ID A0A2A2LN43_9BILA Unreviewed; 1176 AA.
AC A0A2A2LN43;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=FAD dependent oxidoreductase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=WR25_19098 {ECO:0000313|EMBL:PAV87673.1};
OS Diploscapter pachys.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Diploscapter.
OX NCBI_TaxID=2018661 {ECO:0000313|EMBL:PAV87673.1, ECO:0000313|Proteomes:UP000218231};
RN [1] {ECO:0000313|EMBL:PAV87673.1, ECO:0000313|Proteomes:UP000218231}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PF1309 {ECO:0000313|EMBL:PAV87673.1};
RA Fradin H., Zegar C., Gutwein M., Lucas J., Kovtun M., Corcoran D.,
RA Baugh L.R., Kiontke K., Gunsalus K., Fitch D.H., Piano F.;
RT "Genome architecture and evolution of a unichromosomal asexual nematode.";
RL Curr. Biol. 0:0-0(2017).
CC -!- SIMILARITY: Belongs to the GcvT family.
CC {ECO:0000256|ARBA:ARBA00008609}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAV87673.1}.
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DR EMBL; LIAE01006554; PAV87673.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A2LN43; -.
DR STRING; 2018661.A0A2A2LN43; -.
DR Proteomes; UP000218231; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 2.40.30.110; Aminomethyltransferase beta-barrel domains; 1.
DR Gene3D; 3.30.70.1400; Aminomethyltransferase beta-barrel domains; 1.
DR Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR006076; FAD-dep_OxRdtase.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR032503; FAO_M.
DR InterPro; IPR028896; GCST/YgfZ/DmdA.
DR InterPro; IPR013977; GCV_T_C.
DR InterPro; IPR006222; GCV_T_N.
DR InterPro; IPR029043; GcvT/YgfZ_C.
DR InterPro; IPR027266; TrmE/GcvT_dom1.
DR PANTHER; PTHR43757; AMINOMETHYLTRANSFERASE; 1.
DR PANTHER; PTHR43757:SF9; SARCOSINE DEHYDROGENASE; 1.
DR Pfam; PF01266; DAO; 1.
DR Pfam; PF16350; FAO_M; 1.
DR Pfam; PF01571; GCV_T; 1.
DR Pfam; PF08669; GCV_T_C; 1.
DR SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF103025; Folate-binding domain; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000218231}.
FT DOMAIN 340..703
FT /note="FAD dependent oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF01266"
FT DOMAIN 707..762
FT /note="FAD dependent oxidoreductase central"
FT /evidence="ECO:0000259|Pfam:PF16350"
FT DOMAIN 765..1041
FT /note="Aminomethyltransferase folate-binding"
FT /evidence="ECO:0000259|Pfam:PF01571"
FT DOMAIN 1067..1149
FT /note="Glycine cleavage T-protein C-terminal barrel"
FT /evidence="ECO:0000259|Pfam:PF08669"
FT REGION 106..131
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1176 AA; 132097 MW; 24A4677992CFC1CE CRC64;
MAARVKNCSH RTRRARNTRF VHRTMAPSKK NRTAVSAPGC SDVVEVTTDE VFKLYERAKD
YHRKGDKENA YSLLKNLLPF FTSDPAYWVR VTELEIDYIY GENSSASTSE ENRSANESSG
NNTPNNRMNI TKDDVARSSQ LALCLAKGTD DKKLITTATL LNAFLAIEQF RFRYALELLE
QIPESWWSCM SMNDKQTANK YETICKKETQ TTSSKPDESQ SSRMTDLKGK LIDSDGMRII
EECRTAFQNG NKKEALQIFK KYHETHPDLH QLLVYFGYDL YVKGSDSEGA SKLMKQYSHL
NFKQEISRMV VSRLLLLTAS RSSQTALIRR LSTKYASQAD VVVCGGGIAG SSVAYHLAKR
GKKVFLFERD VVGCGGATGL ASGLVTASMY WQDPTNQIIA DRSIRMYTEL SKEATFKFTK
CGRLYLASSL SSEILLRRMY SRGVLHHDDV ELIDDQSEML SRWPFLQTED IQLALYSPED
LVVDAAALCL EIANKAKYYG ATIFENCEVL EVLLGDDGQV YAVKTTNGLV ETKQFVDASG
VWTGTVLVKP LPHRHVQTAA YPCTYTSIHT AKLPTGAVGD HTPIINDMDG NVMLHATSYN
TIASGFNEES IRAMAKQGTN VGLWHHPEPD WDRFASNLER LVHRFPMLSE VDSGDLICGM
EAYTPDKVPT IGESSQARGY YVMNGMNGQG LSLAGGLGEL LATWIVEGQP DLDVARLDVG
RFIELHANPR YLMERTPEVA TMTYRNLYNS YQCHSARNLR MSPIYYQLKD AGAVFGEIMG
YERPLWFDKY SKPDHHSLMM GQDTLIGKPS WFDSVRAEYE ACRERVGLID MSSFSKFDIE
GPDAVKLLQY LCSANIDRPI GTTVYTGMQH EKGGYVTDCT LSRLGTNKFF MVAPTIQQER
VMTWMKKWAE KMNANVHAVD VTGGYTALDC VGPSSRYLMQ DITGLSMSST DFPSFHCQEI
DIGMATGIRA ISVTHCGELG WVMYIPNEVA QNVYEKIVDA GREYSMLHAG YYTLRQLRIE
KFYVYWGQDI NATVTPVECG RAFRVDFKKD FIGKAALEAQ IERGVHKKFV QLLIDKHDLN
TDPWPQGGET LFRNGQPVGL TTSAAYGFTL GCQVCIAYVE NRDFGVSPDF IAKGNYELDI
AGKRFPVRMN LHSPSLPMIS SEHPLHYRPT QDSDID
//
