ID   A0A2A3EUJ7_APICC        Unreviewed;      1012 AA.
AC   A0A2A3EUJ7;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=DNA damage-regulated autophagy modulator protein {ECO:0000313|EMBL:PBC34952.1};
GN   ORFNames=APICC_08490 {ECO:0000313|EMBL:PBC34952.1};
OS   Apis cerana cerana (Oriental honeybee).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Apoidea;
OC   Anthophila; Apidae; Apis.
OX   NCBI_TaxID=94128 {ECO:0000313|EMBL:PBC34952.1, ECO:0000313|Proteomes:UP000242457};
RN   [1] {ECO:0000313|EMBL:PBC34952.1, ECO:0000313|Proteomes:UP000242457}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   TISSUE=Pupae without intestine {ECO:0000313|EMBL:PBC34952.1};
RA   Diao Q., Sun L., Zheng H., Zheng H., Xu S., Wang S., Zeng Z., Hu F., Su S.,
RA   Wu J.;
RT   "Genomic and transcriptomic analysis on Apis cerana provide comprehensive
RT   insights into honey bee biology.";
RL   Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the DRAM/TMEM150 family.
CC       {ECO:0000256|ARBA:ARBA00006565}.
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DR   EMBL; KZ288185; PBC34952.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2A3EUJ7; -.
DR   Proteomes; UP000242457; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR019402; Frag1/DRAM/Sfk1.
DR   PANTHER; PTHR21324:SF2; EG:22E5.9 PROTEIN; 1.
DR   PANTHER; PTHR21324; FASTING-INDUCIBLE INTEGRAL MEMBRANE PROTEIN TM6P1-RELATED; 1.
DR   Pfam; PF10277; Frag1; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000242457};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        24..44
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        65..84
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        90..118
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        130..155
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        175..193
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          298..317
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          353..383
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          449..482
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          537..569
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          638..720
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          847..964
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        460..479
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        537..566
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        642..671
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        672..687
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        695..720
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        867..890
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        922..951
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1012 AA;  114508 MW;  F0D48284D4BC2595 CRC64;
     MLGHVEAGFP YISDTATYAP ESCIFSQFIN MFAMLMSFVV YIRYSQVKEC SSTFRLQTSL
     PKWNHWALIF GLLSTFGLSV VANFQETSVL VVHFIGALLC FGGGTAYFWT QAVCTFYLHP
     LGCSLRLAHI RTALSTFCTV CFVVTLITGV LARLAYKGTN PRKWYREDGG WELHVASTIT
     EWLCAGAFAV YILTFSEEFR DVKVIHPKIV CTLSRTRLSN ETLNESQDSM GRGAGGYVNL
     LSHSPVNTPC PGYRYRESRE PLLDEAAPLI ATTPPAACDV EGRTDVLCPV QIHVHDPSAR
     ERRRQMDEED ETERVQKWGG NHRSRNWIDL DENVLDGYIL IDDSCLESGV IPDETKELPY
     PEGGVEVDEE NEDADSHGKD DGSIYSIAKR GISRRGPRGE EFDLSSTYPL ANSHGNAYKE
     SSSHTRYTEL YSELAVKNYL EGNREEMGNY SVANSHGDHS VSSENRERSL RENAETDQSV
     WDTRQHTNYE VANSHSNYRV FYDSQTQQRE LLRTSGWSIE SWREHLMANN YVVEERKQKS
     ENAGQLVRDD ESTKTSRSEA KSDPGSEPAC DIEQCLVQIE ESLLNIEQNL LHVQDLDIPE
     LRNLLYKSPS IEKSLYEVQD LLYADGIVPV INKRKSSTLI SEDEEEDEEE EEEEEEEEEE
     EEEEEEEEEE VWVGRNITVK DNDNEDDDAA IGTFDASNEE SSDTANIDEN NRSGSVDNCS
     TTDCTNGSTI FHEDVPVDPN CNEKTMNFIP NSLNKTLPRR IILDGAKENI RLCSSEPEES
     TTVDYNLNTT CAEKKLFCRD KCHSRTNSLD ENSTFSNFDS FDKRETGKSS LQNLLFESAN
     GNLFDRSGKA RSEEMLPRTP RNRCFNASRK KSKEKQAKTE DFRRKLEPVS SSRRFANASN
     EQKRAKISKE SVNANAPRPI REKSPNRTRR GTISADKVQE KDKEKCTDNK RKRKKISSRS
     QSSSENALVP SKLISLSLSL LLAALLQAVR CLTDLVEDAF RSVNCDRSGL LQ
//