ID A0A2A3EDJ5_APICC Unreviewed; 1442 AA.
AC A0A2A3EDJ5;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Intron-binding protein aquarius {ECO:0000313|EMBL:PBC29091.1};
GN ORFNames=APICC_04443 {ECO:0000313|EMBL:PBC29091.1};
OS Apis cerana cerana (Oriental honeybee).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Apoidea;
OC Anthophila; Apidae; Apis.
OX NCBI_TaxID=94128 {ECO:0000313|EMBL:PBC29091.1, ECO:0000313|Proteomes:UP000242457};
RN [1] {ECO:0000313|EMBL:PBC29091.1, ECO:0000313|Proteomes:UP000242457}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Pupae without intestine {ECO:0000313|EMBL:PBC29091.1};
RA Diao Q., Sun L., Zheng H., Zheng H., Xu S., Wang S., Zeng Z., Hu F., Su S.,
RA Wu J.;
RT "Genomic and transcriptomic analysis on Apis cerana provide comprehensive
RT insights into honey bee biology.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PIRNR:PIRNR038901}.
CC -!- SIMILARITY: Belongs to the CWF11 family.
CC {ECO:0000256|PIRNR:PIRNR038901}.
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DR EMBL; KZ288292; PBC29091.1; -; Genomic_DNA.
DR STRING; 94128.A0A2A3EDJ5; -.
DR Proteomes; UP000242457; Unassembled WGS sequence.
DR GO; GO:0005681; C:spliceosomal complex; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:InterPro.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:InterPro.
DR CDD; cd17935; EEXXQc_AQR; 1.
DR CDD; cd18808; SF1_C_Upf1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR048966; Aquarius_b-barrel.
DR InterPro; IPR048967; Aquarius_insert.
DR InterPro; IPR032174; Aquarius_N.
DR InterPro; IPR026300; CWF11_fam.
DR InterPro; IPR045055; DNA2/NAM7-like.
DR InterPro; IPR041679; DNA2/NAM7-like_C.
DR InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR047187; SF1_C_Upf1.
DR PANTHER; PTHR10887; DNA2/NAM7 HELICASE FAMILY; 1.
DR PANTHER; PTHR10887:SF5; RNA HELICASE AQUARIUS; 1.
DR Pfam; PF13086; AAA_11; 1.
DR Pfam; PF13087; AAA_12; 1.
DR Pfam; PF16399; Aquarius_N_1st; 1.
DR Pfam; PF21143; Aquarius_N_2nd; 1.
DR Pfam; PF21144; Aquarius_N_3rd; 1.
DR PIRSF; PIRSF038901; AQR_cwf11; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW mRNA processing {ECO:0000256|PIRNR:PIRNR038901};
KW mRNA splicing {ECO:0000256|PIRNR:PIRNR038901};
KW Nucleus {ECO:0000256|PIRNR:PIRNR038901};
KW Reference proteome {ECO:0000313|Proteomes:UP000242457}.
FT DOMAIN 23..415
FT /note="RNA helicase aquarius N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16399"
FT DOMAIN 495..659
FT /note="RNA helicase aquarius beta-barrel"
FT /evidence="ECO:0000259|Pfam:PF21143"
FT DOMAIN 707..783
FT /note="RNA helicase aquarius insertion"
FT /evidence="ECO:0000259|Pfam:PF21144"
FT DOMAIN 795..1097
FT /note="DNA2/NAM7 helicase helicase"
FT /evidence="ECO:0000259|Pfam:PF13086"
FT DOMAIN 1106..1296
FT /note="DNA2/NAM7 helicase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13087"
FT REGION 1374..1423
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1375..1391
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1397..1411
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1442 AA; 168460 MW; A8EC7506D364F753 CRC64;
MENQVTVKSN NPAPTVEQIN ADRITQLANK YWAPHTMDSH LPFNSQIVED IYIQEICASK
FSIRRIMMLE FSQYLENFLW PNYNAKIATR AHTMSIVVMV NEKFRERVQV WEAFEKNSEY
FSDFFQKVLE ACLEESIMDF DLKEQTALIV FLNHCFNSME VSLVREEVKR LVSLAMWISL
QQGRRELEFR KYPKWRKYWK VIRKKDNPEY KEKLEWERKF LHKLMIKFMT ILETIPEEGL
LLPDKVRYCE RFLELVIDLE ALLPTRRFFN TVMDDCHLVV RCQLSNLLHR LEGELFGQLL
EMLKFYARFE INEESGDPLT DHDMTQLHYT KITSLQKAVF AKFPDLRSFA LANVASVDTR
EALYKHFGLL SQEKLRSIAS YLSLVPSKER EKEENWFRYD IDFLRELLIS RHERRASQLE
ELNEMPLYPT EEIIWNESIV PTEYFSGEGC LALPKLNLQF LTLHDYLLRN FNLFRLESTY
EIRQDIEDAV SRLSPWRAED GGVYFGGWAR MAQPITQFAV VEVAKPNIGE KRPSRVRADV
TINLSVRKEI KSEWENLRKH DVCFLITVKP QNLIGTKYSH KLPFVPQVGL TTVRGCEVEG
MLDSNGRVIE DGPEPRPILP GDTRTYRVWL DCNQYRIDMD NASHGSEDVY ESFNVIMRRK
PKENNFKAVL ETIRELMNTE CVVPDWLHDI ILGYGDPGAA RYSRMPNEIA TMDFNDTFLD
INHLKNSFPQ YEIKISTDEE SKLVRPFRLT FEDVLAKHNN ESIKKVIKVE PHVPPSRGPY
KANEPKKNQI PFTPTQIEAI RAGMQPGLTL VVGPPGTGKT DVAVQIISNL YHNFPNQRTL
IVTHSNQALN QLFEKIMALD IDERHLLRLG HGEEALETEK DFSRYGRVNY VLAKRLDLLM
EVQRLQESLN VKGDVAYTCE TAGHFFMYQI LTRWERFETR SKQRQKTEND SAFIIDEEFS
FHKFFDNAPK PLFKRNTFEE DFEIARSCFR YIERIFAQLE EFRAFELLRS GLDRSKYLLV
KEAKVIAMTC THAALKRREL VDMGFKYDNI LMEESAQILE IETFIPLLLQ NPQDGYNRLK
RWIMIGDHHQ LPPVIKNMAF QKYSNMEQSL FARFVRLGVP TVDLDGQGRA RPSICNLYNW
RYKKLGNLAH VENSPEYLVA NAGFLYDFQL INVEDFNGVG ESEPSAYFYQ NLAEAEYCVA
VFMYMRLLGY PADKISILTT YNGQKHLIRD VINIRCASNP LIGRPNKVTT VDKYQGQQND
YILLSLVKTR AVGHLRDARR LVVAMSRARL GLYVFARVSL FKNCFELTPA FAQLMQRPLK
LQLLPQEHYP TERLNNTIPS TSSMEIEDMP HMAKFVYDYY IEKVSGIKES QKVWQKPGMV
QTPNNPSYKI STHPGADDDT DDEELNQMDD EQENTKEENG ELKFEIIKNL VEDLTSENED
ND
//
