ID   A0A2A2KFQ1_9BILA        Unreviewed;       727 AA.
AC   A0A2A2KFQ1;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=C2H2-type domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=WR25_15094 {ECO:0000313|EMBL:PAV72698.1};
OS   Diploscapter pachys.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Diploscapter.
OX   NCBI_TaxID=2018661 {ECO:0000313|EMBL:PAV72698.1, ECO:0000313|Proteomes:UP000218231};
RN   [1] {ECO:0000313|EMBL:PAV72698.1, ECO:0000313|Proteomes:UP000218231}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PF1309 {ECO:0000313|EMBL:PAV72698.1};
RA   Fradin H., Zegar C., Gutwein M., Lucas J., Kovtun M., Corcoran D.,
RA   Baugh L.R., Kiontke K., Gunsalus K., Fitch D.H., Piano F.;
RT   "Genome architecture and evolution of a unichromosomal asexual nematode.";
RL   Curr. Biol. 0:0-0(2017).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PAV72698.1}.
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DR   EMBL; LIAE01008722; PAV72698.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2A2KFQ1; -.
DR   STRING; 2018661.A0A2A2KFQ1; -.
DR   Proteomes; UP000218231; Unassembled WGS sequence.
DR   GO; GO:0004386; F:helicase activity; IEA:InterPro.
DR   CDD; cd18808; SF1_C_Upf1; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR045055; DNA2/NAM7-like.
DR   InterPro; IPR041679; DNA2/NAM7-like_C.
DR   InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR047187; SF1_C_Upf1.
DR   PANTHER; PTHR10887; DNA2/NAM7 HELICASE FAMILY; 1.
DR   PANTHER; PTHR10887:SF364; REGULATOR OF NONSENSE TRANSCRIPTS 1; 1.
DR   Pfam; PF13086; AAA_11; 1.
DR   Pfam; PF13087; AAA_12; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000218231}.
FT   DOMAIN          320..412
FT                   /note="DNA2/NAM7 helicase helicase"
FT                   /evidence="ECO:0000259|Pfam:PF13086"
FT   DOMAIN          421..615
FT                   /note="DNA2/NAM7 helicase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13087"
SQ   SEQUENCE   727 AA;  81796 MW;  B2F1AF45C196418D CRC64;
     MITSCPQTSP LLIPMANWSE DVLISQSRFS NSKDLADSVF VAISVERAEQ ERAAKKMRAG
     LIWHDIVRDE RNELVFHFQL PDITNMESKD TMAIRVSIGD FGKIEGPQES KWERHGIITK
     LPDLTDDNYC ILLNGTSQDL TPKWKSNEIT FQVLYNPVPF ERECAALKKF VEVTNFNETI
     RQAILGAEVS LDDLKINDEV PEYDIQGLPP FNSFQQAAIK MAINNRVAII EGPGGTGKTD
     VLAAIAFHLS KNLKEDEILF VCSPSNAAAD ECALRIMKTG LNPVRVVAES RQMLESRVPD
     ILLHRLIRDI LPTEFKKLDN IKKKRKLNNG EQQRFKELKT QAELEIIRQR RIVCCTTSSS
     AMEILREFKP VAIIVDEAGQ GSISNVLVPV MTGANQLILV GDTAQLPPLV TSPKALSAGL
     GVSLMERLGE FGLPKEMLRV QHRMVPSLSA FPNEQFYGGL LLDGENTEKL VSYSSKWKWI
     DVSNPKAFLS SFYEETKVGR SIGNDGQAKE AIVLANKLII SGIDPSDIAI LSFYDGQRRI
     ISRLIRDPIY STRDKKLREI EVSTVDSFQG RENKYIIVCT VRCNERNKLG FISDRRRINL
     ALTRPQAGLF ILGNYELLSV DKTWNALLNC YVNEGVLMEG DLDSMKSIKP KLRTPLSSLP
     PDDENVDEDQ EECTNNFALW FTIYYRSRHP FQCKACNTPA SSYAQAIEHL RSHGHRTKAA
     KVISETK
//