ID A0A2A3EDT8_APICC Unreviewed; 1105 AA.
AC A0A2A3EDT8;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Embryonic polarity protein dorsal {ECO:0000313|EMBL:PBC29878.1};
GN ORFNames=APICC_05149 {ECO:0000313|EMBL:PBC29878.1};
OS Apis cerana cerana (Oriental honeybee).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Apoidea;
OC Anthophila; Apidae; Apis.
OX NCBI_TaxID=94128 {ECO:0000313|EMBL:PBC29878.1, ECO:0000313|Proteomes:UP000242457};
RN [1] {ECO:0000313|EMBL:PBC29878.1, ECO:0000313|Proteomes:UP000242457}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Pupae without intestine {ECO:0000313|EMBL:PBC29878.1};
RA Diao Q., Sun L., Zheng H., Zheng H., Xu S., Wang S., Zeng Z., Hu F., Su S.,
RA Wu J.;
RT "Genomic and transcriptomic analysis on Apis cerana provide comprehensive
RT insights into honey bee biology.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KZ288269; PBC29878.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A3EDT8; -.
DR STRING; 94128.A0A2A3EDT8; -.
DR Proteomes; UP000242457; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000977; F:RNA polymerase II transcription regulatory region sequence-specific DNA binding; IEA:UniProt.
DR GO; GO:0048468; P:cell development; IEA:UniProt.
DR GO; GO:0010604; P:positive regulation of macromolecule metabolic process; IEA:UniProt.
DR GO; GO:0051173; P:positive regulation of nitrogen compound metabolic process; IEA:UniProt.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:UniProt.
DR GO; GO:0048731; P:system development; IEA:UniProt.
DR CDD; cd01177; IPT_NFkappaB; 1.
DR CDD; cd07887; RHD-n_Dorsal_Dif; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.60.40.340; Rel homology domain (RHD), DNA-binding domain; 1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR002909; IPT_dom.
DR InterPro; IPR033926; IPT_NFkappaB.
DR InterPro; IPR000451; NFkB/Dor.
DR InterPro; IPR008967; p53-like_TF_DNA-bd_sf.
DR InterPro; IPR030492; RHD_CS.
DR InterPro; IPR032397; RHD_dimer.
DR InterPro; IPR011539; RHD_DNA_bind_dom.
DR InterPro; IPR037059; RHD_DNA_bind_dom_sf.
DR PANTHER; PTHR24169:SF20; DORSAL-RELATED IMMUNITY FACTOR DIF-RELATED; 1.
DR PANTHER; PTHR24169; NUCLEAR FACTOR NF-KAPPA-B PROTEIN; 1.
DR Pfam; PF16179; RHD_dimer; 1.
DR Pfam; PF00554; RHD_DNA_bind; 1.
DR PRINTS; PR00057; NFKBTNSCPFCT.
DR SMART; SM00429; IPT; 1.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF49417; p53-like transcription factors; 1.
DR PROSITE; PS01204; REL_1; 1.
DR PROSITE; PS50254; REL_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000242457}.
FT DOMAIN 42..221
FT /note="RHD"
FT /evidence="ECO:0000259|PROSITE:PS50254"
FT REGION 615..650
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1047..1073
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 628..642
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1105 AA; 125518 MW; 7CCD75897423AC44 CRC64;
MEQFHDMSDG NIHMSDVIEV IETDTKYNGR EDQIPREMNT ERLLPYVEII EQPASKALRF
RYECEGRSAG SIPGVNSTSE NKTFPTIKIV GYKGRALVVV SCVTKDQPYR PHPHNLVGKE
ACKQGVCTVE VSSENMTVTF ANLGIQCVKK KDIEEALKIR EEIRVDPFRT GFEHKRQPTS
IDLNAVRLCF QVFLEGSQKR KFNVPLQPVV SDPIFDKKAM SDLVICKLSH SNASVAGGME
MILLCEKVAK EDIQVRFFEE KDGQVLWEGF GDFQPVHVHK QTAIAFRTPT YRMQQVEQPV
QVYIQLKRPS DGATSEPFPF LMLPLGAGRP AFWSLRKAFA RKKTDYTSFG KILASEPTLF
SNVTPKFPRN IDEYNNNDFD TKKWNNKISA LRALNDLYNV KNTLDSYNGS MEINQNIAQN
IDHAKNTIID YRNNDLSINE EKRTIENEQL NRMYKSYPNY IDKETKDMNL EILTRPKSNT
VENACVLKNT EIFKDKSDWF DYSEVSKWVQ KGQICLKEKE NEIDFKIEVT EDCNKSFNDL
LTQVAELDQI YADTHAKLVQ AAFEQNTTDQ SMDIDVCDNQ TYTSLQMAMK NPIEFTDLSN
ERKYEDVCVL KTDTNQSCPS PPVTTKRDGT QETEERLPPL PPKRIRKMPS MPLLPRPISC
HTTPDSFIEA PNKTLPSLPS TLTKNSKQGL FSKLFAKKVK KDKDTILNVS KETTQSLTTT
GNISYLTTNN TSNNSQLQIP RASVVSTTSV KSLRLEGDET PPYGMELTEA EHYALYTAMA
PHATASEFDE MSFYYSPVKK LRSKFIGLLS SEKIDILIFK SHVVNIQSFI DDPDSLRRKR
QKINNSQNAL VLRHVQAEAE MHAAMLNQYN FNIIKSEPTE RISPYEYPIG SGGSFPSLYP
MATTSPQSQS TIQTLRPQVS PDRTSPMDYR LYNPALIQSQ PSPQYPSTSS HILQQPSIRT
YTQQQFPYVH DTLQIQPQEQ LTLSKVTSNY HEEFQSLNNA VGEMEATNVT NILSMDNTQY
NLDLSLPQLD STELADLDIS LSENLSSGLS ISDSTKPETS KGINAEPSNI EESNNMTDSF
TRIANNTIQE LYTLNNIYKP TREVD
//
