ID A0A2A3EKI6_APICC Unreviewed; 1084 AA.
AC A0A2A3EKI6;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 13-SEP-2023, entry version 15.
DE SubName: Full=Dyslexia-associated protein {ECO:0000313|EMBL:PBC31541.1};
GN ORFNames=APICC_09549 {ECO:0000313|EMBL:PBC31541.1};
OS Apis cerana cerana (Oriental honeybee).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Apoidea;
OC Anthophila; Apidae; Apis.
OX NCBI_TaxID=94128 {ECO:0000313|EMBL:PBC31541.1, ECO:0000313|Proteomes:UP000242457};
RN [1] {ECO:0000313|EMBL:PBC31541.1, ECO:0000313|Proteomes:UP000242457}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Pupae without intestine {ECO:0000313|EMBL:PBC31541.1};
RA Diao Q., Sun L., Zheng H., Zheng H., Xu S., Wang S., Zeng Z., Hu F., Su S.,
RA Wu J.;
RT "Genomic and transcriptomic analysis on Apis cerana provide comprehensive
RT insights into honey bee biology.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KZ288232; PBC31541.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A3EKI6; -.
DR STRING; 94128.A0A2A3EKI6; -.
DR Proteomes; UP000242457; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd19756; Bbox2; 1.
DR CDD; cd00146; PKD; 2.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 5.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR029865; KIAA0319-like.
DR InterPro; IPR011106; MANSC_N.
DR InterPro; IPR022409; PKD/Chitinase_dom.
DR InterPro; IPR035986; PKD_dom_sf.
DR InterPro; IPR000315; Znf_B-box.
DR PANTHER; PTHR46182; FI19480P1; 1.
DR PANTHER; PTHR46182:SF2; FI19480P1; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR SMART; SM00765; MANEC; 1.
DR SMART; SM00089; PKD; 5.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF49299; PKD domain; 4.
DR PROSITE; PS50119; ZF_BBOX; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00024};
KW Reference proteome {ECO:0000313|Proteomes:UP000242457};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00024};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00024}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..1084
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012042420"
FT TRANSMEM 845..870
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 978..1023
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT REGION 886..905
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1084 AA; 121697 MW; 37AE4BA658213647 CRC64;
MFKILYLELY LLLFGNCIGD YSDWDTKWQI LCPGLYPRAF TSYTPHGNLS SGIYTMQPHL
SSMKHCVATC CTKTTCNVAL MHNGTCYHVQ CESSKICMPL YRKDLANENP PSMILVKPVE
EDEMWSDLLD QMNDDTGGFL MDGTEGDHIL FGGSSCITQT NCLEHEICVK SEDKSDIGIC
QCSTGFKRNM AGICTLMEDI ELGVTPQMKT QSIKDSNTSV KPPIKRLLVS VVSKEVRLPE
NEVTLSAYTV PAEQKNEHYN YAWSLLSQPD GHTGIMTNQN RMTVKLSNLS EGLYTFKVTV
NGPNAYGEAY ANVSVLPPKR INQPPIAIIS PASQVVKLPN TGAVLDGSSS KDDDRIISYR
WELQQGPIGY HPNLVDTPTL QLDNLIPGNY TFKLTVEDSN HITNSTSANI TVLKVTDYPP
SANAGQDIII YLPQNTLTLN GNLSTDDHGI ANWEWTKSPS DQNKAVDMQN TRTPYLQLSN
LEEGMYTFVL KVTDDSEQSS IAEIHVFVKP PTNKPPKADA GEDITIALPE TKTVLDGRKS
KDDIKIVSYH WEQMSGPNKA EFSAMNESVT NITKLTKGDY EFKLTVIDDN GNKDSDAVKV
KVTQNKNAPP KANAGGDQVV VAPISALIIN GSRSIDDLRI SEWMWTRDPS SLAIGTIVQN
TDKSPILMLT DIVPGRYVFR LKVMDDQGLN SEDTVSVIVK PDPQLLHLVE LTLNIGANML
TVSQKNSLVL KLQMLLRDEA SIIVRNLRAE PHTGRAVLIF YVEKKGKVTM HGPEVVKRLK
EKLRQDSGLL QLSVANIDTA ICQNNCSGHG VCDQETRLCM CEAFWMQNLI QKYFGNGDSN
CDWSILYVII ALLSLVVCWV GLIWGLVCLC QRICIGKRRS LRTKKKPPRY SLLQPEPEDE
SNTFSTHKMV LSESDTDSDD ILFEHRKAKN SSQAMVQCST CLHNFCLDCG IEHQQQITME
LKPLKHSLRP LWEATKIRRT VLCQEHPTHA LHFYCIACQQ VSCKECIWSN QHRGHASENA
IEAAKQVIWY LRKMLQKAKI LLNMLLTQYD RDAFLNTSEE IKNIFISMNY RKILHVYTLK
HVYR
//
