ID A0A2A2RY52_9BACT Unreviewed; 392 AA.
AC A0A2A2RY52;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE RecName: Full=Nucleoside diphosphate kinase {ECO:0000256|RuleBase:RU004013};
DE EC=2.7.4.6 {ECO:0000256|RuleBase:RU004013};
GN ORFNames=B9S33_03285 {ECO:0000313|EMBL:PAW89328.1};
OS Pedosphaera sp. Tous-C6FEB.
OC Bacteria; Verrucomicrobiota; Verrucomicrobiae; Limisphaerales; Pedosphaera.
OX NCBI_TaxID=1982324 {ECO:0000313|EMBL:PAW89328.1, ECO:0000313|Proteomes:UP000218585};
RN [1] {ECO:0000313|EMBL:PAW89328.1, ECO:0000313|Proteomes:UP000218585}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tous-C6FEB {ECO:0000313|EMBL:PAW89328.1};
RA Cabello-Yeves P.J., Ghai R., Mehrshad M., Picazo A., Camacho A.,
RA Rodriguez-Valera F.;
RT "Genome diversity of Verrucomicrobia from freshwater lakes.";
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxyribonucleoside 5'-diphosphate + ATP = a 2'-
CC deoxyribonucleoside 5'-triphosphate + ADP; Xref=Rhea:RHEA:44640,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:61560, ChEBI:CHEBI:73316,
CC ChEBI:CHEBI:456216; EC=2.7.4.6;
CC Evidence={ECO:0000256|RuleBase:RU004013};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the NDK family. {ECO:0000256|ARBA:ARBA00008142}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAW89328.1}.
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DR EMBL; NEUT01000014; PAW89328.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A2RY52; -.
DR Proteomes; UP000218585; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004550; F:nucleoside diphosphate kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.30.70.141; Nucleoside diphosphate kinase-like domain; 2.
DR InterPro; IPR034907; NDK-like_dom.
DR InterPro; IPR036850; NDK-like_dom_sf.
DR InterPro; IPR023005; Nucleoside_diP_kinase_AS.
DR PANTHER; PTHR11349; NUCLEOSIDE DIPHOSPHATE KINASE; 1.
DR PANTHER; PTHR11349:SF91; NUCLEOSIDE DIPHOSPHATE KINASE; 1.
DR Pfam; PF00334; NDK; 2.
DR SMART; SM00562; NDK; 1.
DR SUPFAM; SSF54919; Nucleoside diphosphate kinase, NDK; 2.
DR PROSITE; PS00469; NDP_KINASES; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004013};
KW Kinase {ECO:0000256|RuleBase:RU004013, ECO:0000313|EMBL:PAW89328.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004013};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU004013}.
FT DOMAIN 182..380
FT /note="Nucleoside diphosphate kinase-like"
FT /evidence="ECO:0000259|SMART:SM00562"
SQ SEQUENCE 392 AA; 43144 MW; 8A96DF1C2E836069 CRC64;
MAQQLAYVIV TPYTLAKSRT GGILARLISR TGLELVAARL FGPRQELVEE YSKVIISAAD
PQDRGVQQLI HDYIVRELGP DPKSGRRRRC MMLLFKGDDA VRKIRAVVGN ISHTSRTGET
IRDTFGDYIL DERGQVRYFE PAVLAAPNAE EASQKLKLWA RYSDADGGIL DDCVEHPTDV
PVERTLVLIK PDNFRFATGR PGNVIDFFSR TGLYIVGIRV LHMSTAQAME FYGPVKDFLR
TKLKGVIAAK AKAVLEKDPS IGFTIPPEAE AKLADILGPV FGDNQFDNIV RFMCGRSESE
CPPDQLTEPG TEKCIALVYE GPNAVAKIRD VLGPTDPAKA PPGSIRREFG SNIMVNAAHA
SDAPESARRE LGIVKVEAND FKRVVEQFCG SL
//
