ID A0A2A3GZ37_9ACTN Unreviewed; 295 AA.
AC A0A2A3GZ37;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=Dehydrogenase {ECO:0000313|EMBL:PBC61384.1};
GN ORFNames=BKI49_25720 {ECO:0000313|EMBL:PBC61384.1};
OS Streptomyces sp. Tue6028.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=2036037 {ECO:0000313|EMBL:PBC61384.1, ECO:0000313|Proteomes:UP000217789};
RN [1] {ECO:0000313|EMBL:PBC61384.1, ECO:0000313|Proteomes:UP000217789}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tue6028 {ECO:0000313|EMBL:PBC61384.1,
RC ECO:0000313|Proteomes:UP000217789};
RA Greule A., Flemming S., Bechthold A.;
RT "The Draft Genome Sequence of Streptomyces sp. Tue6028 - Producer of
RT Polyketomycin and Foxicin.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the HIBADH-related family.
CC {ECO:0000256|ARBA:ARBA00009080}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PBC61384.1}.
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DR EMBL; MLCE01000026; PBC61384.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A3GZ37; -.
DR Proteomes; UP000217789; Unassembled WGS sequence.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006115; 6PGDH_NADP-bd.
DR InterPro; IPR015815; HIBADH-related.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR048666; RedAm-like_C.
DR PANTHER; PTHR43580; OXIDOREDUCTASE GLYR1-RELATED; 1.
DR PANTHER; PTHR43580:SF2; OXIDOREDUCTASE GLYR1-RELATED; 1.
DR Pfam; PF03446; NAD_binding_2; 1.
DR Pfam; PF21761; RedAm-like_C; 1.
DR PIRSF; PIRSF000103; HIBADH; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000217789}.
FT DOMAIN 13..163
FT /note="6-phosphogluconate dehydrogenase NADP-binding"
FT /evidence="ECO:0000259|Pfam:PF03446"
FT DOMAIN 169..294
FT /note="NADPH-dependent reductive aminase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21761"
SQ SEQUENCE 295 AA; 30261 MW; A379997B63BBE900 CRC64;
MAGMTNDLEN TSVAVLGLGA MGQALAAAFL RAGHRTTVWN RSPGKGDDLV ARGARRADSA
AEAVRAAELV VVCVVDHGAV RAVLDATADE LPGRVLVNLT SDTPERARAT AAWADERGID
HLDGSIMVPV PAIGGPDALV FYSGPRAAYD KHERALRALG GRPAYLGEEP GLAAVYDLAL
LDFFYSSMAG LVHAFALAGA DGVPAASLAP YLDTIAAILP PIAAGTAEDI DAGRYPGAAA
NLAMMAAGAG HVLEAAEHRG LDVSTLRSVK EIADRAVARG HAADSWASTV EVVRG
//
