ID A0A2A2KGP1_9BILA Unreviewed; 1515 AA.
AC A0A2A2KGP1;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Myosin motor domain-containing protein {ECO:0000259|PROSITE:PS51456};
GN ORFNames=WR25_14293 {ECO:0000313|EMBL:PAV73196.1};
OS Diploscapter pachys.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Diploscapter.
OX NCBI_TaxID=2018661 {ECO:0000313|EMBL:PAV73196.1, ECO:0000313|Proteomes:UP000218231};
RN [1] {ECO:0000313|EMBL:PAV73196.1, ECO:0000313|Proteomes:UP000218231}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PF1309 {ECO:0000313|EMBL:PAV73196.1};
RA Fradin H., Zegar C., Gutwein M., Lucas J., Kovtun M., Corcoran D.,
RA Baugh L.R., Kiontke K., Gunsalus K., Fitch D.H., Piano F.;
RT "Genome architecture and evolution of a unichromosomal asexual nematode.";
RL Curr. Biol. 0:0-0(2017).
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|PROSITE-ProRule:PRU00782}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00782}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAV73196.1}.
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DR EMBL; LIAE01008638; PAV73196.1; -; Genomic_DNA.
DR Proteomes; UP000218231; Unassembled WGS sequence.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0032982; C:myosin filament; IEA:UniProtKB-KW.
DR GO; GO:0030017; C:sarcomere; IEA:UniProt.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:InterPro.
DR Gene3D; 1.20.5.340; -; 3.
DR Gene3D; 1.20.5.370; -; 1.
DR Gene3D; 1.20.5.4820; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR002928; Myosin_tail.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014751; XRCC4-like_C.
DR PANTHER; PTHR45615; MYOSIN HEAVY CHAIN, NON-MUSCLE; 1.
DR PANTHER; PTHR45615:SF20; MYOSIN-2; 1.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF01576; Myosin_tail_1; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF90257; Myosin rod fragments; 5.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|PROSITE-ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175};
KW Muscle protein {ECO:0000256|ARBA:ARBA00023179};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000218231};
KW Thick filament {ECO:0000256|ARBA:ARBA00022433}.
FT DOMAIN 1..363
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT REGION 237..259
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT REGION 704..731
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 796..818
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1515 AA; 174816 MW; E4B29D9D099F9490 CRC64;
MAKGLYSRLF NWIVKKCNVT LDQKGIDRDH FIGVLDIAGF EIFDFNSFEQ LWINFVNERL
QQFFNHHMFV LEQEEYKREG IDWVFIDFGL DLQACIELIE KPLGIISMLD EECIVPKATD
ATLAQKLVEQ HLGKHPNFVN PPPPKGKQAE AHFAMKHYAG LVRYNVSNWL EKNKDPLNDT
LVQTLKQSQG NELLVEVWQD YTTIEEGLAL AAKGGASKKK GKSGSFMTVS MLYRESLNKL
MTMLNSTHPH FIRCIIPNEK KMSGMIDASL VLNQLTCNGV LEGIRICRKG FPNRTLHPDF
VQRYALLAAD EAIIGKQDPK KGATAMMARL VKEKKLTDEN FKVGLTKVFF KAGIVAHLED
IRDTKLSALI TGLQAQVRWF YQLIERKRRV ERIKAVKTIQ NNIRAWFELQ TWQWFKLYGK
VKPLISSGRI EAQWDKLHET VDRLKNTLIE EEEKKRQFTE GAERLTKETA DLISQLEATK
GSNREIEERM TMMNEQKAAL EGKLADMSSR LEQEEAAAQE ILKEKKRVEQ QAADLKKTCQ
DVDVSLKKVE AEKTAKEHQI RALQDEMRQQ DENIAKLNKE RKNQEEANKK FQEDLQAAEE
QNLAQNKLKT KLMQTLEEAE SSMEQEKRFR ADMDKAKRKA EGELKIAQET MDEIMKAKQD
AENALRKKET ELHNLSLKLE DEQAAVAKLQ KQIQAEEARI KDLGEQLADE KEARQRTERA
RAEQQAEYDE LNEQLEDQVR ATAGQVELSK KKDAELAKCK RDLDEASLKF NEQLASLKKK
GADSIQELLD QIEQLKKQKE RSEKEKNQMQ REFDESSAAL DAETKARTEM ERIAKSHEVR
LLELRLKADE QSRQLHDFIS SKGRLHSENS DLARQVEELT SKIQTANRMR LQLSNEFDQN
RRLAEEESRE RQNLSNLSKT LARELEQLKE SVEDEVAGKN ESSRQLQKAT AELDAWRAKF
EAEGLIGADE FDEVKRRQNQ KTSEIQDQLD ACNAKIVALE NAKSRLTAEA DANKLEAEHY
SAAVSSLEKK QKAFDKVIDE WKKKVDDLYL ELDGSQRDSR SLSAEAHKLR GQHDALADQV
EGLKRENKAL SDEVRDLLES LGETGRATHE MSKNLRRFEM EKDELQRGLD EAEAALEAEE
SKALRCQIEV SQIRAEIEKR IQEKEEEFEN HRKFHQQTID SIQQTLDSET KAKSDLFRVK
KKLEADINEL EIALDHANKA NEDAQKNIKR YLDQIRELQQ TVDEEQKRRE EFREHLLAAE
RKLAVARQEQ EELIVKLEAV ERARRVVEAS VKEHQEQNNE LNAQNVNLAT AKSQLDNEIA
LLKSDIAEAQ QELTASEERG RRATADAAKL AEDLRHDQER SQQLERMKKQ LESQVKDLQE
RSDAAEAAVV KGGAKAIQKG EQRLKTLQTD YEVETRRASE CQKTLQRADR KVREYEFQVS
EDKKNYDKLQ ELVEKLMTKL KQQKKQLDEA EEQANHHLAK YRTVQISLET AEERADSAEQ
CLVRIRSRTR ANEGK
//
