ID A0A2A2KQK3_9BILA Unreviewed; 712 AA.
AC A0A2A2KQK3;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=ShKT domain-containing protein {ECO:0000259|PROSITE:PS51670};
GN ORFNames=WR25_21565 {ECO:0000313|EMBL:PAV76097.1};
OS Diploscapter pachys.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Diploscapter.
OX NCBI_TaxID=2018661 {ECO:0000313|EMBL:PAV76097.1, ECO:0000313|Proteomes:UP000218231};
RN [1] {ECO:0000313|EMBL:PAV76097.1, ECO:0000313|Proteomes:UP000218231}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PF1309 {ECO:0000313|EMBL:PAV76097.1};
RA Fradin H., Zegar C., Gutwein M., Lucas J., Kovtun M., Corcoran D.,
RA Baugh L.R., Kiontke K., Gunsalus K., Fitch D.H., Piano F.;
RT "Genome architecture and evolution of a unichromosomal asexual nematode.";
RL Curr. Biol. 0:0-0(2017).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU01005}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAV76097.1}.
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DR EMBL; LIAE01007960; PAV76097.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A2KQK3; -.
DR STRING; 2018661.A0A2A2KQK3; -.
DR Proteomes; UP000218231; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 1.10.1280.10; Di-copper center containing domain from catechol oxidase; 1.
DR InterPro; IPR008922; Di-copper_centre_dom_sf.
DR InterPro; IPR003582; ShKT_dom.
DR InterPro; IPR002227; Tyrosinase_Cu-bd.
DR PANTHER; PTHR11474:SF84; TYROSINASE; 1.
DR PANTHER; PTHR11474; TYROSINASE FAMILY MEMBER; 1.
DR Pfam; PF01549; ShK; 2.
DR Pfam; PF00264; Tyrosinase; 1.
DR PRINTS; PR00092; TYROSINASE.
DR SMART; SM00254; ShKT; 2.
DR SUPFAM; SSF48056; Di-copper centre-containing domain; 1.
DR PROSITE; PS51670; SHKT; 2.
DR PROSITE; PS00497; TYROSINASE_1; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU01005};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000218231};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..712
FT /note="ShKT domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5013330880"
FT DOMAIN 542..576
FT /note="ShKT"
FT /evidence="ECO:0000259|PROSITE:PS51670"
FT DOMAIN 586..621
FT /note="ShKT"
FT /evidence="ECO:0000259|PROSITE:PS51670"
FT REGION 680..712
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 690..712
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 542..576
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01005"
SQ SEQUENCE 712 AA; 81455 MW; 1D8196E315AE68E0 CRC64;
MKILYLLFYV FVVLEATEPH KRVARRQATG NITNPFVQTR REAMIRRRLA REPPRDCSDA
PDENIKTTCL MIRAMDTQTR RRLARQAMRN IIPQAPAGPP NWLQPLPVPG NARGQTAYHP
YDCMTITCLC PFFAGRIVGG NCILANGQPL LMSYRKEYRM MTEDERNRWH RALNVLKRNG
EYDRMSYQHF EVGVGSGAHS GPGFLPWHRE FLKRFEIALR MVDPSVAIPY WDSVMDSYLP
DPRDSIFFSD LFVGMPDWYG NVVSGPFAYW RTLDGRAAIL RALGREGQLF TEAQVNNIVA
QNTIENTMAF TAPQLGCPYP NNYGAIEYTH SNIHLFIGGD MKPPSTSSND VRRIYEAKVI
FWMHHSFVDY LWELWRQLKQ PRWYREVAYS ADHGYCTNWL HFSYGPMRPF PYLMNRDGLS
NSYTDQMYRY APRATCSFQN PSCGSPYLFC DTRGYPHCVA KIKINGNCMG FEAYDSCYAG
RCWYGRCVPG AWARAAKTAE LNNETMIPME LFEAALEEPK KAEIPLIKSI KVEFSTPLFN
DCFNRHPCCT AWAESGSCNS EPEYMGVYCA ASCHVCQPDY NITNPCLDRH VNCRPWKEAG
MCSGASADFM SENCRESCEK CELDREDQCT IDGKPVPVPS TEKLKESIRD YSIEKKVKDA
VAKAKLVRIS KKKQEIRNEM AEAKKIPMHK NSGTTGTENG RHIVQNNLPG RS
//
