ID A0A2A2LRI6_9BILA Unreviewed; 1014 AA.
AC A0A2A2LRI6;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Helicase ATP-binding domain-containing protein {ECO:0000259|PROSITE:PS51192};
GN ORFNames=WR25_12076 {ECO:0000313|EMBL:PAV88823.1};
OS Diploscapter pachys.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Diploscapter.
OX NCBI_TaxID=2018661 {ECO:0000313|EMBL:PAV88823.1, ECO:0000313|Proteomes:UP000218231};
RN [1] {ECO:0000313|EMBL:PAV88823.1, ECO:0000313|Proteomes:UP000218231}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PF1309 {ECO:0000313|EMBL:PAV88823.1};
RA Fradin H., Zegar C., Gutwein M., Lucas J., Kovtun M., Corcoran D.,
RA Baugh L.R., Kiontke K., Gunsalus K., Fitch D.H., Piano F.;
RT "Genome architecture and evolution of a unichromosomal asexual nematode.";
RL Curr. Biol. 0:0-0(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAV88823.1}.
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DR EMBL; LIAE01006491; PAV88823.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A2LRI6; -.
DR STRING; 2018661.A0A2A2LRI6; -.
DR Proteomes; UP000218231; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0010467; P:gene expression; IEA:UniProt.
DR GO; GO:0090304; P:nucleic acid metabolic process; IEA:UniProt.
DR CDD; cd18021; DEXHc_Brr2_2; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 2.
DR Gene3D; 2.60.40.150; C2 domain; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 1.10.3380.10; Sec63 N-terminal domain-like domain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004179; Sec63-dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR24075; SEC63 DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR24075:SF5; U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 200 KDA HELICASE; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF02889; Sec63; 2.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00973; Sec63; 2.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR SUPFAM; SSF158702; Sec63 N-terminal domain-like; 2.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022806};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022806};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022806};
KW Reference proteome {ECO:0000313|Proteomes:UP000218231}.
FT DOMAIN 222..397
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
SQ SEQUENCE 1014 AA; 115606 MW; BAE440C9F0DA8203 CRC64;
MVTARQWQSL NPLHQFKKIP AEVVRSIDKK NISFDRLYDL DQHQLGDLIK MPKMGKPLYK
FIRQFPKLEM QTLIQPITRT TLRIELTITP DFQWDEKVHG SAEGFWIFVE DVDGELILHH
EYFLLKQKFA TDEHVVKMFV PVFDPMPPLY FVRIVSDRWL GSETVLPISF RHLILPEKYP
PPTELLDLQP LPISALNNKD FEEVFKTAGI SVFNPIQTQV FRTIYENKEN VLLAAPEGSG
KTACAELAIL RHFEHHPESK AVYVTPMEDM AIKVYQDWAQ RIGKILDIEV VMLSGEPSTD
LKLIQRGKLI VSVPERWDNV SRRWKQRKNV QAVKLFVVDD LHMIGSTNGP VLEVICSRMR
YMSAQLENSV RIIALSSSLT NAKDVGAWLG APASGTFNFL PNTRPVPLEL YIQGFNLSHN
ASRLAAMVRP VYQAITRHAG KLRPKPALVF VPGRRQSRST AVDLLTMAHA DGSPQRFLHI
NESDPNFGIL LEKLQDKTLK ETLSCGVGYL HEGTSQKDMA IVEELFNLGA IQICIVPRSM
CFQIKMFAYL VVIMDTQFYN GKFHVYEDYP VGDVLHMVGL ANRPNQDSDA KCVLMCQSSK
KDFFKKFLYE PLPVESHLDH CLHDHFNAEI VTKTIENKQD AIDYLTWTFL YRRMTQNPNY
YNLQGVTHRH LSDALSELCI AIKDDMDTLP LNLGMIAAYY YISYTTIELF SMSLQAKTKL
RALIEIISNA SEFANVPMRH REDVILRQLA DKLQGQMKNQ KFTDPHVKVN LLLHAHLSRI
QLSAELNKDT EVVVLKAIRL VQACVDVLSS NGWLSPAIHA MELSQMLTQA VYSSESYLKQ
LPHCTNSLLE RAKEKKVESI FELLELDDDV RGEILQMEDA ELADVAKFCN NYPSIEVEHE
LSAETVKESE QIVVMVSMER ENHVDGLAPP VVAPLFPQKR KEEGWWLVVG DPTNNTLYSI
KRLTINEAAK MQLDFVLPNS GTYDLKLYFI CDSYMKAVLA SVAIVTNKAQ SVEG
//
