ID A0A2A2LBY7_9BILA Unreviewed; 860 AA.
AC A0A2A2LBY7;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 22-FEB-2023, entry version 11.
DE RecName: Full=AP complex subunit beta {ECO:0000256|PIRNR:PIRNR002291};
GN ORFNames=WR25_13322 {ECO:0000313|EMBL:PAV83756.1};
OS Diploscapter pachys.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Diploscapter.
OX NCBI_TaxID=2018661 {ECO:0000313|EMBL:PAV83756.1, ECO:0000313|Proteomes:UP000218231};
RN [1] {ECO:0000313|EMBL:PAV83756.1, ECO:0000313|Proteomes:UP000218231}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PF1309 {ECO:0000313|EMBL:PAV83756.1};
RA Fradin H., Zegar C., Gutwein M., Lucas J., Kovtun M., Corcoran D.,
RA Baugh L.R., Kiontke K., Gunsalus K., Fitch D.H., Piano F.;
RT "Genome architecture and evolution of a unichromosomal asexual nematode.";
RL Curr. Biol. 0:0-0(2017).
CC -!- SIMILARITY: Belongs to the adaptor complexes large subunit family.
CC {ECO:0000256|ARBA:ARBA00006613, ECO:0000256|PIRNR:PIRNR002291}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAV83756.1}.
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DR EMBL; LIAE01006928; PAV83755.1; -; Genomic_DNA.
DR EMBL; LIAE01006928; PAV83756.1; -; Genomic_DNA.
DR EMBL; LIAE01006928; PAV83757.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A2LBY7; -.
DR Proteomes; UP000218231; Unassembled WGS sequence.
DR GO; GO:0030131; C:clathrin adaptor complex; IEA:InterPro.
DR GO; GO:0030276; F:clathrin binding; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR Gene3D; 2.60.40.1150; -; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR Gene3D; 3.30.310.10; TATA-Binding Protein; 1.
DR InterPro; IPR026739; AP_beta.
DR InterPro; IPR016342; AP_complex_bsu_1_2_4.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR015151; B-adaptin_app_sub_C.
DR InterPro; IPR002553; Clathrin/coatomer_adapt-like_N.
DR InterPro; IPR008152; Clathrin_a/b/g-adaptin_app_Ig.
DR InterPro; IPR013041; Clathrin_app_Ig-like_sf.
DR InterPro; IPR013037; Clathrin_b-adaptin_app_Ig-like.
DR InterPro; IPR009028; Coatomer/calthrin_app_sub_C.
DR InterPro; IPR012295; TBP_dom_sf.
DR PANTHER; PTHR11134; ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER; 1.
DR PANTHER; PTHR11134:SF3; AP COMPLEX SUBUNIT BETA; 1.
DR Pfam; PF01602; Adaptin_N; 1.
DR Pfam; PF02883; Alpha_adaptinC2; 1.
DR Pfam; PF09066; B2-adapt-app_C; 1.
DR PIRSF; PIRSF002291; AP_complex_beta; 1.
DR SMART; SM00809; Alpha_adaptinC2; 1.
DR SMART; SM01020; B2-adapt-app_C; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF49348; Clathrin adaptor appendage domain; 1.
DR SUPFAM; SSF55711; Subdomain of clathrin and coatomer appendage domain; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR002291};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|PIRNR:PIRNR002291};
KW Reference proteome {ECO:0000313|Proteomes:UP000218231};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR002291}.
FT DOMAIN 633..740
FT /note="Clathrin adaptor alpha/beta/gamma-adaptin appendage
FT Ig-like subdomain"
FT /evidence="ECO:0000259|SMART:SM00809"
FT DOMAIN 749..860
FT /note="Beta-adaptin appendage C-terminal subdomain"
FT /evidence="ECO:0000259|SMART:SM01020"
FT REGION 480..503
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 860 AA; 94032 MW; 64F4CD58940A4EFD CRC64;
MGCIRVEKIT EYLCEPLRKC MKDEDPYVRK TAAVCVAKLY DMNPNLVEEQ GFVELLNDLL
SDANPMVVAN AVAALTEINE QKPLIEVNSQ MVNKLLTALN ECTEWGQVFI LDALAGYRPK
DEREAQNICE RISPRLAHAN AAVVLSTVKV LMKLVDLLPN DSDFIAQLTK KLAPPMVTLL
SAEPEIQYVA LRNINLIVQK RPDILKQEMK VFFVKYNDPI YVKMEKLDIM IRLAQQRNIA
QVLSELKEYA TEVDVDFVRK SVRAIGRCAI KVEASAERCV ATLLELIQTK VNYVVQEAVV
VIKDIFRKYP NRYESIISTL CENLDTLDEP EARASMIWII GEYAERIDNA DELLESFVEG
FHDENTQVQL QLLTAVVKLF LKRPADTQQL VQRVLSLATQ DSDNPDLRDR GYIYWRLLSA
DPAAAKQVVL AEKPLISEET DLLEPSLLDQ LVCHIGSLAS VYHKPPSAFV DTARQPLRTL
TAPNTNGHPV DNSTSAVSRS QQPTVIPSQD TMIADLLSLD LNAPAVAPGG TYGQTAPMGY
GASGGGLDDL LGLGGSDSIM GGGAPAPAQA SNAPFASSTF DPLAGLGLGA PAQPAAPVAA
APIGGADLGG LADIFGGASG LGGVATSAGF QMPKQMWLEA SKAKGLQVEG TFVRRSGRVY
MEITLTNKAM QAMSGFAVQF NKNSFGLMPA EPLNVPAPLL PSQNITVSMA CDTSGPVQKM
EPLTNLQVAI KNDIEVFYFA CAVPLLVYFQ EAGPMEKREF LEMWKDIPEQ NEQQFTIPNP
HGLSADAICA KLQTSNICTV ARRSVEGQEL LYHSIKYTNS IYVLSELKLN LGSPTLTLSL
KSRHVTAISN LNEMYQMILN
//
