ID   A0A2A2K8T5_9BILA        Unreviewed;       554 AA.
AC   A0A2A2K8T5;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:PAV70338.1};
GN   ORFNames=WR25_12866 {ECO:0000313|EMBL:PAV70338.1};
OS   Diploscapter pachys.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Diploscapter.
OX   NCBI_TaxID=2018661 {ECO:0000313|EMBL:PAV70338.1, ECO:0000313|Proteomes:UP000218231};
RN   [1] {ECO:0000313|EMBL:PAV70338.1, ECO:0000313|Proteomes:UP000218231}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PF1309 {ECO:0000313|EMBL:PAV70338.1};
RA   Fradin H., Zegar C., Gutwein M., Lucas J., Kovtun M., Corcoran D.,
RA   Baugh L.R., Kiontke K., Gunsalus K., Fitch D.H., Piano F.;
RT   "Genome architecture and evolution of a unichromosomal asexual nematode.";
RL   Curr. Biol. 0:0-0(2017).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PAV70338.1}.
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DR   EMBL; LIAE01009287; PAV70338.1; -; Genomic_DNA.
DR   STRING; 2018661.A0A2A2K8T5; -.
DR   Proteomes; UP000218231; Unassembled WGS sequence.
DR   GO; GO:0097367; F:carbohydrate derivative binding; IEA:InterPro.
DR   GO; GO:0004347; F:glucose-6-phosphate isomerase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0006096; P:glycolytic process; IEA:UniProtKB-KW.
DR   CDD; cd05016; SIS_PGI_2; 1.
DR   InterPro; IPR001672; G6P_Isomerase.
DR   InterPro; IPR046348; SIS_dom_sf.
DR   InterPro; IPR035482; SIS_PGI_2.
DR   InterPro; IPR019239; VapB_antitoxin.
DR   PANTHER; PTHR11469; GLUCOSE-6-PHOSPHATE ISOMERASE; 1.
DR   PANTHER; PTHR11469:SF1; GLUCOSE-6-PHOSPHATE ISOMERASE; 1.
DR   Pfam; PF00342; PGI; 3.
DR   Pfam; PF09957; VapB_antitoxin; 1.
DR   SUPFAM; SSF53697; SIS domain; 1.
DR   PROSITE; PS51463; P_GLUCOSE_ISOMERASE_3; 2.
PE   4: Predicted;
KW   Gluconeogenesis {ECO:0000256|ARBA:ARBA00022432};
KW   Glycolysis {ECO:0000256|ARBA:ARBA00023152};
KW   Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW   Reference proteome {ECO:0000313|Proteomes:UP000218231}.
FT   REGION          61..90
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          117..139
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        66..90
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   554 AA;  61047 MW;  1B506B59EAA8FB65 CRC64;
     MIGVFRIGVA GGGIGRAEHD DVATRRIAAE QAARDWWEAV GQRPARIAVI PFRDEQIVAD
     QQPRQHRFAG NREGREDEAA QDEHGDCQLH EEADRLAGFR AGLYRLGRPR ASSPVVPVSA
     ETGLSPGAGS IRDGHDLPLP MKDGHMSDWS AIEALPSPKL MDLFAKDGDR LKTFSLDVSG
     IHFDWSKTHL TRDAVAAFEA LAKAKDLAGK RDAMFGGQHV NVTEDRPVEH TAERGEGNPD
     SRYDVAIVSN VDGVALEEAI KDFDPSATLL VIASKTFTTK ETMLNAESAM QWFREHGVED
     PYGKVIALTA APDKAMEWGV DETRILPFSE GMDRHFRLTA LHENAPALAA FADLYYTQVR
     HAETRAPFAY DERLRLLPSY LQQLEMESNG KGVTVDGQPV GRPTAAITWG GVGTDXXXXX
     XXIEPGDTLA EDHHRQLLLN AFAQGAALMK GKQVDDPARS YSGDRPSSTI LLDVLDPRTL
     GALIAFYEHR IDDALMAEAI QRSGLKTKRD VVQFVLNRYV NIERQREALE GLRGLGWDGD
     LDAMRTDDPV REWG
//