ID   A0A2A3EC53_APICC        Unreviewed;       843 AA.
AC   A0A2A3EC53;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=XK-related protein {ECO:0000256|RuleBase:RU910716};
GN   ORFNames=APICC_06014 {ECO:0000313|EMBL:PBC29317.1};
OS   Apis cerana cerana (Oriental honeybee).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Apoidea;
OC   Anthophila; Apidae; Apis.
OX   NCBI_TaxID=94128 {ECO:0000313|EMBL:PBC29317.1, ECO:0000313|Proteomes:UP000242457};
RN   [1] {ECO:0000313|EMBL:PBC29317.1, ECO:0000313|Proteomes:UP000242457}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   TISSUE=Pupae without intestine {ECO:0000313|EMBL:PBC29317.1};
RA   Diao Q., Sun L., Zheng H., Zheng H., Xu S., Wang S., Zeng Z., Hu F., Su S.,
RA   Wu J.;
RT   "Genomic and transcriptomic analysis on Apis cerana provide comprehensive
RT   insights into honey bee biology.";
RL   Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU910716}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141,
CC       ECO:0000256|RuleBase:RU910716}.
CC   -!- SIMILARITY: Belongs to the XK family. {ECO:0000256|ARBA:ARBA00008789,
CC       ECO:0000256|RuleBase:RU910716}.
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DR   EMBL; KZ288288; PBC29317.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2A3EC53; -.
DR   STRING; 94128.A0A2A3EC53; -.
DR   Proteomes; UP000242457; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR018629; XK-rel.
DR   PANTHER; PTHR16024; XK-RELATED PROTEIN; 1.
DR   PANTHER; PTHR16024:SF4; XK-RELATED PROTEIN; 1.
DR   Pfam; PF09815; XK-related; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU910716};
KW   Reference proteome {ECO:0000313|Proteomes:UP000242457};
KW   Transmembrane {ECO:0000256|RuleBase:RU910716};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU910716}.
FT   TRANSMEM        20..44
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU910716"
FT   TRANSMEM        56..77
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU910716"
FT   TRANSMEM        101..121
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU910716"
FT   TRANSMEM        188..208
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU910716"
FT   TRANSMEM        228..252
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU910716"
FT   TRANSMEM        259..279
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU910716"
FT   TRANSMEM        291..310
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU910716"
FT   TRANSMEM        322..340
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU910716"
FT   TRANSMEM        360..379
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU910716"
FT   REGION          453..477
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          562..621
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          672..768
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        570..617
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        673..687
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        717..739
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        743..757
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   843 AA;  95153 MW;  0F155AB1F84F3264 CRC64;
     MAQHLQTQHQ HEFLPLCDVL FNIISLASYF CDVVFDFAMI YALAQHSIAP PILFPLSVML
     IATSLIISQI ISVRWYLWGA RGKLTDNTIT DCNGKKENGN WTIWCVLLLH STQVGVLWRY
     FKLFIPVNLT YVKHEVRELC VLRLIHAFCE AAPMLLLQLY LLSIGINNDS NNEVEKTKEN
     ESRDNDKLAK LTAVSAGLSL WSVCWAVASF SKGAARLRNL ERLVLTWLGV LAQLAWRLGT
     VSARVGVLVA YASLYGGQWL LIVMALHWLS MLMWLLLTPD GLFHGGEHLP ILRKTSLASL
     LAFVYIFAYV NLHETNHRQK MIIFYTVMFL ENSLLIGVWI VGVNRTDFLP HQHHPNPVTL
     VLTLLALFFG GMFFMGLYYR FFHVRRLRYE AGGRMTASNL TALSNQDNLE EKQIEYTENK
     KLNMNVGVRR VKLSNGGIPG VFNCRFANPT VVNPNRKKKK PTTFVPLPPP QSQSGTVTAP
     INTLDESKQW HGINSNSRQL IPFWKKSVNS NAIQNGHMNE QKIGTDSGTA GSLNVNLIRE
     KLQEKKQQQL RELRAIQEEI KEGKLFPPPS ASASSFSSSP ASTQQPPPNT KLHTSPSSPL
     FTSEPSVGDQ NGGVTLSSWP PVKMHCLLPP PPSSSYYPNI HPSNSWRTTQ RERADTPEIL
     LAPRCLPHHY SHWTPSSHVN PRQNGGEESS KGEGEIEGEL SDMEGSQISL PRSYTLPREF
     KYHHPNNTAR ERERRVGNNK ISASRFYLPS TNSSDGDVDS ADNEEETDSE IHYRIKNNHG
     SNNHSETQQQ QQRFTFEDNK NEFLNSGSTA AVIVSGNSYL NNSQDLLRPS QLFRNRVKHE
     TKL
//