ID A0A2A2KK59_9BILA Unreviewed; 1332 AA.
AC A0A2A2KK59;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=PHD-type domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=WR25_02425 {ECO:0000313|EMBL:PAV74426.1};
OS Diploscapter pachys.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Diploscapter.
OX NCBI_TaxID=2018661 {ECO:0000313|EMBL:PAV74426.1, ECO:0000313|Proteomes:UP000218231};
RN [1] {ECO:0000313|EMBL:PAV74426.1, ECO:0000313|Proteomes:UP000218231}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PF1309 {ECO:0000313|EMBL:PAV74426.1};
RA Fradin H., Zegar C., Gutwein M., Lucas J., Kovtun M., Corcoran D.,
RA Baugh L.R., Kiontke K., Gunsalus K., Fitch D.H., Piano F.;
RT "Genome architecture and evolution of a unichromosomal asexual nematode.";
RL Curr. Biol. 0:0-0(2017).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00475}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAV74426.1}.
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DR EMBL; LIAE01008330; PAV74426.1; -; Genomic_DNA.
DR EMBL; LIAE01008330; PAV74428.1; -; Genomic_DNA.
DR Proteomes; UP000218231; Unassembled WGS sequence.
DR GO; GO:0000785; C:chromatin; IEA:UniProt.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0008410; F:CoA-transferase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006338; P:chromatin remodeling; IEA:InterPro.
DR Gene3D; 3.40.1080.10; Glutaconate Coenzyme A-transferase; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR047171; BAZ1A.
DR InterPro; IPR004165; CoA_trans_fam_I.
DR InterPro; IPR018501; DDT_dom.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR InterPro; IPR028941; WHIM2_dom.
DR InterPro; IPR013136; WSTF_Acf1_Cbp146.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR46510; BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 1A; 1.
DR PANTHER; PTHR46510:SF1; BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 1A; 1.
DR Pfam; PF01144; CoA_trans; 1.
DR Pfam; PF02791; DDT; 1.
DR Pfam; PF00628; PHD; 1.
DR Pfam; PF10537; WAC_Acf1_DNA_bd; 1.
DR Pfam; PF15613; WSD; 1.
DR SMART; SM00571; DDT; 1.
DR SMART; SM00249; PHD; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 1.
DR PROSITE; PS50827; DDT; 1.
DR PROSITE; PS51136; WAC; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS50016; ZF_PHD_2; 1.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|ARBA:ARBA00023117};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00475}; Reference proteome {ECO:0000313|Proteomes:UP000218231};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 106..217
FT /note="WAC"
FT /evidence="ECO:0000259|PROSITE:PS51136"
FT DOMAIN 483..550
FT /note="DDT"
FT /evidence="ECO:0000259|PROSITE:PS50827"
FT DOMAIN 1094..1142
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT REGION 336..391
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 700..721
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1162..1276
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 337..368
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 369..391
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1162..1189
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1190..1214
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1332 AA; 153127 MW; 889017B158AF9B44 CRC64;
MGGAMDLVSA PGAQVIVVME HVNKNGEPKI LPSCKLPLTG KNVVTRLITD MAVFDVCRKN
GLTLIEVRKD LNIDDIKKAT AAPFKMPLLN KKPFDKAEVP SVKSDEKIFF LEATNEIFFN
YDEFFERTIQ LNSTVWTCEY TGRGGLTYFE AVESEKEAIK SLGDFPVYLE RPILFLVHKY
TKRGRFDDLL NDIYAFMKTR FFLGEECQFQ ETNTYKKVNV KISKIHLIRE WTAPPDANPK
EPIACPGELY RYDVTLLDGQ CMTMRENIPP GCLIRSKASS SKAKLKLFLK NSTFISDERF
EVKKRHLEDG VIESLKWEDI LMGPEPVFPA STQIAKRGRP SLGSSHSLSV VHSNGHSLDS
SINSESSPEK SPKKGKPISE KKQQKINAQR EELASTFEKA RKFGVDISKY ESALKVLSSE
EIAKLKDEIK FARDAYNEKV KEERKQKIKQ RYEYNKKRED LEVDDLKPLP EYSPVPLPSW
VTDDDFGDFL SILQFFNTFA ELLPLKEVRG KSKVYLSDII NAIRCNDPQK SAYADMMKVL
LTVRTDIGDE EDGDEADVTS REEIQLMNIQ QCDPSHPRYG QKIKEITEVH EDIRKIHGMS
VRHLPVDWMT LTEAIRLILL TSGYYTGVST HRHRIFGRGY YKGFEDAGFV FRHKYPETME
RLKTMSVFDL EPKERLELMK VAIDQLLSFA KEAKEARLIR EHESEEAAKE GRKPDPLEVS
KEMSKFKTQM RNYRESARSG KEDFEEKLMG EVAFKELEME EICTARELQR QKVKQIEKEQ
LEVIYELSAV SGLYHLGRDR AYRNYFACYT LPGILVENPI EFDYIGECIE KTPFADWSAY
NSLDEARNAA MACTGDMETC TVHGKRKNER TRWMHIESRE IFEQALKSLN KRGIRELALF
EEMTYYKPWI EDVLEKIEKK IERNDWPTIF MADGQEDPNE LTNIDFHVEM RDLLLDLEDK
LQQGLIGFLD SSIDRQEWRR LLSETGDITS LIKGDIVVKT KEEEEIIYSH DELGRLNPVQ
KLAIAFLQLV QTIQMRFFRP PFVQPSREDS SVNRLTNTFV RWQKSLLQCD SICAIALFLG
TLEPAIMWDK SRLQGKCRLC RKKGAAESLV LCTNCDKCFH LGCVHLDAPA PTDWSCSECN
AEKRKKAAIE KRKATRAVAL AEQMSKMEDE SEGDENSMQT SDKNRKSAGA ERTTTNGHSK
ESTEMVQTSS GRSVKKVVYK EMSGGLSPQL AKPLRTSKRN SLPARTKPKY EEDIDYSESD
SANETPTRMS TRRKRKASEE LIIPSYGRAA IAETYKEKMA QLEKLVHDVR REEFSWPFLE
AVDTKEVSLN FF
//
