ID A0A2A2KQK5_9BILA Unreviewed; 782 AA.
AC A0A2A2KQK5;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=ubiquitinyl hydrolase 1 {ECO:0000256|ARBA:ARBA00012759};
DE EC=3.4.19.12 {ECO:0000256|ARBA:ARBA00012759};
GN ORFNames=WR25_06156 {ECO:0000313|EMBL:PAV76178.1};
OS Diploscapter pachys.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Diploscapter.
OX NCBI_TaxID=2018661 {ECO:0000313|EMBL:PAV76178.1, ECO:0000313|Proteomes:UP000218231};
RN [1] {ECO:0000313|EMBL:PAV76178.1, ECO:0000313|Proteomes:UP000218231}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PF1309 {ECO:0000313|EMBL:PAV76178.1};
RA Fradin H., Zegar C., Gutwein M., Lucas J., Kovtun M., Corcoran D.,
RA Baugh L.R., Kiontke K., Gunsalus K., Fitch D.H., Piano F.;
RT "Genome architecture and evolution of a unichromosomal asexual nematode.";
RL Curr. Biol. 0:0-0(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAV76178.1}.
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DR EMBL; LIAE01007941; PAV76178.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A2KQK5; -.
DR Proteomes; UP000218231; Unassembled WGS sequence.
DR GO; GO:0004843; F:cysteine-type deubiquitinase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR001394; Peptidase_C19_UCH.
DR InterPro; IPR024729; USP7_ICP0-binding_dom.
DR InterPro; IPR029346; USP_C.
DR InterPro; IPR018200; USP_CS.
DR InterPro; IPR028889; USP_dom.
DR PANTHER; PTHR24006; UBIQUITIN CARBOXYL-TERMINAL HYDROLASE; 1.
DR PANTHER; PTHR24006:SF644; UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 7; 1.
DR Pfam; PF00443; UCH; 1.
DR Pfam; PF14533; USP7_C2; 1.
DR Pfam; PF12436; USP7_ICP0_bdg; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR PROSITE; PS00973; USP_2; 1.
DR PROSITE; PS50235; USP_3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000218231};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT DOMAIN 1..210
FT /note="USP"
FT /evidence="ECO:0000259|PROSITE:PS50235"
SQ SEQUENCE 782 AA; 90469 MW; AB238438D95315C5 CRC64;
MKSFVKCTGV KFESSKIETF YDLQLNVQSK AVGSMKKKRF DLLESFREYT EVETLDGDNK
YDAGKEHGLQ PALKGVRFLS FPPILHLHLL RYQYDSHLNK NSKINNRFPF PDRLDLNEFM
DASDSDSVPA NYIYVLHSVL VHIGRGSGGH YVAYINNQPM ALVQGKTSKW YKFDDSTVSK
SDAKTAVEGN FGEENSESSA NAYMLAYIRE DKIDEICCKI SSDEIPQALK ERLEFEKAEE
RKKWNQTEIS VLTEKDLVVN FDTGINGMNL IDEKENINSL GKQVKVKKDT ELEVLAREIA
AKIYGDKSKD TSKYRLWRFS NVSYKNPTNN NEIVPRMRPS VLIPRDLHGS NMTMNSMWNR
EHELYYLENA AIDEPGCSSD YNLVFFKFFD VNARQMRLVG SRFLNVAKKS PADLAEECIK
MTGLPEGTEL NFYEEIACNK VNHIDRARSL TYSISNPMDG IIIVFEISTE RSTIVNAKTF
CEMLSTTVNI EACDFDANVM GVGFSEDLEH PVQFRADLDC TLFEVAMKIA NLIEYRAGFL
LFFHNERHSK RPGDRFIKGQ ELINTKLHDF LDSKVNNVNY RVRETFTIFY TKLSIPLGEF
SEFKTQNGYL TTIHFARNEK AFFLYRDNET IDDLLERCRE NYPFSVDGSK RLRFVEMKQS
KYGVIRVIKK SLLAKDVFDS CHTTFIRLEE TPLDQIQIDS RHEFIISAIR FSIKNDDYFG
APFFIKVGFE FIHNFFMLYS SLNFIFQRRN HILSQNFVKS SNNINFSSIK KRCFRCSLIE
CA
//
