ID   A0A2A2KQI0_9BILA        Unreviewed;       819 AA.
AC   A0A2A2KQI0;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   RecName: Full=ubiquitinyl hydrolase 1 {ECO:0000256|ARBA:ARBA00012759};
DE            EC=3.4.19.12 {ECO:0000256|ARBA:ARBA00012759};
GN   ORFNames=WR25_06156 {ECO:0000313|EMBL:PAV76180.1};
OS   Diploscapter pachys.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Diploscapter.
OX   NCBI_TaxID=2018661 {ECO:0000313|EMBL:PAV76180.1, ECO:0000313|Proteomes:UP000218231};
RN   [1] {ECO:0000313|EMBL:PAV76180.1, ECO:0000313|Proteomes:UP000218231}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PF1309 {ECO:0000313|EMBL:PAV76180.1};
RA   Fradin H., Zegar C., Gutwein M., Lucas J., Kovtun M., Corcoran D.,
RA   Baugh L.R., Kiontke K., Gunsalus K., Fitch D.H., Piano F.;
RT   "Genome architecture and evolution of a unichromosomal asexual nematode.";
RL   Curr. Biol. 0:0-0(2017).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PAV76180.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; LIAE01007941; PAV76180.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2A2KQI0; -.
DR   Proteomes; UP000218231; Unassembled WGS sequence.
DR   GO; GO:0004843; F:cysteine-type deubiquitinase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   InterPro; IPR001394; Peptidase_C19_UCH.
DR   InterPro; IPR024729; USP7_ICP0-binding_dom.
DR   InterPro; IPR029346; USP_C.
DR   InterPro; IPR018200; USP_CS.
DR   InterPro; IPR028889; USP_dom.
DR   PANTHER; PTHR24006; UBIQUITIN CARBOXYL-TERMINAL HYDROLASE; 1.
DR   PANTHER; PTHR24006:SF644; UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 7; 1.
DR   Pfam; PF00443; UCH; 1.
DR   Pfam; PF14533; USP7_C2; 1.
DR   Pfam; PF12436; USP7_ICP0_bdg; 1.
DR   SUPFAM; SSF54001; Cysteine proteinases; 1.
DR   PROSITE; PS00973; USP_2; 1.
DR   PROSITE; PS50235; USP_3; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000218231};
KW   Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT   DOMAIN          1..187
FT                   /note="USP"
FT                   /evidence="ECO:0000259|PROSITE:PS50235"
SQ   SEQUENCE   819 AA;  94832 MW;  24561531B7A09B34 CRC64;
     MRLTMVRNFS SPFKNCFLVL ESFREYTEVE TLDGDNKYDA GKEHGLQPAL KGVRFLSFPP
     ILHLHLLRYQ YDSHLNKNSK INNRFPFPDR LDLNEFMDAS DSDSVPANYI YVLHSVLVHI
     GRGSGGHYVA YINNQPMALV QGKTSKWYKF DDSTVSKSDA KTAVEGNFGE ENSESSANAY
     MLAYIREDKI DEICCKISSD EIPQALKERL EFEKAEERKK WNQTEISVLT EKDLVVNFDT
     GINGMNLIDE KENINSLGKQ VKVKKDTELE VLAREIAAKI YGDKSKDTSK YRLWRFSNVS
     YKNPTNNNEI VPRMRPSVLI PRDLHGSNMT MNSMWNREHE LYYLENAAID EPGCSSDYNL
     VFFKFFDVNA RQMRLVGSRF LNVAKKSPAD LAEECIKMTG LPEGTELNFY EEIACNKVNH
     IDRARSLTYS ISNPMDGIII VFEISTERST IVNAKTFCEM LSTTVNIEAC DFDANVMGVG
     FSEDLEHPVQ FRADLVRFSI FLFFKYIFQD CTLFEVAMKI ANLIEYRAGF LLFFHNERHS
     KRPGDRFIKG QELINTKLHD FLDSKVNNVN YRVRETFTIF YTKLSIPLGE FSEFKTQNGY
     LTTIHFARNE KAFFLYRDNE TIDDLLERCR ENYPFSVDGS KRLRFVEMKQ SKYGVIRVIK
     KSLLAKDVFD SCHTTFIRLE ETPLDQIQID SRHEFIISAI RFSIKNDDYF GAPFFIKFNK
     EEVFSMFADR MRLMLNVKKE LFDSLQFSII SPTAYSDKVV RFDIHNQTAR KDLINMIMDL
     GTTSPNKMPF LRVNFPTAGN SKGNSDEFRP AEPAIYIRN
//