ID   A0A2A3EFA7_APICC        Unreviewed;       782 AA.
AC   A0A2A3EFA7;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   SubName: Full=Phospholipase A-2-activating protein {ECO:0000313|EMBL:PBC30164.1};
GN   ORFNames=APICC_02873 {ECO:0000313|EMBL:PBC30164.1};
OS   Apis cerana cerana (Oriental honeybee).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Apoidea;
OC   Anthophila; Apidae; Apis.
OX   NCBI_TaxID=94128 {ECO:0000313|EMBL:PBC30164.1, ECO:0000313|Proteomes:UP000242457};
RN   [1] {ECO:0000313|EMBL:PBC30164.1, ECO:0000313|Proteomes:UP000242457}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   TISSUE=Pupae without intestine {ECO:0000313|EMBL:PBC30164.1};
RA   Diao Q., Sun L., Zheng H., Zheng H., Xu S., Wang S., Zeng Z., Hu F., Su S.,
RA   Wu J.;
RT   "Genomic and transcriptomic analysis on Apis cerana provide comprehensive
RT   insights into honey bee biology.";
RL   Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC   -!- SIMILARITY: Belongs to the WD repeat PLAP family.
CC       {ECO:0000256|ARBA:ARBA00008495}.
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DR   EMBL; KZ288266; PBC30164.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2A3EFA7; -.
DR   STRING; 94128.A0A2A3EFA7; -.
DR   Proteomes; UP000242457; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   CDD; cd00200; WD40; 1.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   Gene3D; 3.10.20.870; PFU (PLAA family ubiquitin binding), C-terminal domain; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR015155; PFU.
DR   InterPro; IPR038122; PFU_sf.
DR   InterPro; IPR013535; PUL_dom.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR001680; WD40_rpt.
DR   PANTHER; PTHR19849; PHOSPHOLIPASE A-2-ACTIVATING PROTEIN; 1.
DR   PANTHER; PTHR19849:SF0; PHOSPHOLIPASE A-2-ACTIVATING PROTEIN; 1.
DR   Pfam; PF09070; PFU; 1.
DR   Pfam; PF08324; PUL; 1.
DR   Pfam; PF00400; WD40; 7.
DR   SMART; SM00320; WD40; 7.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
DR   PROSITE; PS51394; PFU; 1.
DR   PROSITE; PS51396; PUL; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 3.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Reference proteome {ECO:0000313|Proteomes:UP000242457};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW   ProRule:PRU00221}.
FT   REPEAT          25..56
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          117..158
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          241..282
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   DOMAIN          379..478
FT                   /note="PFU"
FT                   /evidence="ECO:0000259|PROSITE:PS51394"
FT   DOMAIN          518..780
FT                   /note="PUL"
FT                   /evidence="ECO:0000259|PROSITE:PS51396"
SQ   SEQUENCE   782 AA;  86576 MW;  CB1CC2A7718DF2AB CRC64;
     MSLLRASHDY QSGMAKPYYK LRTSLFGHTS DVRAVATFAD GTIVSTSRDE TARIWKSCGN
     DKDYEHTATL KGHSNFVTSV CVINPSEQNP TGFIITGSHD KTIRIYISDQ AEPINIIKSH
     QDTVCKLTTG TKEGTFLSSS WDMSAKLWNL SDLSKPQLNL LGHTAAVWCV ADLLSGYIIT
     GSADKLVIIW TSDGSIHHKL IGHTDCVRDI SAINSNEFLT CANDATVRHW NVSLGTCLGT
     YCGHENYIYS ILALENGTSI FTCSEDRTLR IWHNSELSQT ITLPTQSVWC LALLPNGDVV
     TGSSDGVVRI FSCNPERYAD SETLQEFEQQ VASVKLNAQQ ELGGIKVKDL PDAKALLQPG
     QRDGQTKIIN DGDAIRAYSW SQNEQRWIKI GNVMGASGGS VATSGKQLYN GIEYDYVFSV
     DIQDGIPPLK LPYNNDQDPW HVAQKFLHDN GLSQLFLDQV ANFIIKNSES APVLKTDAQY
     ADPFTGGSRY IPQSTTNTAS HEFTRSTASN SSDASVPSYI PHTKYLKLEQ ANLSQILEKI
     KELNTKQNDP FKVPNDKLES LVKLAGDQAS EQLKTDALST LKILLNWSDD ILFPVLDITR
     LAVLCREVND VLCTEELLQI VKKHIKPDAL PSNQMLTFRL LANMFSHEKG EKLCLNCKDE
     ILKLLSELES LTNKNNQVAI STYILNLTVA LNKYNDTLGK IECLNAMFSL LPRLNESEAV
     FRTLVALGTL LSTTSNSEDR NNLIKAVRQS EVALNILYTI SETTIPTDKL ANCSKQIISL
     II
//