ID   A0A2A2TKB8_9CYAN        Unreviewed;       360 AA.
AC   A0A2A2TKB8;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Secretion protein HlyD {ECO:0000313|EMBL:PAX56567.1};
GN   ORFNames=CK510_10000 {ECO:0000313|EMBL:PAX56567.1};
OS   Calothrix elsteri CCALA 953.
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Calotrichaceae;
OC   Calothrix.
OX   NCBI_TaxID=987040 {ECO:0000313|EMBL:PAX56567.1, ECO:0000313|Proteomes:UP000218238};
RN   [1] {ECO:0000313|EMBL:PAX56567.1, ECO:0000313|Proteomes:UP000218238}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CCALA 953 {ECO:0000313|EMBL:PAX56567.1,
RC   ECO:0000313|Proteomes:UP000218238};
RA   Gagunashvili A.N., Elster J., Andresson O.S.;
RT   "Draft genome sequence of filamentous cyanobacterium Calothrix elsteri
RT   CCALA 953.";
RL   Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PAX56567.1}.
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DR   EMBL; NTFS01000084; PAX56567.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2A2TKB8; -.
DR   OrthoDB; 9811754at2; -.
DR   Proteomes; UP000218238; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   Gene3D; 2.40.30.170; -; 1.
DR   Gene3D; 2.40.50.100; -; 1.
DR   InterPro; IPR043602; CusB_dom_1.
DR   InterPro; IPR032317; HlyD_D23.
DR   PANTHER; PTHR30386; MEMBRANE FUSION SUBUNIT OF EMRAB-TOLC MULTIDRUG EFFLUX PUMP; 1.
DR   PANTHER; PTHR30386:SF24; MULTIDRUG RESISTANCE EFFLUX PUMP; 1.
DR   Pfam; PF00529; CusB_dom_1; 1.
DR   Pfam; PF16576; HlyD_D23; 1.
DR   SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE   4: Predicted;
KW   Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022519};
KW   Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000218238};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        54..72
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          81..297
FT                   /note="RND efflux pump membrane fusion protein barrel-
FT                   sandwich"
FT                   /evidence="ECO:0000259|Pfam:PF16576"
FT   DOMAIN          298..355
FT                   /note="Cation efflux system protein CusB"
FT                   /evidence="ECO:0000259|Pfam:PF00529"
FT   REGION          1..25
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          296..324
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          186..213
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        1..17
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   360 AA;  39152 MW;  E7C709C4F941FB8D CRC64;
     MESIDSSSTQ QVIDTDEQPT PVDGRDVTAI TQVDVSENTD GGKKSGFRQM LPKIIIGVIL
     GAGAIASGIY HYRWSEYSKY HLTTDVAYTS ADSFPVTSRV AGIVTQITVK ENEAVNPGSV
     LIKLDPREIQ ASVVQAKAAL DVAKQQAEVT RENINNVPPT ILSEPLSPIT GNQPRLVLPK
     LPQSVNKQIE VNRQQYKAAL ATVTQRQAEL KQTELQLSYA NINAIAPGQI GNVNIRVGQQ
     VQPGQTLLEI VQPNPWIVAN FPENQLERIQ PGQKAQIKIA AFPSRKFVGK VESVSPTPVN
     SIAVPSPNST NPANNYSNNP NPSNNVRRIP VKIVFEPDSI KDFESRIAPG MSADVVIRTK
//