ID   A0A2A2L996_9BILA        Unreviewed;       962 AA.
AC   A0A2A2L996;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   13-SEP-2023, entry version 22.
DE   RecName: Full=Non-specific serine/threonine protein kinase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=WR25_24719 {ECO:0000313|EMBL:PAV82769.1};
OS   Diploscapter pachys.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Diploscapter.
OX   NCBI_TaxID=2018661 {ECO:0000313|EMBL:PAV82769.1, ECO:0000313|Proteomes:UP000218231};
RN   [1] {ECO:0000313|EMBL:PAV82769.1, ECO:0000313|Proteomes:UP000218231}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PF1309 {ECO:0000313|EMBL:PAV82769.1};
RA   Fradin H., Zegar C., Gutwein M., Lucas J., Kovtun M., Corcoran D.,
RA   Baugh L.R., Kiontke K., Gunsalus K., Fitch D.H., Piano F.;
RT   "Genome architecture and evolution of a unichromosomal asexual nematode.";
RL   Curr. Biol. 0:0-0(2017).
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family.
CC       {ECO:0000256|ARBA:ARBA00007381}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PAV82769.1}.
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DR   EMBL; LIAE01007028; PAV82769.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2A2L996; -.
DR   Proteomes; UP000218231; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   CDD; cd10170; HSP70_NBD; 1.
DR   Gene3D; 3.30.30.30; -; 1.
DR   Gene3D; 3.30.420.40; -; 2.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR19375; HEAT SHOCK PROTEIN 70KDA; 1.
DR   PANTHER; PTHR19375:SF184; STRESS-70 PROTEIN, MITOCHONDRIAL; 1.
DR   Pfam; PF00012; HSP70; 1.
DR   PRINTS; PR00301; HEATSHOCK70.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR   PROSITE; PS01036; HSP70_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000218231}.
FT   REGION          454..522
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          545..568
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          581..619
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          641..673
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          692..717
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          865..897
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        465..483
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        493..522
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        548..562
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        692..709
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        866..897
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   962 AA;  109633 MW;  7022935028E3EEAD CRC64;
     MFDSDIKRIS STSNNNQNIR DAIAIDIGTS KCRISICKDQ HVQIVEHESN RAVPTYVARS
     EQGDWLVGKL AENYSVSLPS VAYDIRWLTE KTYADVNYDK EYLFNFAKHK SPTDLVIIEL
     PLPKEAGNVA KEIETQFYPS RLLSILLITV LKTAFGFVNN PSSITVTIPL GSDSNYRDRI
     KDILRHALNK VANPDIPSTT LIRLIEEPTA VVASYAHRLN LHPKGDVVLS FCMGSGYLQA
     ELVYIQKKTD HWTIHKIPDI QAVYVENKAG NYIDQLIFEY LMKIVRKRSK NKSLRLSPKP
     EKRLRIACEK LKCALSFAPH TRVDVDSLYR NKAGQDCDLL EVVQRQDVEQ IYDKIISDHI
     GKIVRMTGVI QPKFILMGGG STRIPKINEY LQKNFKDSKI GNFMNVDEVA STGAATIASD
     SVMVAEPINS PTILKLIKDR KEVSTSPEKE IIMNTKDPIP KPQDSMQEVR TNQNSQNDER
     IVEQPSRPIT HPPTVVPTES RSTNREDVAS EEISQNPPTN SAQTQIIAHM NQEQRNHAYF
     PTAMEKPNHY FSNPQIPSQS KPGYEEQKKI KKNHKILKNV IHPTPDYDHN PKPKSDNVVM
     KERSNPEISE PDYDEKPKPE NISVIHPVVM KILVNPAPDY EPTKKLKNND VMTNKQSNPE
     ISEPDYEKTE SEDTRVVNPP IMKILANLKP DYEPIKKPKT NDMTMKEQPK PEENTPIMSK
     IEPTEEKRPS SPSIIAELKQ NEGEISSKRT ETIANDRYPV NYTHTPIDIE LMNVISPRSP
     NNSYPRKPTH EANGDILDRN EIQYPNADLP TKSSLPRNRA YGTQAYPIPS QSSVYGHQLS
     PYSLQYSCKN AQGYSLPINI SYSNPKDHKY TERAEKKTNK HRNESEKTSA KKYKDSKPEI
     KPEKLNWTLS NNNCHYIEIP FQITKLGEKL KFPIGGKHSK YFDGFAFKLF RRQLVYILSS
     KK
//