ID A0A2A2L4C1_9BILA Unreviewed; 372 AA.
AC A0A2A2L4C1;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=Nuclear receptor domain-containing protein {ECO:0000259|PROSITE:PS51030};
GN ORFNames=WR25_25972 {ECO:0000313|EMBL:PAV80993.1};
OS Diploscapter pachys.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Diploscapter.
OX NCBI_TaxID=2018661 {ECO:0000313|EMBL:PAV80993.1, ECO:0000313|Proteomes:UP000218231};
RN [1] {ECO:0000313|EMBL:PAV80993.1, ECO:0000313|Proteomes:UP000218231}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PF1309 {ECO:0000313|EMBL:PAV80993.1};
RA Fradin H., Zegar C., Gutwein M., Lucas J., Kovtun M., Corcoran D.,
RA Baugh L.R., Kiontke K., Gunsalus K., Fitch D.H., Piano F.;
RT "Genome architecture and evolution of a unichromosomal asexual nematode.";
RL Curr. Biol. 0:0-0(2017).
CC -!- SIMILARITY: Belongs to the nuclear hormone receptor family.
CC {ECO:0000256|ARBA:ARBA00005993}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAV80993.1}.
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DR EMBL; LIAE01007220; PAV80993.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A2L4C1; -.
DR STRING; 2018661.A0A2A2L4C1; -.
DR Proteomes; UP000218231; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 3.30.50.10; Erythroid Transcription Factor GATA-1, subunit A; 1.
DR InterPro; IPR035500; NHR-like_dom_sf.
DR InterPro; IPR001628; Znf_hrmn_rcpt.
DR InterPro; IPR013088; Znf_NHR/GATA.
DR PANTHER; PTHR46397:SF5; NR LBD DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR46397; NUCLEAR HORMONE RECEPTOR FAMILY-RELATED; 1.
DR Pfam; PF00105; zf-C4; 1.
DR SMART; SM00399; ZnF_C4; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR SUPFAM; SSF48508; Nuclear receptor ligand-binding domain; 1.
DR PROSITE; PS00031; NUCLEAR_REC_DBD_1; 1.
DR PROSITE; PS51030; NUCLEAR_REC_DBD_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000218231};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 3..89
FT /note="Nuclear receptor"
FT /evidence="ECO:0000259|PROSITE:PS51030"
SQ SEQUENCE 372 AA; 42468 MW; 47163ABF977071ED CRC64;
MRRDICKICE SPSANSLHFG CMSCKACAAF FRRTVALDIS YNCIHGDQKC QIHYVVQSRR
GRDKKEQKEK EAKLKENETI GVVMAANSFA DSHGYESPRE GSSRADCEDS IETVLQLHLK
LESDLNKRRR IAFTNTTMRD FFGGLCKLVE FTLSSLSHSI DKLPANANAF LRRSGNITIT
FELQPYARAD LRNFDYRTYQ GYAKFEYIMF FDYIQGFYGF DRLSSPSKNM LFRCGAAVDH
IFTSAYLSTK LGFDEMILVM QDGQAITLRN ALTGMEPHAA SFFSSNEEFE KYNLFKTKRR
RQSDFGQNED DFVSLSIQAS LAGFNLVSSN YFRSEVVELI NSLLIITIFE IGGCDQVIKE
LLDDKTIFEQ PQ
//
