ID A0A2A2LNG4_9BILA Unreviewed; 2176 AA.
AC A0A2A2LNG4;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=PHD-type domain-containing protein {ECO:0000259|PROSITE:PS50016};
GN ORFNames=WR25_04812 {ECO:0000313|EMBL:PAV87595.1};
OS Diploscapter pachys.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Diploscapter.
OX NCBI_TaxID=2018661 {ECO:0000313|EMBL:PAV87595.1, ECO:0000313|Proteomes:UP000218231};
RN [1] {ECO:0000313|EMBL:PAV87595.1, ECO:0000313|Proteomes:UP000218231}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PF1309 {ECO:0000313|EMBL:PAV87595.1};
RA Fradin H., Zegar C., Gutwein M., Lucas J., Kovtun M., Corcoran D.,
RA Baugh L.R., Kiontke K., Gunsalus K., Fitch D.H., Piano F.;
RT "Genome architecture and evolution of a unichromosomal asexual nematode.";
RL Curr. Biol. 0:0-0(2017).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAV87595.1}.
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DR EMBL; LIAE01006559; PAV87595.1; -; Genomic_DNA.
DR Proteomes; UP000218231; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd15512; PHD4_KMT2C_like; 1.
DR CDD; cd15513; PHD5_KMT2C_like; 1.
DR CDD; cd15514; PHD6_KMT2C_like; 1.
DR Gene3D; 2.30.30.1150; -; 1.
DR Gene3D; 3.30.160.360; -; 1.
DR Gene3D; 1.10.30.10; High mobility group box domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 3.
DR InterPro; IPR003888; FYrich_N.
DR InterPro; IPR036910; HMG_box_dom_sf.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR45888; HL01030P-RELATED; 1.
DR PANTHER; PTHR45888:SF6; HL01030P-RELATED; 1.
DR Pfam; PF05964; FYRN; 1.
DR Pfam; PF00628; PHD; 2.
DR SMART; SM00541; FYRN; 1.
DR SMART; SM00249; PHD; 5.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 3.
DR PROSITE; PS51542; FYRN; 1.
DR PROSITE; PS50016; ZF_PHD_2; 3.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000218231};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 351..406
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 403..453
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 478..533
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT REGION 95..148
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 165..275
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 609..632
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 649..694
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 809..928
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 993..1048
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1452..1489
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1124..1154
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 95..144
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 165..184
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 650..675
