ID A0A2A2KYJ3_9BILA Unreviewed; 786 AA.
AC A0A2A2KYJ3;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=SH3 domain-containing protein {ECO:0000259|PROSITE:PS50002};
GN ORFNames=WR25_21931 {ECO:0000313|EMBL:PAV78937.1};
OS Diploscapter pachys.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Diploscapter.
OX NCBI_TaxID=2018661 {ECO:0000313|EMBL:PAV78937.1, ECO:0000313|Proteomes:UP000218231};
RN [1] {ECO:0000313|EMBL:PAV78937.1, ECO:0000313|Proteomes:UP000218231}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PF1309 {ECO:0000313|EMBL:PAV78937.1};
RA Fradin H., Zegar C., Gutwein M., Lucas J., Kovtun M., Corcoran D.,
RA Baugh L.R., Kiontke K., Gunsalus K., Fitch D.H., Piano F.;
RT "Genome architecture and evolution of a unichromosomal asexual nematode.";
RL Curr. Biol. 0:0-0(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAV78937.1}.
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DR EMBL; LIAE01007493; PAV78937.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A2KYJ3; -.
DR STRING; 2018661.A0A2A2KYJ3; -.
DR Proteomes; UP000218231; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR Gene3D; 1.20.1270.350; Dedicator of cytokinesis N-terminal subdomain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR027007; C2_DOCK-type_domain.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR026791; DOCK.
DR InterPro; IPR032376; DOCK_N.
DR InterPro; IPR042455; DOCK_N_sub1.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR45653; DEDICATOR OF CYTOKINESIS; 1.
DR PANTHER; PTHR45653:SF10; MYOBLAST CITY, ISOFORM B; 1.
DR Pfam; PF14429; DOCK-C2; 1.
DR Pfam; PF16172; DOCK_N; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000218231};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 4..76
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
SQ SEQUENCE 786 AA; 89581 MW; 6A4008F23E18DA96 CRC64;
MKETKQRRAI AQCNFEPSTS HQNQLIERQF PLSFLNFSIG DRLQIISTND DWAFGSCEAS
AKEGLFPLNA VQLIDESGAD TEKTEDDSSS REAKLLVKEI DYAIHRWWKR LKSIYSKQAE
VYYMQDILDY MDDLLSVRKK IIVGGIPSDE LNSLRLTVAF RIDKGNMQMG LEVTIRRSNG
QPYLPDSISL LQCYEEHVLS QKKVIAEIKD KSTDRVPEVF SLLVTIKSIQ LLTKFNCHIG
MALYDLDAKQ FFTDDFVFQW KGSEPTNKEV NFKALFSCFS KSDQSRRIAL VTRVYQIAPV
ESSTTSLKRS LETTPSSHYC KQEYAFDLLE VSAVFSRPEI SNDGRERVIF LNRDQDFATV
LKTFLQSGKM PKYSGTSEDV RFLISTQLVE GSAHDIRLKK PHFYNSKNPP VTLARFDQLQ
FVGELRNELH LVLSGCELTG KERNIEARLC VVESNGYPLK DGPIALAYAH ILRDASLIAD
GEHELLVYKT ESTHFDDENI SYMELLKEIA TNGMKPHANG FTLSEKSSIN IATRACSTIL
TQNNHLRNIL QWRKNASTLQ SSLQALSVPV GETKVDMMRF MHPLLDSLFE VWEDKDSLLL
PAFDVIVAVL RITDEQAFAE YLPILDTYIQ RFPYETAAFK LLQCLNHYIE SAVQNNNEKT
RNSLKEMGSI FRLIMQSMKC SRTFNTDPTF TALFSAQLGS VLRSLVSLMS ESRERMNVQN
TALRHMPTII DPIYKSHSLD VDRLCNFILD VLGNFGENIV ARERLSFISQ LIGTELFAVG
FLFISK
//
