ID A0A2A2L451_9BILA Unreviewed; 778 AA.
AC A0A2A2L451;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE RecName: Full=Cullin family profile domain-containing protein {ECO:0000259|PROSITE:PS50069};
DE Flags: Fragment;
GN ORFNames=WR25_04768 {ECO:0000313|EMBL:PAV80920.1};
OS Diploscapter pachys.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Diploscapter.
OX NCBI_TaxID=2018661 {ECO:0000313|EMBL:PAV80920.1, ECO:0000313|Proteomes:UP000218231};
RN [1] {ECO:0000313|EMBL:PAV80920.1, ECO:0000313|Proteomes:UP000218231}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PF1309 {ECO:0000313|EMBL:PAV80920.1};
RA Fradin H., Zegar C., Gutwein M., Lucas J., Kovtun M., Corcoran D.,
RA Baugh L.R., Kiontke K., Gunsalus K., Fitch D.H., Piano F.;
RT "Genome architecture and evolution of a unichromosomal asexual nematode.";
RL Curr. Biol. 0:0-0(2017).
CC -!- SIMILARITY: Belongs to the cullin family.
CC {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC ECO:0000256|RuleBase:RU003829}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAV80920.1}.
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DR EMBL; LIAE01007221; PAV80920.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A2L451; -.
DR STRING; 2018661.A0A2A2L451; -.
DR Proteomes; UP000218231; Unassembled WGS sequence.
DR GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR Gene3D; 1.20.1310.10; Cullin Repeats; 4.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR045093; Cullin.
DR InterPro; IPR016158; Cullin_homology.
DR InterPro; IPR036317; Cullin_homology_sf.
DR InterPro; IPR001373; Cullin_N.
DR InterPro; IPR019559; Cullin_neddylation_domain.
DR InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11932; CULLIN; 1.
DR PANTHER; PTHR11932:SF169; CULLIN-1; 1.
DR Pfam; PF00888; Cullin; 1.
DR Pfam; PF10557; Cullin_Nedd8; 1.
DR SMART; SM00182; CULLIN; 1.
DR SMART; SM00884; Cullin_Nedd8; 1.
DR SUPFAM; SSF75632; Cullin homology domain; 1.
DR SUPFAM; SSF74788; Cullin repeat-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50069; CULLIN_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000218231}.
FT DOMAIN 423..649
FT /note="Cullin family profile"
FT /evidence="ECO:0000259|PROSITE:PS50069"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:PAV80920.1"
SQ SEQUENCE 778 AA; 90706 MW; ABEE0C0813FCED3D CRC64;
GSKMAAVNGI DPRVAENGPV PGESRLDQDW LTLTQGLDIV YGMRENMNFE RFMQFYTTVH
NYCSGVGSEH SNGADLIGGD LYERLEAYIS RHVVDKMNTI KHLRGEELLH FYYAEWDSFQ
FSSRTMSGMF DYLNRHWIQN KKNKDKSNVH NINTLTLLKW RELLFMGLQE YLTPALLELI
QRDRDGIKIS TSIIRGIIQS YVVLGISEHE PKTKGANTSG KESILNDGLV IYREHFESSF
LKRTEEYYAA EASNFLQNGS VVEYTKKVEK RFEEEQNRCE TYMNGVTQTP LAKTLEKVLI
QSKIEFFQGE FGELLAQHKD DDIARMYKLC ERVDNGLEEL RIALERHTIR EGNSELDKVS
EEAFSNPKTY INTILDVYKR YAKLISDAFK MDNSFFQALD KASFTFINSN SVTRKAGKFA
AYKSPELLAR YCDGFLRKSR EQPREEELER IIEDVMTIFK YIEDKDMFSR HYSKLLSKRL
IYNISASEDA ENGMISKLRE LCGMEYTRKL NEMIKEAKLS QGINEVFSPM CKRAEGVDFE
VMLLTSCMWP TMMPLRVHLP EKLNKCHEEF KKFYNLTYSG RKLEWILSQS RGEVAAYCFK
SKTYKFQMTA TQIAVIDMFN RNTSFEFSFL FSSLGMDKPT LFQAVDSLVK SLLLKHSKDA
IEEMYADDTV ISLNEGYTNK NIRLDLTKRI KGISNRETEV ERKHDDRDRN NIIKACIVRI
MKTRRQITHT DLMTEVLQQL ASRFKPEVQM IRICIGDLIQ DEYMKRDQEQ MNKYEYIA
//
