ID   A0A2A2JXA8_9BILA        Unreviewed;       762 AA.
AC   A0A2A2JXA8;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   RecName: Full=Protein SDA1 {ECO:0000256|RuleBase:RU365057};
GN   ORFNames=WR25_01236 {ECO:0000313|EMBL:PAV66283.1};
OS   Diploscapter pachys.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Diploscapter.
OX   NCBI_TaxID=2018661 {ECO:0000313|EMBL:PAV66283.1, ECO:0000313|Proteomes:UP000218231};
RN   [1] {ECO:0000313|EMBL:PAV66283.1, ECO:0000313|Proteomes:UP000218231}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PF1309 {ECO:0000313|EMBL:PAV66283.1};
RA   Fradin H., Zegar C., Gutwein M., Lucas J., Kovtun M., Corcoran D.,
RA   Baugh L.R., Kiontke K., Gunsalus K., Fitch D.H., Piano F.;
RT   "Genome architecture and evolution of a unichromosomal asexual nematode.";
RL   Curr. Biol. 0:0-0(2017).
CC   -!- FUNCTION: Required for 60S pre-ribosomal subunits export to the
CC       cytoplasm. {ECO:0000256|RuleBase:RU365057}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC       {ECO:0000256|RuleBase:RU365057}.
CC   -!- SIMILARITY: Belongs to the SDA1 family. {ECO:0000256|ARBA:ARBA00005783,
CC       ECO:0000256|RuleBase:RU365057}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PAV66283.1}.
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DR   EMBL; LIAE01010131; PAV66283.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2A2JXA8; -.
DR   STRING; 2018661.A0A2A2JXA8; -.
DR   Proteomes; UP000218231; Unassembled WGS sequence.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0042273; P:ribosomal large subunit biogenesis; IEA:UniProtKB-UniRule.
DR   GO; GO:0000055; P:ribosomal large subunit export from nucleus; IEA:UniProtKB-UniRule.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR027312; Sda1.
DR   InterPro; IPR048292; SDA1_C.
DR   InterPro; IPR007949; SDA1_MD.
DR   InterPro; IPR012977; SDA1_N.
DR   PANTHER; PTHR12730; HSDA/SDA1-RELATED; 1.
DR   PANTHER; PTHR12730:SF0; PROTEIN SDA1 HOMOLOG; 1.
DR   Pfam; PF21638; SDA1_C; 1.
DR   Pfam; PF05285; SDA1_dom; 1.
DR   Pfam; PF08158; SDA1_HEAT; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
PE   3: Inferred from homology;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU365057};
KW   Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW   ECO:0000256|RuleBase:RU365057};
KW   Reference proteome {ECO:0000313|Proteomes:UP000218231};
KW   Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517,
KW   ECO:0000256|RuleBase:RU365057};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU365057}.
FT   DOMAIN          39..411
FT                   /note="SDA1 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08158"
FT   DOMAIN          544..696
FT                   /note="SDA1 middle"
FT                   /evidence="ECO:0000259|Pfam:PF05285"
FT   DOMAIN          714..757
FT                   /note="SDA1 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF21638"
FT   REGION          468..605
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          695..762
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        468..498
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        499..518
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        519..535
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        536..595
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        730..750
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   762 AA;  89228 MW;  26A2F5DE168BFE54 CRC64;
     MFQEFVEQLS YYEQTMKLLH MQPEQHRMEL EPLLETVTFL SGLAKHYPEE AKTFCDSLFT
     ILRDQAEALD RHVRLSFCKA ILYMRIQGIV DVIRMLELFF ELVKREDKYL RKFILSSISN
     HLKRRYQKKK DPKLFGKIQN FCFQKMKDSR AIVARAAQLV CIDAFRKNLW RDARTTNVIA
     DACFHKLPKI QMTSMKFFLG SKENEEGVSD MSEDDEEGKQ DDAKTVKEVM TSFRHAKKTR
     KRTKNLEKVK KAVDKKKKAK KEGRSKECNL FAIQSLYDPQ QFVDRLFGML EGKKVDRFEI
     RLTRIGLCAR LIGIHRLHTL GFYSYLHRYL QPKQRDVTRI LLYAAQACHE LTPPDTVEQL
     VRVIANSFVT DRNSPEAMTV GINAIREIFA NCPFAATEEL LRDLAEYKTY KNKNVSVAAR
     ALITLFRQMN PKLLHRKDRG RQDQRAIDDE REFVGYAKPA VHNFVAGAEI LDEREEPEQM
     ETDERKKKRN RNRNEEEDSD SELEVSDVDT DEVDTDSDAD EPLAKRKKTE KGSKEEEEDS
     EGEWQDVEHS SDEEMDDEEI EFEDEDEEEE MEDEDEPGDE QLESGADETG QEQEEDVEVD
     PKKKAEDICA NRILTQEDFK QIKQYQLKKQ LIGEKRLKKQ LGKKKRNDDV MLIEEMSEKI
     HNRGTGDGLP RLRDIEQFYK KKKQTKAERM ADIMAGRDED KQFGKPKKNG PHVGKTNRQN
     TKKKVAAMVK AKKRGENRQR SFRDRQKSLR NYLLRQSGIK PK
//