ID A0A2A2K0B4_9BILA Unreviewed; 785 AA.
AC A0A2A2K0B4;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 08-NOV-2023, entry version 16.
DE RecName: Full=Tyrosine-protein phosphatase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=WR25_23194 {ECO:0000313|EMBL:PAV67385.1};
OS Diploscapter pachys.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Diploscapter.
OX NCBI_TaxID=2018661 {ECO:0000313|EMBL:PAV67385.1, ECO:0000313|Proteomes:UP000218231};
RN [1] {ECO:0000313|EMBL:PAV67385.1, ECO:0000313|Proteomes:UP000218231}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PF1309 {ECO:0000313|EMBL:PAV67385.1};
RA Fradin H., Zegar C., Gutwein M., Lucas J., Kovtun M., Corcoran D.,
RA Baugh L.R., Kiontke K., Gunsalus K., Fitch D.H., Piano F.;
RT "Genome architecture and evolution of a unichromosomal asexual nematode.";
RL Curr. Biol. 0:0-0(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAV67385.1}.
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DR EMBL; LIAE01009935; PAV67385.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A2K0B4; -.
DR STRING; 2018661.A0A2A2K0B4; -.
DR Proteomes; UP000218231; Unassembled WGS sequence.
DR GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
DR GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR CDD; cd00047; PTPc; 1.
DR Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 1.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR InterPro; IPR000242; PTP_cat.
DR InterPro; IPR003595; Tyr_Pase_cat.
DR InterPro; IPR000387; Tyr_Pase_dom.
DR PANTHER; PTHR46163:SF7; PROTEIN TYROSINE PHOSPHATASE-LIKE PROTEIN EGG-3; 1.
DR PANTHER; PTHR46163; TYROSINE-PROTEIN PHOSPHATASE-RELATED; 1.
DR Pfam; PF00102; Y_phosphatase; 1.
DR PRINTS; PR00700; PRTYPHPHTASE.
DR SMART; SM00194; PTPc; 1.
DR SMART; SM00404; PTPc_motif; 1.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
DR PROSITE; PS50055; TYR_PHOSPHATASE_PTP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000218231}.
FT DOMAIN 447..699
FT /note="Tyrosine-protein phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS50055"
FT DOMAIN 631..690
FT /note="Tyrosine specific protein phosphatases"
FT /evidence="ECO:0000259|PROSITE:PS50056"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 90..132
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 785 AA; 90488 MW; AC4B5AD02BA08847 CRC64;
MKSSNEVSGT WSKLPNQGLP PGYARDRTSS LASFMNLNGA NEEDFGDMFS LATANDYPMN
DRGRRILLPA GSNNAEDDEA TSRFRKRVKQ MARKETVRPA RSLSPVSRDR DMFEEAGEED
GGQPLQLDQT NRKKKGKGIG YIFTPSAQTQ EQAKVPAQTR RVMIISPGDE EKLKNGPQEK
VYRLDEMKAH WKATRMKLFA ARTAIDVQPE LVERTRFKME AHRKDIRLHG ISPNAISFNS
EQYATEQEIV RSSVGIIEEP VSEEQMRVLV KQCKENIDLT QHLLYSKKYD NKWKPQHRKL
FAEGTEDGKK KNRPLNKQGW VLPLKKLCDK IGISTSFFTH NKHVTLDEAR EYVLKERLAK
TADMIAGSWL TVADRQSVEN PVLMSYLSQT LDARTLALRL AQFKVNIETD MDRVRETGQY
YNNIQLGKRM FAPTRKPKFV QTITGGMERR FEILDNQVNF IPFEHIASDL YKEKCRNTRV
HCRDSTRVVL KYANYDGDDD FIHANRIEGG PLFSKFILTQ APMANTVGDF WRMIYQEKCP
YIFMLISRKH PERCERYWPS TPSDDPLLVF GLTVENRGIC TDRDPLFRIT QLLITGPDGD
KHHVEHWQAD MNNSANLWSP LLLLRLARNC NRPIVVHDHL GISRAACLVA AEVAICNLIK
GPSYKHPVQR AVQFVRSCRP FSVETPMQYI YIHRVVLFFF KDFLGSLRTI ETDYQRWLME
RSGRMFLDDL DAPVPGYRLL SPRVDPDLLR VVGRPERPNY RREAPDVVGE MPMPLQKKLP
FNLID
//
