disease tumour suppressor, beta domain; 1.
DR InterPro; IPR024053; VHL_beta_dom.
DR InterPro; IPR037140; VHL_beta_dom_sf.
DR InterPro; IPR036208; VHL_sf.
DR Pfam; PF01847; VHL; 1.
DR SUPFAM; SSF49468; VHL; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000218231}.
FT DOMAIN 71..145
FT /note="von Hippel-Lindau disease tumour suppressor beta"
FT /evidence="ECO:0000259|Pfam:PF01847"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 161..182
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 198..260
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 13..28
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 198..212
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 260 AA; 29410 MW; 4996983DDF931C6B CRC64;
MEANDGGGEM QLQDEGEGER DNPHNQQRVA DPLDEFVCTQ GIVRNLTPEL MHIHYNNWKL
YMKTQGLQHI RSTTPGAICH CSFINRSKWV AQVLWINEHG FPTVYGQLMY NQVLYINSYA
GHPWIVRNGI TGEVLLVNGK TAHLNTKILL NIIYRRNIGG QVGRGPPPRI TPADNLPEFA
EPRRPIRPQV LYPIAQAQEQ GQEQNQRQGE RAGVAASGNR RRARPVSPDN EEEEDVDGQI
AGRRSGRRAA GDNQQQQQRR
//