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 676..693
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 809..885
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 909..927
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1007..1040
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2176 AA; 240043 MW; AD7349820839940E CRC64;
MMCIECGGAV KGSAEVCDSC NGVGPDSSSS VSMMTVGPSM SCSMCGLLVD MRHTQARMCT
TCNKYVHTSC DSSEGGLDGF TCAMCRRSPL VQDVMLSGMS NPSPGHEEQN TNTTSGVSSS
MAGSSDMAPP TSYHSNNSPP LPSGGVTSGV GAEFTDVYNL SEGIASPATT SDSARNSPFY
PENSSSDIDE DFVPASVRGG YRGRGAKKKP GVRGSSTSKR GAGKPPNIFT GEKSGTIPGT
TRGKRGGRGS RGGSQQANKG VGRGRGRGRS SASSYASAII QGQQNAKMLL NEFFQNNAYH
NQFQNTVQSN VREVDEAMIV DEEERHAKSE DAEYVRTVVL CEQDDEFLQK ACLCLVCGSV
GKGPESSMVA CSNCAQTYHT YCVGLHDKLN NAVVCRGWRC LDCTVCEGCG KGEDESKLLL
CEECDISYHI YCLTPRLERI PQGPWRCQWC ARCRRCNVRV ASGLDLTKDG LCLACHSMRK
CPKCVRAYNV GDKIIRCSSC LKWYHGTCED LYNDEMLEQA AQGRMRCTAC RPSTKNFANF
MPFGADSHNV VVCDNVALNK AAEEVLGSKF MPSVIRPNPL ESMYGGYHRS DSFDHFGSID
EEYQPEEFEP IISSSGRGRG SGRGGGPGRR LTKIGVGGFV VKQARNRLVQ NEDEVSSSSA
SVGGNSNSNG PTQGPEDEGK KQRKPRKPRK SFLEDAYPAI IQENFFGMKA VEGKNLIEVT
LDEPHLMEQS SGRNGHADGH NGHELSYEAT EMLRNDMTEN DILESMDLRD LDMDVNTMDF
SMLMEDEEDE AFDDSLYLND AIDLVRSDAN FGNTNQQPPS SNQGPSTSQQ HPAGPMQSQQ
GMHPGQANLN QHHHDFQNGP HQMHPNQHQM PHMVQQQQQK PSMYGQPGMD MQPQMGQDNA
GMPGQNMPPA LVRTSSDQGL DANNDKSNSA RWLEDEPLGL GATIAAVLYV NSEHSYLKEQ
YPEINERIKQ MHKLWRQLDA ERRQHYVLRA RQNRTDRGCR RARRVGSTAR VSSQSSSVDS
PTVSSPTGNI FSQQPQPGRP QMMSPVDGLP ERFKVPPIPP GGMPPMPQGY YVQPPQQKME
SNGVRMQSLL EQSQLQRTLS HLPEEMTEQY RLMGEKTQDL LKRQEGVESD LARLRKQKKT
LAAKKRQMQK QQAAAVAAAG GPEISVGMNG PEGTMMGQVG QMNQNPMTQA GQTSEPLPTP
PAADFDLSDE EKQCLTQLQT QISARQKDLE NVKRELKNHQ GIMFEFESKY HITRPMVGGN
GVPIGAGTDA LHQPGSTPVG IALRGAISGN ASGLMGAQMG GPGGIGPPPY GSLMHPPANL
MQQGAQPMRV PQQMPYGSIM NNLESQRRIA AIHQGAPPGA FSGALPPHQH SRMPWGMMLK
PYSMSLGGIP YERLTSPVEK EIYECLDDVI HKITIDFDGR DPAREMIPPY HPMQSQPAGS
GMLKRLLDPG LGPMQLPPHM MSSSLADPLE PPKPKKKRQM QKKPGPSALE NQYDIMVERV
NAQLKNCERL PKRAQEPSPR NPGAVFAVMG ISDLTNRAEK RALLGDTIGQ MQLSFMDDYF
GGEERKVGSK WLFCPPPSMA EVSPDTNLVR LTQIEMPQEQ EIFTDKEDAI WQPYDVLASF
SDYIERCEKS EHIRVRCRIT ECPPPPEPHR RAFYQKIEQP DEVEVSLLVQ ENEERSLPET
IEDLKRILDV GEMDYQLDTP PLSPLESKNH NDYGTATDRI ESEQQVKLTA IVKEEPLNPS
TSDADACRTC HRAITKPVIV QKASAMGIRL HDDSRDDATV QFCSGKCYYV MMAQNKVILS
ADQLAAAEGQ ADEETMGRLK QIHAENLAKC INQGKSRMDL PLTPIFSDAL LTSPRDSRYG
LDDGKRDLVK TIRVCELSQL QGEQQRRTGS RAAGEEWKVY SKEILASFLR INTIKKELAL
SAKLGVALPS PSITDRRRCV LCGQSGDGET SICGRLLNYE IYWVYENPQG GLEHVETAIV
RSLTTSCEFC RRFGATLKCY KVGCETNFHI PCAKAMAGAK FIKDRTFICP KHTDVNPEVV
VTNLETLRRV YIVKNENALL AKLFEINDDM HKNKFVLKLG ALTFHQIGQL LPEQLKTFHN
ATYLFPVGYT VARWFWSPND AKVRVQFTCK IQDGNGRPKF VVSMGDEKTW EGESASGKEI
SFDLSGLSIF IGNNCL
//
