ID   A0A2A2S7Q8_9SPHI        Unreviewed;       447 AA.
AC   A0A2A2S7Q8;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=Proton-conducting membrane transporter {ECO:0008006|Google:ProtNLM};
GN   ORFNames=CKK33_14805 {ECO:0000313|EMBL:PAW94695.1};
OS   Mucilaginibacter sp. MD40.
OC   Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC   Sphingobacteriaceae; Mucilaginibacter.
OX   NCBI_TaxID=2029590 {ECO:0000313|EMBL:PAW94695.1, ECO:0000313|Proteomes:UP000242486};
RN   [1] {ECO:0000313|EMBL:PAW94695.1, ECO:0000313|Proteomes:UP000242486}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MD40 {ECO:0000313|EMBL:PAW94695.1,
RC   ECO:0000313|Proteomes:UP000242486};
RA   Wan X., Darris M., Hou S., Donachie S.P.;
RT   "Draft genome sequence of Mucilaginibacter sp. MD40, isolated from a
RT   biofilm in an air conditioner condensate pipe.";
RL   Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC       ECO:0000256|RuleBase:RU000320}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU000320}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PAW94695.1}.
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DR   EMBL; NRSW01000001; PAW94695.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2A2S7Q8; -.
DR   OrthoDB; 9807568at2; -.
DR   Proteomes; UP000242486; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR   GO; GO:0042773; P:ATP synthesis coupled electron transport; IEA:InterPro.
DR   InterPro; IPR001750; ND/Mrp_mem.
DR   InterPro; IPR003945; NU5C-like.
DR   InterPro; IPR001516; Proton_antipo_N.
DR   PANTHER; PTHR42829:SF1; INORGANIC CARBON TRANSPORTER SUBUNIT DABB-RELATED; 1.
DR   PANTHER; PTHR42829; NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 5; 1.
DR   Pfam; PF00361; Proton_antipo_M; 1.
DR   Pfam; PF00662; Proton_antipo_N; 1.
DR   PRINTS; PR01434; NADHDHGNASE5.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000242486};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU000320};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        17..37
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        49..78
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        107..124
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        144..163
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        175..194
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        206..226
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        246..274
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        295..313
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        325..343
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        355..377
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        389..407
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          12..50
FT                   /note="NADH-Ubiquinone oxidoreductase (complex I) chain 5
FT                   N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00662"
FT   DOMAIN          66..283
FT                   /note="NADH:quinone oxidoreductase/Mrp antiporter membrane
FT                   subunit"
FT                   /evidence="ECO:0000259|Pfam:PF00361"
SQ   SEQUENCE   447 AA;  49247 MW;  45322F87E104F80E CRC64;
     MIIALHFFIQ LFNLDRLSAI MISLVLFVAI CIGSFSLRYL RGDSNRKTFF VNLTIMVTTV
     IVMVSADNIF LLWSAWVISN VFLTRLMLHK AEWKAAKASA VLAQKNFALG ALFLGTALMI
     LYNLTGETSI QTILTKPLNS EWQAVVGLLL LMAAMSQSAL WPFHKWLTSS LNSPTPVSAI
     MHAGLVNGGG FLLARFAPML LGQPQILNLI FIMGIVTALL GTLWKLMQSD VKRMLACSTM
     GQMGFMIAQC GLGLFPAAVA HLCWHGLFKA YLFLSSGSAA KEKRLDLDYP PSFKDFAKAL
     FCGVLAAATF SITSEKHLLV ADTSLFLTFL SLIAGTQFAL PIVRGQSGIK FLAGAGAGIL
     MGAFYGLNVY IIEWVLAPLH LSIPQPLNFV HFTGGGLLFV SWLYMLFMPD PNKRALPEWL
     LKGYVKMLNA SQPHRKTITA NRNEYQF
//