ID A0A2A3H1P1_9ACTN Unreviewed; 738 AA.
AC A0A2A3H1P1;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=HTH luxR-type domain-containing protein {ECO:0000259|PROSITE:PS50043};
GN ORFNames=BKI49_19275 {ECO:0000313|EMBL:PBC62388.1};
OS Streptomyces sp. Tue6028.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=2036037 {ECO:0000313|EMBL:PBC62388.1, ECO:0000313|Proteomes:UP000217789};
RN [1] {ECO:0000313|EMBL:PBC62388.1, ECO:0000313|Proteomes:UP000217789}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tue6028 {ECO:0000313|EMBL:PBC62388.1,
RC ECO:0000313|Proteomes:UP000217789};
RA Greule A., Flemming S., Bechthold A.;
RT "The Draft Genome Sequence of Streptomyces sp. Tue6028 - Producer of
RT Polyketomycin and Foxicin.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PBC62388.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; MLCE01000021; PBC62388.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A3H1P1; -.
DR Proteomes; UP000217789; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd06170; LuxR_C_like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR InterPro; IPR039420; WalR-like.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR43214; TWO-COMPONENT RESPONSE REGULATOR; 1.
DR Pfam; PF00196; GerE; 1.
DR Pfam; PF17874; TPR_MalT; 1.
DR SMART; SM00421; HTH_LUXR; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50043; HTH_LUXR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000217789}.
FT DOMAIN 671..736
FT /note="HTH luxR-type"
FT /evidence="ECO:0000259|PROSITE:PS50043"
SQ SEQUENCE 738 AA; 78387 MW; 9E38562BA3EC4259 CRC64;
MTSSVAAFKL HPATQPPHLL SRPRLLRRLD AATEPVVVLS ASAGAGKTVL LTEWSRRLVA
RGECAWLSLD AYDNAPGRLW SCILRALHQV LPDLPARLDD DGWTVDAWLE EILPSLVSGL
GAQRPLTLIL DGLESITDVD AVRSLGDFLA RLPHGFRIIV STRHLLGSPL PALRARGLVA
ELDQHDLAFT PEEAQAVLTG LLGSAPSAET SSALYEATEG WAAGLCIMGR ALARSVNESD
MDRELALGRQ AVSEYLAGEV LYRLTTEQRE FLLRTSVLDE LSAGPCQALA GEQAGVVLRE
LARTVQLLVP AADPSAYRHH RALSSLLSDV LMSQGPDTVV SLHRSAAQWY ARRRETTAAV
RHWVRGGDEP AAVASVLDGW EEAVSAGRGA EVSHWLDLLP PRMVAADGRL CVVAAMAALS
GGAPETARRW LDVAQLRHTG PETVGEGSTV SDAAAVAQAV ACCLKGEVLT ADRLGESAVA
GTMPLTSWRA LACTARGTAL LWTRRYGEAE ALLGEATRDA HAAGHGLVLV RALGLRAVCA
LLAGRHEQAR VLSDEALQAA ATAGLGGHFV AMSAYIGRAG VLLEEGDIDG AERVLADAEA
VLAGSPRAGS EPQVRALCHV MRARLEKARH NTDAAREARE AAERAAARCE SPGALTDLLG
RVGEDTVVTP AAPGPQDLSL GERRVLRALC GPLTLREIAS ELYVSHNTVK TQVRAIFRKL
DAHDRGAAVA RARERGVL
//
