ID A0A2A3AHJ9_9MICC Unreviewed; 582 AA.
AC A0A2A3AHJ9;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=AMP-dependent synthetase {ECO:0000313|EMBL:PBB09266.1};
GN ORFNames=CKW39_03330 {ECO:0000313|EMBL:PBB09266.1};
OS Kocuria sp. WRN011.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC Kocuria.
OX NCBI_TaxID=2029858 {ECO:0000313|EMBL:PBB09266.1, ECO:0000313|Proteomes:UP000218573};
RN [1] {ECO:0000313|EMBL:PBB09266.1, ECO:0000313|Proteomes:UP000218573}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WRN011 {ECO:0000313|EMBL:PBB09266.1,
RC ECO:0000313|Proteomes:UP000218573};
RA Zhang G., Wu G.;
RT "Kocuria alkalisoli sp. nov., isolated from saline alkaline soil.";
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC {ECO:0000256|ARBA:ARBA00006432}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PBB09266.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; NSGI01000002; PBB09266.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A3AHJ9; -.
DR OrthoDB; 9803968at2; -.
DR Proteomes; UP000218573; Unassembled WGS sequence.
DR GO; GO:0016878; F:acid-thiol ligase activity; IEA:UniProt.
DR GO; GO:0016405; F:CoA-ligase activity; IEA:UniProt.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43605:SF10; ACYL-COA SYNTHETASE MEDIUM CHAIN FAMILY MEMBER 3; 1.
DR PANTHER; PTHR43605; ACYL-COENZYME A SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 3: Inferred from homology;
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Reference proteome {ECO:0000313|Proteomes:UP000218573}.
FT DOMAIN 53..419
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 469..546
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
FT REGION 553..582
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 582 AA; 65248 MW; 4D7B5964BC63204C CRC64;
MTVTNEFRTA RDHLVSLQQD WERAREEFVW PRFDHFNFGF DWFDQVAASP ERKDQDALII
LEEDGSELRR TFGELGRDSN KVANWLREQG VQRGDRVILM LNNQVELWES MLACIKLEAV
MVPTTTQMGP ADLEDRVTRA EAKWAIVGMQ DAPKFAPVDG DYTVIYVPGV YTPADQVKEP
QAGGRTVINY NEAYDASPEL SQDSPTGADE TLLLYFTSGT TSKPKLVEHT HTSYPVGHLS
TMYWIGLEPG DIHLNVASPG WAKHAWSNFF APWIAEATIF VYNFRKFDAA ALMSVMDKIG
VTSLCAPPTV WRMLIKADLS LLQTAPQKTV SAGEPLNAEV IEQVNRAWGC TIRDGFGQTE
SSLQVANTPG RRIVIGSMGV PLPGFDVVLI DPMTDEEADE GELCLRLDPR PVGLMRGYYG
DKAKTDDVFR NGLYHTGDVV SRDENGIFTY VGRADDVFKS SDYKVSPFEL ESVLVEHPAV
MEAAIVPTPD ELRLAIPKAF VTLSSGYEPT AETATEILQF CLSKLPPYKR IRRIEFLELP
KTISGKIRRV ELRKAEEQRS ESGEAPEGYG TEFREEDLTL KR
//
