ID   A0A2A2JUP6_9BILA        Unreviewed;       162 AA.
AC   A0A2A2JUP6;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   22-FEB-2023, entry version 11.
DE   RecName: Full=Ubiquitin-fold modifier-conjugating enzyme 1 {ECO:0000256|ARBA:ARBA00013306, ECO:0000256|PIRNR:PIRNR008716};
GN   ORFNames=WR25_19310 {ECO:0000313|EMBL:PAV65388.1};
OS   Diploscapter pachys.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Diploscapter.
OX   NCBI_TaxID=2018661 {ECO:0000313|EMBL:PAV65388.1, ECO:0000313|Proteomes:UP000218231};
RN   [1] {ECO:0000313|EMBL:PAV65388.1, ECO:0000313|Proteomes:UP000218231}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PF1309 {ECO:0000313|EMBL:PAV65388.1};
RA   Fradin H., Zegar C., Gutwein M., Lucas J., Kovtun M., Corcoran D.,
RA   Baugh L.R., Kiontke K., Gunsalus K., Fitch D.H., Piano F.;
RT   "Genome architecture and evolution of a unichromosomal asexual nematode.";
RL   Curr. Biol. 0:0-0(2017).
CC   -!- FUNCTION: E1-like enzyme which specifically catalyzes the second step
CC       in ufmylation. Ufmylation is involved in reticulophagy (also called ER-
CC       phagy) induced in response to endoplasmic reticulum stress.
CC       {ECO:0000256|PIRNR:PIRNR008716}.
CC   -!- SIMILARITY: Belongs to the ubiquitin-conjugating enzyme family. UFC1
CC       subfamily. {ECO:0000256|ARBA:ARBA00008451,
CC       ECO:0000256|PIRNR:PIRNR008716}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PAV65388.1}.
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DR   EMBL; LIAE01010209; PAV65388.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2A2JUP6; -.
DR   STRING; 2018661.A0A2A2JUP6; -.
DR   Proteomes; UP000218231; Unassembled WGS sequence.
DR   GO; GO:0061657; F:UFM1 conjugating enzyme activity; IEA:InterPro.
DR   GO; GO:0071569; P:protein ufmylation; IEA:InterPro.
DR   Gene3D; 3.10.110.10; Ubiquitin Conjugating Enzyme; 1.
DR   InterPro; IPR016135; UBQ-conjugating_enzyme/RWD.
DR   InterPro; IPR014806; Ufc1.
DR   PANTHER; PTHR12921; UBIQUITIN-FOLD MODIFIER-CONJUGATING ENZYME 1; 1.
DR   PANTHER; PTHR12921:SF0; UBIQUITIN-FOLD MODIFIER-CONJUGATING ENZYME 1; 1.
DR   Pfam; PF08694; UFC1; 1.
DR   PIRSF; PIRSF008716; DUF1782; 1.
DR   SUPFAM; SSF54495; UBC-like; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000218231};
KW   Ubl conjugation pathway {ECO:0000256|PIRNR:PIRNR008716}.
FT   ACT_SITE        115
FT                   /note="Glycyl thioester intermediate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR008716-1"
SQ   SEQUENCE   162 AA;  18558 MW;  C7FB8727A5C960BE CRC64;
     MDEESKSRLK AIPLCKTKAG PRDGDLWIER LKEEYESLIK FAQNNKESGS DWFRLESNEN
     GTKWYGKCWH FHNMVKYEFD VEFDIPVTYP VTAPEIALPE LDGKTAKMYR GGKICLSEHF
     KPLWARNAPK FGIAHAFSLG LGPWLAVEIP DLVEKGLIQP KS
//