ID   A0A2A3GX67_9ACTN        Unreviewed;       297 AA.
AC   A0A2A3GX67;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=RNA polymerase subunit sigma-24 {ECO:0000313|EMBL:PBC60261.1};
DE   Flags: Fragment;
GN   ORFNames=BKI49_30030 {ECO:0000313|EMBL:PBC60261.1};
OS   Streptomyces sp. Tue6028.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=2036037 {ECO:0000313|EMBL:PBC60261.1, ECO:0000313|Proteomes:UP000217789};
RN   [1] {ECO:0000313|EMBL:PBC60261.1, ECO:0000313|Proteomes:UP000217789}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tue6028 {ECO:0000313|EMBL:PBC60261.1,
RC   ECO:0000313|Proteomes:UP000217789};
RA   Greule A., Flemming S., Bechthold A.;
RT   "The Draft Genome Sequence of Streptomyces sp. Tue6028 - Producer of
RT   Polyketomycin and Foxicin.";
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBUNIT: Interacts transiently with the RNA polymerase catalytic core
CC       formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1
CC       omega subunit) to form the RNA polymerase holoenzyme that can initiate
CC       transcription. {ECO:0000256|ARBA:ARBA00011344}.
CC   -!- SIMILARITY: Belongs to the sigma-70 factor family. ECF subfamily.
CC       {ECO:0000256|ARBA:ARBA00010641}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PBC60261.1}.
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DR   EMBL; MLCE01000032; PBC60261.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2A3GX67; -.
DR   Proteomes; UP000217789; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0016987; F:sigma factor activity; IEA:InterPro.
DR   GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProt.
DR   Gene3D; 1.10.1740.10; -; 1.
DR   Gene3D; 3.10.450.50; -; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR032710; NTF2-like_dom_sf.
DR   InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR   InterPro; IPR007627; RNA_pol_sigma70_r2.
DR   InterPro; IPR013249; RNA_pol_sigma70_r4_t2.
DR   InterPro; IPR013325; RNA_pol_sigma_r2.
DR   InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR   InterPro; IPR037401; SnoaL-like.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   NCBIfam; TIGR02937; sigma70-ECF; 1.
DR   PANTHER; PTHR30173:SF43; ECF RNA POLYMERASE SIGMA FACTOR SIGI-RELATED; 1.
DR   PANTHER; PTHR30173; SIGMA 19 FACTOR; 1.
DR   Pfam; PF04542; Sigma70_r2; 1.
DR   Pfam; PF08281; Sigma70_r4_2; 1.
DR   Pfam; PF12680; SnoaL_2; 1.
DR   SUPFAM; SSF54427; NTF2-like; 1.
DR   SUPFAM; SSF88946; Sigma2 domain of RNA polymerase sigma factors; 1.
DR   SUPFAM; SSF88659; Sigma3 and sigma4 domains of RNA polymerase sigma factors; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000217789};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          19..80
FT                   /note="RNA polymerase sigma-70 region 2"
FT                   /evidence="ECO:0000259|Pfam:PF04542"
FT   DOMAIN          121..172
FT                   /note="RNA polymerase sigma factor 70 region 4 type 2"
FT                   /evidence="ECO:0000259|Pfam:PF08281"
FT   DOMAIN          187..288
FT                   /note="SnoaL-like"
FT                   /evidence="ECO:0000259|Pfam:PF12680"
FT   NON_TER         297
FT                   /evidence="ECO:0000313|EMBL:PBC60261.1"
SQ   SEQUENCE   297 AA;  32109 MW;  13B00F85554EC90D CRC64;
     MSGGTVFVTT ELSAVLGERR HLTNIAYRLL GSLAEAEDAV QETYARWYAL SSRQQEAIAS
     PGAWLTTVAT RVCLDLLGSA RVRRERYVGA WVPEPLPDRT EWTNRAVDPA DQVTLDESVH
     MAFLVVLESM TPAERVAFVL HDVFRYPFAE VAEILDRSPG ACRELASSAR RRVRAAHTPV
     SGQAGLVRDF KQAWEARDIE ALVGLLAPDA TMTVDGGGVV GAALRPVEGG ERIAQYLAHF
     AEKAPGLTLL ERTVNGQSGL VAQHAGITVT VAAFSGSGGR VTHIWAVRNP EKLGAWT
//