ID A0A2A2M0A7_9BILA Unreviewed; 872 AA.
AC A0A2A2M0A7;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:PAV91924.1};
GN ORFNames=WR25_06225 {ECO:0000313|EMBL:PAV91924.1};
OS Diploscapter pachys.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Diploscapter.
OX NCBI_TaxID=2018661 {ECO:0000313|EMBL:PAV91924.1, ECO:0000313|Proteomes:UP000218231};
RN [1] {ECO:0000313|EMBL:PAV91924.1, ECO:0000313|Proteomes:UP000218231}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PF1309 {ECO:0000313|EMBL:PAV91924.1};
RA Fradin H., Zegar C., Gutwein M., Lucas J., Kovtun M., Corcoran D.,
RA Baugh L.R., Kiontke K., Gunsalus K., Fitch D.H., Piano F.;
RT "Genome architecture and evolution of a unichromosomal asexual nematode.";
RL Curr. Biol. 0:0-0(2017).
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
CC -!- SIMILARITY: Belongs to the WD repeat PWP2 family.
CC {ECO:0000256|ARBA:ARBA00010226}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAV91924.1}.
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DR EMBL; LIAE01006281; PAV91924.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A2M0A7; -.
DR STRING; 2018661.A0A2A2M0A7; -.
DR Proteomes; UP000218231; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0042254; P:ribosome biogenesis; IEA:UniProt.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 3.
DR InterPro; IPR024977; Apc4-like_WD40_dom.
DR InterPro; IPR027145; PWP2.
DR InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR InterPro; IPR007148; SSU_processome_Utp12.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR19858:SF0; PERIODIC TRYPTOPHAN PROTEIN 2 HOMOLOG-RELATED; 1.
DR PANTHER; PTHR19858; WD40 REPEAT PROTEIN; 1.
DR Pfam; PF12894; ANAPC4_WD40; 1.
DR Pfam; PF04003; Utp12; 1.
DR Pfam; PF00400; WD40; 3.
DR SMART; SM00320; WD40; 11.
DR SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 3.
DR PROSITE; PS50294; WD_REPEATS_REGION; 3.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000218231};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 343..405
FT /note="Anaphase-promoting complex subunit 4-like WD40"
FT /evidence="ECO:0000259|Pfam:PF12894"
FT REPEAT 349..390
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 391..432
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 477..516
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 749..854
FT /note="Small-subunit processome Utp12"
FT /evidence="ECO:0000259|Pfam:PF04003"
SQ SEQUENCE 872 AA; 98399 MW; 12411457515B9FF8 CRC64;
MDVKFNFSNL IGSVYRNGQI AFSPDGYSVY SPVGNKISIF DLKNNVSRTL SFESLFNIVT
ISVSSKGTHF VVANEAGDVL YVNLHSENLL HKFRANRTIR ALQFSPDDQM LAICRDFDLQ
IHKLNQMKCS VYRPLQLYMT YNLSTETLNC LDWSFDGCLI VAGGDDKVVR VVGSKRYRNV
HILQFGLHKG PIVNCQFFKE SYDLISVCRR GVAYVWKSSV LPGDLVEGHW TNQEQTATED
GEQITRLFYN KTKRFSLLES SGSGKQVDVT AAKFHSESNL LVTAFSNGSF VLHEIPTFAL
IHNLRVSDYA VSTVAINRTG DWLGIGCGQG SNAQLIVWEW QSETYALKQQ SHSQRISTIS
YSPDGSLLAT GAEDGKVKIW NNRTSFCIVT FDEHTSAVSC VKWTQSGKAI LSASLDGTVR
AHDMKRYRNF RTLVCPEPTQ LGSLVVDKSG DLVVAAGKEV YNIFVWSLEN GRLLDVLSGH
ELNISSIDLF GNTLVTASWD RTIRVWNVLD STSEITELHH EALFVRFSPS GDVVAVLTSD
SVITLYHTKE MALIGTIETA ADLDPSRSEN EQIKRDTSGK SKSFTSLDFS PNGHMLLVGG
ESNFFCLYSV SDRQIITKFK ITENRSLDGV VMDVNKRNFT EFGNMLLFDT SDEEYDGSNK
KAIKLPGSKH TDLGERRGKI AVEVQDVAFC PTGRRFAICS TEGVAVYSLD RISIFDPFQL
ETTTDPKFVK RSLMNREYSQ ALMGSLQLNN SDLIQSVIER TDAQEIILVV RSLPIQYAER
LLRWMANDRT MWNTQYPHLY MFWLKALLEE NGMRMKSHVD VATLTGLQQI VSYREQQINK
LADQNKFSLK YLLNSRRIRN EMKKEDDEPM EE
//
