ID A0A2A3EHP6_APICC Unreviewed; 656 AA.
AC A0A2A3EHP6;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Protein phosphatase {ECO:0000313|EMBL:PBC30719.1};
GN ORFNames=APICC_09759 {ECO:0000313|EMBL:PBC30719.1};
OS Apis cerana cerana (Oriental honeybee).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Apoidea;
OC Anthophila; Apidae; Apis.
OX NCBI_TaxID=94128 {ECO:0000313|EMBL:PBC30719.1, ECO:0000313|Proteomes:UP000242457};
RN [1] {ECO:0000313|EMBL:PBC30719.1, ECO:0000313|Proteomes:UP000242457}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Pupae without intestine {ECO:0000313|EMBL:PBC30719.1};
RA Diao Q., Sun L., Zheng H., Zheng H., Xu S., Wang S., Zeng Z., Hu F., Su S.,
RA Wu J.;
RT "Genomic and transcriptomic analysis on Apis cerana provide comprehensive
RT insights into honey bee biology.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the PP2C family.
CC {ECO:0000256|RuleBase:RU003465}.
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DR EMBL; KZ288254; PBC30719.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A3EHP6; -.
DR STRING; 94128.A0A2A3EHP6; -.
DR Proteomes; UP000242457; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
DR CDD; cd00143; PP2Cc; 1.
DR Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR InterPro; IPR015655; PP2C.
DR InterPro; IPR000222; PP2C_BS.
DR InterPro; IPR036457; PPM-type-like_dom_sf.
DR InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR PANTHER; PTHR13832; PROTEIN PHOSPHATASE 2C; 1.
DR PANTHER; PTHR13832:SF818; SD03870P; 1.
DR Pfam; PF00481; PP2C; 1.
DR SMART; SM00332; PP2Cc; 1.
DR SUPFAM; SSF81606; PP2C-like; 1.
DR PROSITE; PS01032; PPM_1; 1.
DR PROSITE; PS51746; PPM_2; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU003465};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Protein phosphatase {ECO:0000256|ARBA:ARBA00022912,
KW ECO:0000256|RuleBase:RU003465};
KW Reference proteome {ECO:0000313|Proteomes:UP000242457}.
FT DOMAIN 81..344
FT /note="PPM-type phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS51746"
FT REGION 402..427
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 498..543
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 596..620
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 506..538
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 656 AA; 73975 MW; A9B8C8A0FF3B0A40 CRC64;
MVSIFRVILQ CPASLQAYLV HQVIQEIKSM CKKQPEDCGF KSQEKTYTSL KLMQAIINKV
NEICTRYLDN SRLALLPPPP STPLPQITAG GSKNCRRKME DRYVILHDLH TTFGIEDDSI
ANYYAVFDGH AGQDAAVYCA AHLHQYLTES IYYPTDPERA LRDAFLTTDR QFIEKSKTQK
LCGGTTAVCT LILNKRLYVA WVGDSTAMLI KRDSVVQLVN PHRLHREDEV QRIRKAGGVV
MPSMGTMRVN GVLGVSRAIG DVRYKPFVTG EPEVKSVPLD GTEDFLVLAT DGLTDYLNPK
EILTILYHEI QRNPNGFKRA YQILLHWAKQ GGSEDNITVV VVLLTPANAI AARPLNAHPY
FRLQVNDILE KMNSKDKPLF MDIDDAHNAI NSNILKQSMI SQEPRDDDGG ILAASNGKHE
NGDADYDYSD LGPETNVDAI DDVTMPVKNL SYEFYKDDDI CHEDGQTDND SNILDNRDMD
ESINANLNAN TNIITHEQIT DNNLHENNDD DDDDDDDEVD ENDDDDNNDD ELHQDNDDVP
DDEVMVSKTI EDDIPENEIN NCEKINNEIC EPLMENIVDE KKTRMEDQAD MPQDVVDEAG
PVDYDESPPS PQANSKCELQ SKPRFYERPI SSWIARLVTN VLKIQFQCKS KIDSSV
//
