ID   A0A2A3E6V5_APICC        Unreviewed;       339 AA.
AC   A0A2A3E6V5;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Cysteine and histidine-rich protein {ECO:0000313|EMBL:PBC26771.1};
GN   ORFNames=APICC_01081 {ECO:0000313|EMBL:PBC26771.1};
OS   Apis cerana cerana (Oriental honeybee).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Apoidea;
OC   Anthophila; Apidae; Apis.
OX   NCBI_TaxID=94128 {ECO:0000313|EMBL:PBC26771.1, ECO:0000313|Proteomes:UP000242457};
RN   [1] {ECO:0000313|EMBL:PBC26771.1, ECO:0000313|Proteomes:UP000242457}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   TISSUE=Pupae without intestine {ECO:0000313|EMBL:PBC26771.1};
RA   Diao Q., Sun L., Zheng H., Zheng H., Xu S., Wang S., Zeng Z., Hu F., Su S.,
RA   Wu J.;
RT   "Genomic and transcriptomic analysis on Apis cerana provide comprehensive
RT   insights into honey bee biology.";
RL   Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the ZFTRAF1 family.
CC       {ECO:0000256|ARBA:ARBA00034319}.
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DR   EMBL; KZ288369; PBC26771.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2A3E6V5; -.
DR   STRING; 94128.A0A2A3E6V5; -.
DR   Proteomes; UP000242457; Unassembled WGS sequence.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd16505; RING-HC_CYHR1; 1.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR   InterPro; IPR039338; ZFTRAF1.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   InterPro; IPR001293; Znf_TRAF.
DR   PANTHER; PTHR23059; CYSTEINE AND HISTIDINE-RICH PROTEIN 1; 1.
DR   PANTHER; PTHR23059:SF4; CYSTEINE AND HISTIDINE-RICH PROTEIN 1; 1.
DR   SUPFAM; SSF57850; RING/U-box; 1.
DR   SUPFAM; SSF49599; TRAF domain-like; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
DR   PROSITE; PS50145; ZF_TRAF; 1.
PE   3: Inferred from homology;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW   ProRule:PRU00207}; Reference proteome {ECO:0000313|Proteomes:UP000242457};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00207};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00207}.
FT   DOMAIN          65..110
FT                   /note="RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50089"
FT   DOMAIN          131..169
FT                   /note="TRAF-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50145"
FT   ZN_FING         131..169
FT                   /note="TRAF-type"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00207"
FT   REGION          1..51
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..20
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        23..51
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   339 AA;  38895 MW;  82D4286D23E96E80 CRC64;
     MADPNNEAAS SSSVSEQAPT ATPIRDDLEK IEDFLEPDKK RRKVSRNDGK TEQKLEHRLG
     GILCCAVCLD LPKAAVYQCT NGHLMCAGCF THVLADARLR DEMATCPNCR IEISRTSPSR
     NLAVEKAVSE LPAECQYCAK EFPRNSLERH EETMCEERIS SCKYSRIGCP WRGPNHERPE
     HEAHCVHPHR SGLDVMEALR DIDARTLEEH LQMKPYRTDE FVHKLFYETS RFTAFNNQWV
     VKARINNSQR DPTQSSERDM TYQLILKTKT TYPLPLHYLI LKGPFGDMKV QPRIHKFEFT
     DQENESPYLP LPLPDTAECN RLLAARAISF RLIMFLASK
//