ID A0A2A2LA56_9BILA Unreviewed; 450 AA.
AC A0A2A2LA56;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE RecName: Full=Major sperm protein {ECO:0000256|RuleBase:RU003425};
GN ORFNames=WR25_01891 {ECO:0000313|EMBL:PAV83008.1};
OS Diploscapter pachys.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Diploscapter.
OX NCBI_TaxID=2018661 {ECO:0000313|EMBL:PAV83008.1, ECO:0000313|Proteomes:UP000218231};
RN [1] {ECO:0000313|EMBL:PAV83008.1, ECO:0000313|Proteomes:UP000218231}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PF1309 {ECO:0000313|EMBL:PAV83008.1};
RA Fradin H., Zegar C., Gutwein M., Lucas J., Kovtun M., Corcoran D.,
RA Baugh L.R., Kiontke K., Gunsalus K., Fitch D.H., Piano F.;
RT "Genome architecture and evolution of a unichromosomal asexual nematode.";
RL Curr. Biol. 0:0-0(2017).
CC -!- FUNCTION: Central component in molecular interactions underlying sperm
CC crawling. Forms an extensive filament system that extends from sperm
CC villipoda, along the leading edge of the pseudopod.
CC {ECO:0000256|ARBA:ARBA00037744, ECO:0000256|RuleBase:RU003425}.
CC -!- SUBCELLULAR LOCATION: Cell projection, pseudopodium
CC {ECO:0000256|ARBA:ARBA00037818}. Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAV83008.1}.
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DR EMBL; LIAE01007005; PAV83008.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A2LA56; -.
DR STRING; 2018661.A0A2A2LA56; -.
DR Proteomes; UP000218231; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0031143; C:pseudopodium; IEA:UniProtKB-SubCell.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR000535; MSP_dom.
DR InterPro; IPR008962; PapD-like_sf.
DR PANTHER; PTHR22920; MAJOR SPERM PROTEIN; 1.
DR PANTHER; PTHR22920:SF21; MAJOR SPERM PROTEIN; 1.
DR Pfam; PF00635; Motile_Sperm; 1.
DR SUPFAM; SSF49354; PapD-like; 1.
DR PROSITE; PS50202; MSP; 1.
PE 4: Predicted;
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212,
KW ECO:0000256|RuleBase:RU003425};
KW Reference proteome {ECO:0000313|Proteomes:UP000218231}.
FT DOMAIN 329..450
FT /note="MSP"
FT /evidence="ECO:0000259|PROSITE:PS50202"
FT REGION 158..311
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 170..192
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 231..254
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 262..311
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 450 AA; 50557 MW; 339FE43C181F41FE CRC64;
MACGGIANEG FDPSTVFEKA SGWVKERVHD ERHFTARWLK QIEEATGVNR CIIAQSVAGI
VTLSLCCAQQ PFFICNGVLV AFPCILLFVY PEECPKKEHL TIYWVCFGIL TALDGALKKL
PGYYHIKLLL MLLLFVEPFR LVDKIEKIAE EANRRNNCEN TNDATRTAKS DVMRATKMKS
SPKEEKKKEE SAAQPAPPSQ ETLALPPEPL NGPEQRPAEA APAPVSEENK PAEASKVDSR
EKEPIKEEVK QENEMPKGLL SPSIITDQSR TETKSPTQKT AVESFSTTDI PGNSRFRGEN
PMTNNRSYRL PLTPGVDNKD IEPANNLRDL IVFPTEKIVF NAPFDFDNIT YHIKVTNNSL
HRMAFAIKCN CIPRIICYPP HGILASKETI AVAVTCQKIL EFSEGVVKDD RIAIEYVIMS
NKDQRKEFTF ELLHSSETRC RKNLAIEYNP
//
