ID   A0A2A3EUW5_APICC        Unreviewed;       401 AA.
AC   A0A2A3EUW5;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 13.
DE   SubName: Full=Zinc-type alcohol dehydrogenase protein {ECO:0000313|EMBL:PBC34939.1};
GN   ORFNames=APICC_04208 {ECO:0000313|EMBL:PBC34939.1};
OS   Apis cerana cerana (Oriental honeybee).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Apoidea;
OC   Anthophila; Apidae; Apis.
OX   NCBI_TaxID=94128 {ECO:0000313|EMBL:PBC34939.1, ECO:0000313|Proteomes:UP000242457};
RN   [1] {ECO:0000313|EMBL:PBC34939.1, ECO:0000313|Proteomes:UP000242457}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   TISSUE=Pupae without intestine {ECO:0000313|EMBL:PBC34939.1};
RA   Diao Q., Sun L., Zheng H., Zheng H., Xu S., Wang S., Zeng Z., Hu F., Su S.,
RA   Wu J.;
RT   "Genomic and transcriptomic analysis on Apis cerana provide comprehensive
RT   insights into honey bee biology.";
RL   Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KZ288185; PBC34939.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2A3EUW5; -.
DR   STRING; 94128.A0A2A3EUW5; -.
DR   Proteomes; UP000242457; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0044238; P:primary metabolic process; IEA:UniProt.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 2.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   PANTHER; PTHR43401; L-THREONINE 3-DEHYDROGENASE; 1.
DR   PANTHER; PTHR43401:SF2; L-THREONINE 3-DEHYDROGENASE; 1.
DR   Pfam; PF13602; ADH_zinc_N_2; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000242457};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        175..195
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        216..236
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          41..395
FT                   /note="Enoyl reductase (ER)"
FT                   /evidence="ECO:0000259|SMART:SM00829"
SQ   SEQUENCE   401 AA;  44287 MW;  9653C23B290840EB CRC64;
     MPIELESVTP ITHKPCSPCN GEKKMNKLCK QVSIDSPNVT GREWVFSFDV PVPDVPAHGA
     RIRVMCAGAC YHPRRSPSLS SLTSVSSASS LATDVSMEGD FPVSMPHHGV RDAALFPGYE
     VAGVIESLGA NVPEDCEYTV GDRVILYPYE GIPNGYVEYL VVYDLKYLIK IPDNVSLSVA
     AMLPAGALLA MNTVFATHEH IQALLKQRGV NSVCKILIVG TGGLALWALR IAAYHFSNMK
     DRVTITIASL KDDGLTMAQE FQRVNVVQWS EDLYEKQLIE RTMDACQGHV DVVIDFGTTS
     RSLHRSMQCL SKGGVVFVIK EVADRLLPKF SRRAEEWQQN IRPVEPGTLE QLRQLVELVA
     SGEIEPPPHT VYPAEEVLDV VRKLCHSEIQ GRAILRFYPA D
//