ID   A0A2A2KNY6_9BILA        Unreviewed;       518 AA.
AC   A0A2A2KNY6;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   24-JAN-2024, entry version 15.
DE   RecName: Full=DUF726 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=WR25_08779 {ECO:0000313|EMBL:PAV75701.1};
OS   Diploscapter pachys.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Diploscapter.
OX   NCBI_TaxID=2018661 {ECO:0000313|EMBL:PAV75701.1, ECO:0000313|Proteomes:UP000218231};
RN   [1] {ECO:0000313|EMBL:PAV75701.1, ECO:0000313|Proteomes:UP000218231}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PF1309 {ECO:0000313|EMBL:PAV75701.1};
RA   Fradin H., Zegar C., Gutwein M., Lucas J., Kovtun M., Corcoran D.,
RA   Baugh L.R., Kiontke K., Gunsalus K., Fitch D.H., Piano F.;
RT   "Genome architecture and evolution of a unichromosomal asexual nematode.";
RL   Curr. Biol. 0:0-0(2017).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PAV75701.1}.
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DR   EMBL; LIAE01008044; PAV75701.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2A2KNY6; -.
DR   Proteomes; UP000218231; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR007941; DUF726.
DR   PANTHER; PTHR17920:SF3; TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4; 1.
DR   PANTHER; PTHR17920; TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 TMCO4; 1.
DR   Pfam; PF05277; DUF726; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000218231};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        273..299
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        311..337
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          1..95
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   518 AA;  55975 MW;  C50AD3EAEF005C9B CRC64;
     MTMGDSESEA TATKNDPNLT NGEIKDRSRS STPTSGSLEE KLTLSVNGTD KRNLSPSLRR
     AESNRGSTSS FRDTFPQKPQ KSPETMSLNA SSTSSPAVEC KLFTPEKINE ELSSAGRYAF
     ADLVASVLQL DFWNEDDPSM IFYCKTTFQT LIQTMSIPEK AVRGLKAHLE GEEQIGDVAD
     LILAIKKERL VNESGTISLM SSLLFSFVNS GNYDSRDRVL LRHIGTLLAV VWEEFEDVED
     SLASTILNYQ FVESERSKQA REKLQKQKKL KRYLMIGAAS GVGGVLIGLT GGLAAPLVAG
     SIGVLIGSGA LAGLATTAGA AVLGTTFGVA GAGLAGYKMK KRVGAIEEFA VETLTDGSGL
     HCTLVVSGWI DRDTSFEEAF IHQWRHLVHS REQYTLRYES QYLRKLGSAI DYLMGFAVSM
     GIQQTLMGTA LAGLVSAVAW PVALISASSV LDNPWNVCVA RAAEVGEHLA EVLLSRAHGK
     RPISLVGFSL GARVIYHCLL AMSQRAESAG GIFFFIKY
//