ID A0A2A2M063_9BILA Unreviewed; 1243 AA.
AC A0A2A2M063;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=Myosin motor domain-containing protein {ECO:0000259|PROSITE:PS51456};
GN ORFNames=WR25_20112 {ECO:0000313|EMBL:PAV91617.1};
OS Diploscapter pachys.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Diploscapter.
OX NCBI_TaxID=2018661 {ECO:0000313|EMBL:PAV91617.1, ECO:0000313|Proteomes:UP000218231};
RN [1] {ECO:0000313|EMBL:PAV91617.1, ECO:0000313|Proteomes:UP000218231}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PF1309 {ECO:0000313|EMBL:PAV91617.1};
RA Fradin H., Zegar C., Gutwein M., Lucas J., Kovtun M., Corcoran D.,
RA Baugh L.R., Kiontke K., Gunsalus K., Fitch D.H., Piano F.;
RT "Genome architecture and evolution of a unichromosomal asexual nematode.";
RL Curr. Biol. 0:0-0(2017).
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|PROSITE-ProRule:PRU00782}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00782}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAV91617.1}.
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DR EMBL; LIAE01006301; PAV91617.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A2M063; -.
DR STRING; 2018661.A0A2A2M063; -.
DR Proteomes; UP000218231; Unassembled WGS sequence.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0032982; C:myosin filament; IEA:UniProtKB-KW.
DR GO; GO:0030017; C:sarcomere; IEA:UniProt.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:InterPro.
DR Gene3D; 1.10.287.1490; -; 1.
DR Gene3D; 1.20.5.340; -; 4.
DR Gene3D; 1.20.5.370; -; 2.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 6.20.240.20; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR Gene3D; 4.10.270.10; Myosin, subunit A; 1.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR002928; Myosin_tail.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014751; XRCC4-like_C.
DR PANTHER; PTHR45615; MYOSIN HEAVY CHAIN, NON-MUSCLE; 1.
DR PANTHER; PTHR45615:SF58; MYOSIN-4; 1.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF01576; Myosin_tail_1; 2.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF90257; Myosin rod fragments; 4.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF57997; Tropomyosin; 1.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|PROSITE-ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175};
KW Muscle protein {ECO:0000256|ARBA:ARBA00023179};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000218231};
KW Thick filament {ECO:0000256|ARBA:ARBA00022433}.
FT DOMAIN 1..210
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT REGION 85..107
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT REGION 340..377
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 440..526
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 542..574
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 746..767
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1188..1243
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 349..377
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 746..760
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1189..1207
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1208..1243
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1243 AA; 142715 MW; 8B5D4F8BDCDEC3D7 CRC64;
MRHYAGTVRY NVLNWLEKNK DPLNDTVVSV MKATTGNALL NVIWEDYTTQ EEAAQKAKEG
GGGGGKKKGK SGSFMTVSMM YRESLNNLMT MLHKTHPHFI RCIIPNEKKQ SGLIDAALVL
NQLTCNGVLE GIRICRKGFP NRTLHQDFVQ RYAILAAAEA KSNDDKKKCA EAIMSKLINE
GVLSEENFRI GLTKVFFKAG VLAHLEDVRD EKLSVIITGF QSQIRWYLGL TERKRRMEQR
AGLLIVQRNV RSWCTLRTWE WFKLYGKVKP MLKAGKEAEE LEKMNDKMKE LQENLAREEK
LRKELEDSST KLLEEKNQLF TSLESTKGQL SDAEERLAKL QSQKNDADRQ LTDLNDRLAD
TEDRNADIQR AKKKVESEVE SLKKQIQDLE NSLRKAESEK QSKDHQIRSL QYEMQQQDEA
IAKLNKEKKH QEEINRKLME DLQSEEDKTN HTNKIKQKLE STLDDLEDSL EREKRSRADL
DKQKRKVEGE LKIAQENIEE GGRQRHDLEN NLKKKESELH SVSSKLEDEQ ALVAKLQRQI
KEEQSRISEL EEELENERQS RSKADRARAD AQRELEELGE RLDEQGGATA AQVEINKKRE
AELAKLRRDL EEANMNHESQ LGVLRKKHTD AVAELTDQLD QINKTKQKLE KDRAQAVRDA
EELASQLDSE TSGKMNNEKL AKQFELQLSE LQSKCDEQSR QLMDFTSMKG RMHNENGDLV
RQLEDAESQV NQLSRLKAQL TSQLEEAKRT ADEESRERQT LAAQAKNYQH EAEQLQESLE
EEIEGKNEVL RQLSKANAEI QQWKAKFEGE GLIKADELED AKKRQGNKIQ ELTEALDAAN
SKIASLEKTK GRLVGDLDDA QVDVERANSY SASLEKKQKG FDRTIDEWKK KVDDLNAELD
NVQRELRNAS TDLFKAKNSQ EEAAEVVEGL RRENKNLAQE IKDLADQLGE GGRSHALDEA
EAALEAEESK VLRAQVEVSQ IRSEIEKRIQ EKEEEFENTR KNHQRAMDSM QASLETEAKG
KAELLRADLD ETLSEYKAAE ERSKKAIADA TKLAEDLRQE QEHAQHIDRM RKGLEQQLKE
IQVRLDEAEA AALKGGKKVI AKLEQRVREL ETELDGEQRR CQEANKNMQK VDRRARELQF
QVDEDKKNFE RLQDLIDKLQ NKLKTQKKQI EEAEEVANTN LQKYKQLTNQ LEDAEERADD
AENSLSKMRT KSRSSTSVAP AGLQTSASAM VMRSPSRSRN TDF
//
