ID A0A2A2L9C7_9BILA Unreviewed; 707 AA.
AC A0A2A2L9C7;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=carboxylesterase {ECO:0000256|ARBA:ARBA00039155};
DE EC=3.1.1.1 {ECO:0000256|ARBA:ARBA00039155};
GN ORFNames=WR25_24708 {ECO:0000313|EMBL:PAV82754.1};
OS Diploscapter pachys.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Diploscapter.
OX NCBI_TaxID=2018661 {ECO:0000313|EMBL:PAV82754.1, ECO:0000313|Proteomes:UP000218231};
RN [1] {ECO:0000313|EMBL:PAV82754.1, ECO:0000313|Proteomes:UP000218231}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PF1309 {ECO:0000313|EMBL:PAV82754.1};
RA Fradin H., Zegar C., Gutwein M., Lucas J., Kovtun M., Corcoran D.,
RA Baugh L.R., Kiontke K., Gunsalus K., Fitch D.H., Piano F.;
RT "Genome architecture and evolution of a unichromosomal asexual nematode.";
RL Curr. Biol. 0:0-0(2017).
CC -!- SIMILARITY: Belongs to the type-B carboxylesterase/lipase family.
CC {ECO:0000256|ARBA:ARBA00005964}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAV82754.1}.
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DR EMBL; LIAE01007028; PAV82752.1; -; Genomic_DNA.
DR EMBL; LIAE01007028; PAV82754.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A2L9C7; -.
DR Proteomes; UP000218231; Unassembled WGS sequence.
DR GO; GO:0052689; F:carboxylic ester hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0008234; F:cysteine-type peptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR CDD; cd02248; Peptidase_C1A; 1.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 2.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR002018; CarbesteraseB.
DR InterPro; IPR019826; Carboxylesterase_B_AS.
DR InterPro; IPR019819; Carboxylesterase_B_CS.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR000668; Peptidase_C1A_C.
DR InterPro; IPR039417; Peptidase_C1A_papain-like.
DR PANTHER; PTHR11559; CARBOXYLESTERASE; 1.
DR PANTHER; PTHR11559:SF418; CARBOXYLIC ESTER HYDROLASE; 1.
DR Pfam; PF00135; COesterase; 2.
DR Pfam; PF00112; Peptidase_C1; 1.
DR PRINTS; PR00705; PAPAIN.
DR SMART; SM00645; Pept_C1; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR PROSITE; PS00122; CARBOXYLESTERASE_B_1; 1.
DR PROSITE; PS00941; CARBOXYLESTERASE_B_2; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000218231};
KW Serine esterase {ECO:0000256|ARBA:ARBA00022487}.
FT DOMAIN 470..695
FT /note="Peptidase C1A papain C-terminal"
FT /evidence="ECO:0000259|SMART:SM00645"
FT REGION 449..472
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 707 AA; 80041 MW; 296E22CF0F907296 CRC64;
MMAWMLRYKY ARRKDPEGLI DAMNYGSKCS QSNFTNEDCL FINIFTPLLD LEIKSEDSRF
FTSKDDTIPG NYAISDMTEA LQWTKRYIKF FGGDPNRITI CGQSSGAESQ ILRCMRSATA
TELQNADMHL PYSHFMQWGT VIDKVYLPDA VENLAMKRPP LSVMGGVTAG EWLLFEQGNI
RDHLKSDAYM RQGIIHRLRD LYEMKCWNNY DAILQRTISH YIDSQKVPDD DHVVMAGIWI
KLMSDLDFTA AVLRDLKYFA TTGSAAYLYS FDYLSPLAWS WLNVTELRLA PHSSDKSYLY
EEGCKGYKCQ DEDIALRDTI QRCWVNFVLT GNPTPISSGL PFIWPKLDGS NRYVSVMPSP
ENDSRAKLQN VLKNDRHFQK LRNKFKNLKT DPILDFLRYE KYSEVKKEVD THNEKFGKGE
TTYKAEVNKF TVASEDELPP FTLKMPPSST VFIKDSGKRQ KRDENSTSSL SDSVDWRPFM
KPILDQESCG GCWAFAMLGM LEGFLKINEK DLSPLSVQQL LDCDRATDSK YGLANGGCDG
GYFQVASNFL KNNFVTSGSD YPFTGSSGPS SACITGLPFI SPKIITFDTG YVSMSQINND
SIVKLEKDME DRVRKGPVAV GLATASAMFS YGSGIYDGQC GSSINHAVVI VGFTPDYWII
RNSWGADFGE EGHIRLARKA GSDACMIYRY WAQALKVFYR RFRIAGC
//
