ID   A0A2A3E568_APICC        Unreviewed;       193 AA.
AC   A0A2A3E568;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=SHSP domain-containing protein {ECO:0000259|PROSITE:PS01031};
GN   ORFNames=APICC_01375 {ECO:0000313|EMBL:PBC26319.1};
OS   Apis cerana cerana (Oriental honeybee).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Apoidea;
OC   Anthophila; Apidae; Apis.
OX   NCBI_TaxID=94128 {ECO:0000313|EMBL:PBC26319.1, ECO:0000313|Proteomes:UP000242457};
RN   [1] {ECO:0000313|EMBL:PBC26319.1, ECO:0000313|Proteomes:UP000242457}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   TISSUE=Pupae without intestine {ECO:0000313|EMBL:PBC26319.1};
RA   Diao Q., Sun L., Zheng H., Zheng H., Xu S., Wang S., Zeng Z., Hu F., Su S.,
RA   Wu J.;
RT   "Genomic and transcriptomic analysis on Apis cerana provide comprehensive
RT   insights into honey bee biology.";
RL   Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the small heat shock protein (HSP20) family.
CC       {ECO:0000256|PIRNR:PIRNR036514, ECO:0000256|PROSITE-ProRule:PRU00285,
CC       ECO:0000256|RuleBase:RU003616}.
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DR   EMBL; KZ288395; PBC26319.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2A3E568; -.
DR   SMR; A0A2A3E568; -.
DR   STRING; 94128.A0A2A3E568; -.
DR   Proteomes; UP000242457; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   CDD; cd06526; metazoan_ACD; 1.
DR   Gene3D; 2.60.40.790; -; 1.
DR   InterPro; IPR002068; A-crystallin/Hsp20_dom.
DR   InterPro; IPR001436; Alpha-crystallin/sHSP_animal.
DR   InterPro; IPR008978; HSP20-like_chaperone.
DR   PANTHER; PTHR45640:SF13; HEAT SHOCK PROTEIN 22-RELATED; 1.
DR   PANTHER; PTHR45640; HEAT SHOCK PROTEIN HSP-12.2-RELATED; 1.
DR   Pfam; PF00011; HSP20; 1.
DR   PIRSF; PIRSF036514; Sm_HSP_B1; 1.
DR   PRINTS; PR00299; ACRYSTALLIN.
DR   SUPFAM; SSF49764; HSP20-like chaperones; 1.
DR   PROSITE; PS01031; SHSP; 1.
PE   3: Inferred from homology;
KW   Metal-binding {ECO:0000256|PIRSR:PIRSR036514-1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000242457};
KW   Stress response {ECO:0000256|ARBA:ARBA00023016};
KW   Zinc {ECO:0000256|PIRSR:PIRSR036514-1}.
FT   DOMAIN          64..174
FT                   /note="SHSP"
FT                   /evidence="ECO:0000259|PROSITE:PS01031"
FT   REGION          173..193
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         112
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR036514-1"
FT   BINDING         114
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR036514-1"
FT   BINDING         119
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR036514-1"
SQ   SEQUENCE   193 AA;  22489 MW;  56081BD6E535B5A4 CRC64;
     MNLESLLLPY LWENMERAHS TINPNLRVRI NPENLGSKIM HVYDFLPQKT SPKLHMDYYR
     PWGELLRKSE GGASTVTADK NQFRVDLDVQ QFSPEEINVK VVDRFVIVEA KHEEKEDEHG
     WISRQFMRKY IIPEQCDIDQ ASSKLSSDGV LSIIVPRKQK VISEGERVIN IEHTGKPCDA
     QNEERKEKEE DVE
//