ID   A0A2A3ES82_APICC        Unreviewed;       867 AA.
AC   A0A2A3ES82;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   13-SEP-2023, entry version 22.
DE   SubName: Full=Heat shock {ECO:0000313|EMBL:PBC34653.1};
GN   ORFNames=APICC_05859 {ECO:0000313|EMBL:PBC34653.1};
OS   Apis cerana cerana (Oriental honeybee).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Apoidea;
OC   Anthophila; Apidae; Apis.
OX   NCBI_TaxID=94128 {ECO:0000313|EMBL:PBC34653.1, ECO:0000313|Proteomes:UP000242457};
RN   [1] {ECO:0000313|EMBL:PBC34653.1, ECO:0000313|Proteomes:UP000242457}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   TISSUE=Pupae without intestine {ECO:0000313|EMBL:PBC34653.1};
RA   Diao Q., Sun L., Zheng H., Zheng H., Xu S., Wang S., Zeng Z., Hu F., Su S.,
RA   Wu J.;
RT   "Genomic and transcriptomic analysis on Apis cerana provide comprehensive
RT   insights into honey bee biology.";
RL   Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family.
CC       {ECO:0000256|ARBA:ARBA00007381}.
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DR   EMBL; KZ288189; PBC34653.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2A3ES82; -.
DR   SMR; A0A2A3ES82; -.
DR   STRING; 94128.A0A2A3ES82; -.
DR   Proteomes; UP000242457; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   CDD; cd10228; HSPA4_like_NDB; 1.
DR   Gene3D; 1.20.1270.10; -; 1.
DR   Gene3D; 3.30.30.30; -; 1.
DR   Gene3D; 3.30.420.40; -; 2.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR029048; HSP70_C_sf.
DR   InterPro; IPR029047; HSP70_peptide-bd_sf.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR45639:SF4; HSC70CB, ISOFORM G; 1.
DR   PANTHER; PTHR45639; HSC70CB, ISOFORM G-RELATED; 1.
DR   Pfam; PF00012; HSP70; 2.
DR   PRINTS; PR00301; HEATSHOCK70.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR   SUPFAM; SSF100934; Heat shock protein 70kD (HSP70), C-terminal subdomain; 2.
DR   SUPFAM; SSF100920; Heat shock protein 70kD (HSP70), peptide-binding domain; 1.
DR   PROSITE; PS01036; HSP70_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000242457};
KW   Stress response {ECO:0000313|EMBL:PBC34653.1}.
FT   REGION          505..577
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          815..867
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        552..566
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        821..844
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        845..861
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   867 AA;  97741 MW;  5CC4B293326D53EF CRC64;
     MAAMSVIGID FGNESCYVAV ARAGGIETIA NDYSLRSTPS CVAFSGKNRI LGVAAKNQMV
     TNMKNTIHGF KRLLGRKYND PQVQRELQML PFKVTHQSDG SIGIHVQYLG EEHIFSPEQI
     TAMLFTKLKD ISETALQTIV NDCVISVPSY FTQAERQALL DAARIAGLNV LRLFNETTAT
     ALCYGIYKQD LPAPETSPRN VVFVDCGYAS LQVSICAFHK GKLKMIASAA DSQLGGRNID
     SILAEHFCKE FQSRYNIDPH TNPRAYIRLL GEVEKLKKQM SANSTTLPLN IECFMDEKDV
     HGEMKRADME AMCAHLFKRV ESTLRQCLED SKLKLEDIHS VELAGGFSRV PAIKRLVEEV
     FGRTVSTTLN QDEAVARGCA LQCAMLSPAV RVRDFSVTDI QPYPLKLTWD PTQGEEGEME
     IFGHNHPVPF SKTLTFYRSN PFTLTASYSV PPSSYPQTHI GTYTIKNVKP TPEGELSKVK
     VKVRVNLNGI LTIVSASLIE KRELTQQEKE EEEKQQQQHQ QQQNNMDVDQ QQDKKDKPDQ
     EAQANEPPAP EVSMDKTRRN SDADDGGRGA RGSAPSYSSR ILSWLSSSDD KNDENKGKKK
     VPIRTIDLPV EMREYGLSQR DFDAAVEKEA KMIAEDKQEK ERVDARNALE EYVYDLRAKL
     SEEDQLSTFV TEIDKEALCR TLDETENWLY EEGEDCQRQI YSERLTRLKS QGEPIKERRV
     EYEGRGHALD DLSAALQLAK KGVDLIRASS GKDDKYSHLT EEEVKKVEKA VHEKWTWLEE
     KRILLASTPR TQQPPVTVAQ IRGEKLTLDS IVLPILNKPK PKIEPPKEEK PKDKTGEDHQ
     KNQNSQGDGH IQTNQQQQSQ EEKMDVE
//