ID   A0A2A2L0C0_9BILA        Unreviewed;       589 AA.
AC   A0A2A2L0C0;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   RecName: Full=Cytosol aminopeptidase domain-containing protein {ECO:0000259|PROSITE:PS00631};
GN   ORFNames=WR25_19090 {ECO:0000313|EMBL:PAV79716.1};
OS   Diploscapter pachys.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Diploscapter.
OX   NCBI_TaxID=2018661 {ECO:0000313|EMBL:PAV79716.1, ECO:0000313|Proteomes:UP000218231};
RN   [1] {ECO:0000313|EMBL:PAV79716.1, ECO:0000313|Proteomes:UP000218231}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PF1309 {ECO:0000313|EMBL:PAV79716.1};
RA   Fradin H., Zegar C., Gutwein M., Lucas J., Kovtun M., Corcoran D.,
RA   Baugh L.R., Kiontke K., Gunsalus K., Fitch D.H., Piano F.;
RT   "Genome architecture and evolution of a unichromosomal asexual nematode.";
RL   Curr. Biol. 0:0-0(2017).
CC   -!- SIMILARITY: Belongs to the peptidase M17 family.
CC       {ECO:0000256|ARBA:ARBA00009528}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PAV79716.1}.
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DR   EMBL; LIAE01007377; PAV79713.1; -; Genomic_DNA.
DR   EMBL; LIAE01007377; PAV79714.1; -; Genomic_DNA.
DR   EMBL; LIAE01007377; PAV79715.1; -; Genomic_DNA.
DR   EMBL; LIAE01007377; PAV79716.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2A2L0C0; -.
DR   STRING; 2018661.A0A2A2L0C0; -.
DR   Proteomes; UP000218231; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0030145; F:manganese ion binding; IEA:InterPro.
DR   GO; GO:0070006; F:metalloaminopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.630.10; Zn peptidases; 1.
DR   InterPro; IPR011356; Leucine_aapep/pepB.
DR   InterPro; IPR000819; Peptidase_M17_C.
DR   PANTHER; PTHR11963; LEUCINE AMINOPEPTIDASE-RELATED; 1.
DR   PANTHER; PTHR11963:SF23; ZGC:152830; 1.
DR   Pfam; PF00883; Peptidase_M17; 1.
DR   PRINTS; PR00481; LAMNOPPTDASE.
DR   SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
DR   PROSITE; PS00631; CYTOSOL_AP; 1.
PE   3: Inferred from homology;
KW   Aminopeptidase {ECO:0000256|ARBA:ARBA00022438};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Protease {ECO:0000256|ARBA:ARBA00022670};
KW   Reference proteome {ECO:0000313|Proteomes:UP000218231}.
FT   DOMAIN          349..356
FT                   /note="Cytosol aminopeptidase"
FT                   /evidence="ECO:0000259|PROSITE:PS00631"
SQ   SEQUENCE   589 AA;  65196 MW;  78B1DCCF62ACF490 CRC64;
     MSFRQFLSTN LVKATSVSDA AFDGVILVAS GREMLSEFKP INNLTSVVQN FLEIHKSALN
     LASLVQVDPA IIPSGRLILS GTGPVTRDYD DVRRFQKAGK EGAKLALQVG LRSPLLVTLP
     HPRFPNAELV SALGALTPIY TPLNVREATN RTKFEQMGIL QLNENSKYSL VDLVAALDAS
     FTVSRDIGDQ GPERMTPPRV AEYVKHAFDN SIIKVQVEDN QQVIEKEYPL MAAVNRAANT
     IERHQARLIR LEYSGEGEAQ ETLFLVGKGV TLDTGGCDLK ISGHMHGMCR DKYGSAVVAG
     FFKALEILKP TGVKVIGYMC MVRNSIGENA YTTDEVLMSR SGKRVHIYNT DAEGRLTMLD
     PLTQAKEEAL NAKNPHLFTL ATLTGHEVLS YGYYAAIMDN GPAKKSGWSR RIQEIGDEFG
     QPIEISRLHP EDFAFMEAEC EQADLRQGNT KPSTQTLRGH QAPGAFLMMG SRIDEHGNDS
     SHPLKFSHMD LGSCQGDHPD TSFPNPLLTL VAGMCNRPQI LEIQLARKLS ELNQASNQLA
     MDKAKLQENL RNVCFIFIFI LKLIFRLESQ SKKNLAELLK WSGKKKDSY
//