ID   A0A2A2KJ95_9BILA        Unreviewed;       853 AA.
AC   A0A2A2KJ95;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   22-FEB-2023, entry version 15.
DE   RecName: Full=MBD domain-containing protein {ECO:0000259|SMART:SM00391};
GN   ORFNames=WR25_21042 {ECO:0000313|EMBL:PAV74116.1};
OS   Diploscapter pachys.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Diploscapter.
OX   NCBI_TaxID=2018661 {ECO:0000313|EMBL:PAV74116.1, ECO:0000313|Proteomes:UP000218231};
RN   [1] {ECO:0000313|EMBL:PAV74116.1, ECO:0000313|Proteomes:UP000218231}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PF1309 {ECO:0000313|EMBL:PAV74116.1};
RA   Fradin H., Zegar C., Gutwein M., Lucas J., Kovtun M., Corcoran D.,
RA   Baugh L.R., Kiontke K., Gunsalus K., Fitch D.H., Piano F.;
RT   "Genome architecture and evolution of a unichromosomal asexual nematode.";
RL   Curr. Biol. 0:0-0(2017).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PAV74116.1}.
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DR   EMBL; LIAE01008411; PAV74116.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2A2KJ95; -.
DR   Proteomes; UP000218231; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   InterPro; IPR016177; DNA-bd_dom_sf.
DR   InterPro; IPR001739; Methyl_CpG_DNA-bd.
DR   PANTHER; PTHR46024; HISTONE-LYSINE N-METHYLTRANSFERASE EGGLESS; 1.
DR   PANTHER; PTHR46024:SF1; HISTONE-LYSINE N-METHYLTRANSFERASE EGGLESS; 1.
DR   Pfam; PF01429; MBD; 1.
DR   SMART; SM00391; MBD; 1.
DR   SUPFAM; SSF54171; DNA-binding domain; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000218231}.
FT   DOMAIN          728..810
FT                   /note="MBD"
FT                   /evidence="ECO:0000259|SMART:SM00391"
FT   REGION          641..670
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          244..300
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        648..670
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   853 AA;  98108 MW;  86FD8F210D1448E4 CRC64;
     MAKCCLKLFE LFSHMPPDHL SDVEGVISNT SFSTEGRPFC YPDDKLDQIL ARFEKCRTFE
     FEAEFGIDQD QLIVGTAAAV LKELRRNFDF TPFCSTLQLD FDTYRHLGAL LPVVINKCDP
     KTLVSELLCS PADCCVLLVI KYLELNGFNP VVNWKEIKFN LDEWSLDDIK SFNDAIDTGA
     RQVLDGNRKN EEEGKPTISQ EKMESAISET HQMVESTPNK INQISAEITS TIKSMNITDL
     YNFRESLKKD REAEREEYST LMKAQYLLRD EDIEKTRLQL EEAKRAMENA KRLANSVDSA
     YYGITDTFFN QLTLQVGDFV LARPDMNDLF PLLPAKVIEI DGDNSRYRVQ IFETGIINSL
     TAQDVAIPRV TLCERFVEKT ESGSGNDDRM CKYRGAAAFV GLRVAALVKT STSDKEEWMS
     GTVAAMPTAI HNNQFLVFFD ADFDSYVNAP CYFEHPDVFK LFQYKFGEMI LDRFKEKLTI
     QKIVPMVSQS SYDDGSGVDR FNVHALLRFN PFRAKFLKLY FERYPNYQLA RFSKPGPNRP
     PDVTQYYQGG SKHEGFVIYV DRSMCVIRRK EGPYSPGIKC FDYPCRDVSH QHNDESLFRG
     STRIAHINML GDNNLSSRRK HEVYRRMEYI EPTVDIHSLT ENRTQRKSTY LPTDKSRRPT
     SKKQDNAAEL ERKKKCENIY KVQHRLVDPQ PIPSPHVGQC TNACLRGLDS DTYDKRWVYD
     SEGKFLCYSP LYIPLLCGYQ RKIYTFGSVK VNRRTRSVKR SNVVMYHAPC GRPLRSMQDV
     TQFLKATHSE LTIDLFNFDP TVDPGAYVTV DKKYYVGMDF TKDHEHIPIP YVNSVDKGKH
     PAVCCFLKNI SID
//