ID   A0A2A2KZ21_9BILA        Unreviewed;       257 AA.
AC   A0A2A2KZ21;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   08-NOV-2023, entry version 11.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:PAV79073.1};
GN   ORFNames=WR25_14497 {ECO:0000313|EMBL:PAV79073.1};
OS   Diploscapter pachys.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Diploscapter.
OX   NCBI_TaxID=2018661 {ECO:0000313|EMBL:PAV79073.1, ECO:0000313|Proteomes:UP000218231};
RN   [1] {ECO:0000313|EMBL:PAV79073.1, ECO:0000313|Proteomes:UP000218231}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PF1309 {ECO:0000313|EMBL:PAV79073.1};
RA   Fradin H., Zegar C., Gutwein M., Lucas J., Kovtun M., Corcoran D.,
RA   Baugh L.R., Kiontke K., Gunsalus K., Fitch D.H., Piano F.;
RT   "Genome architecture and evolution of a unichromosomal asexual nematode.";
RL   Curr. Biol. 0:0-0(2017).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PAV79073.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; LIAE01007470; PAV79073.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2A2KZ21; -.
DR   STRING; 2018661.A0A2A2KZ21; -.
DR   Proteomes; UP000218231; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0042500; F:aspartic endopeptidase activity, intramembrane cleaving; IEA:InterPro.
DR   GO; GO:0016485; P:protein processing; IEA:InterPro.
DR   InterPro; IPR001108; Peptidase_A22A.
DR   PANTHER; PTHR10202; PRESENILIN; 1.
DR   PANTHER; PTHR10202:SF25; PRESENILIN SPE-4; 1.
DR   Pfam; PF01080; Presenilin; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000218231};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        15..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        67..90
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        96..118
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        130..151
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   257 AA;  28727 MW;  0DE44AC0B2DC9FE0 CRC64;
     MLPEIAGILC LFKDLRSVIL PVLFNICLTL FSWIKVYEMK TDMRIVPAYY FDTSSSLTTG
     SMLLDGLLNG LTSTVLIAVV SFGMLALALY DFRRLVQFWL SFTCITILYA MSGSFFYDAL
     HAFAPLSTEV CIATASALCF FYGTVGVYAF FFSAPNGLHQ FYVCCNCSFI SLFYLRSFPG
     ETACFECILT CKISDAFAVL NFYGPLRKVQ EKAGDYSANV LRFLMFSDNR GEDRMDAAGD
     EREVEIMQDG SEVEDGS
//